A mini review on green nanotechnology and its development in biological effects

Archives of Microbiology, Journal Year: 2023, Volume and Issue: 205(4)

Published: March 22, 2023

The utilization of living organisms for the creation inorganic nanoscale particles is a potential new development in realm biotechnology. An essential milestone nanotechnology process creating dependable and environmentally acceptable metallic nanoparticles. Due to its increasing popularity ease, use ambient biological resources quickly becoming more significant this field study. phrase "green nanotechnology" has gained lot attention refers variety procedures that eliminate or do away with hazardous compounds repair environment. Green nanomaterials can be used biotechnological sectors such as medicine biology, well food textile industries, wastewater treatment agriculture field. construction an updated level knowledge study systems might support revolutionize nanoparticles (NPs) are presented article.

Language: Английский

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Potential Antimicrobial and Antibiofilm Properties of Copper Oxide Nanoparticles: Time-Kill Kinetic Essay and Ultrastructure of Pathogenic Bacterial Cells

Applied Biochemistry and Biotechnology, Journal Year: 2022, Volume and Issue: 195(1), P. 467 - 485

Published: Sept. 10, 2022

Abstract Mycosynthesis of nanoparticle (NP) production is a potential ecofriendly technology for large scale production. In the present study, copper oxide nanoparticles (CuONPs) have been synthesized from live cell filtrate fungus Penicillium chrysogenum . The created CuONPs were characterized via several techniques, namely Fourier transform infrared (FTIR) spectroscopy, X-ray diffraction (XRD), transmission electron microscope (TEM), scanning (SEM), and energy-dispersive spectroscopy (EDX). Furthermore, biosynthesized performed against biofilm forming Klebsiella oxytoca ATCC 51,983, Escherichia coli 35,218, Staphylococcus aureus 25,923, Bacillus cereus 11,778. anti-bacterial activity result was shown with zone inhibition determined to be 14 ± 0.31 mm, 16 0.53 11 0.57 10 mm respectively. more susceptible minimal inhibitory concentration (MIC) values 6.25 3.12 µg/mL, respectively, while , MIC value 12.5 25 μg/mL, minimum (MBIC) evident, that excellent anti-biofilm at sub-MIC levels reducing formation by 49% 59% results indicated MBIC on higher than 200 μg/mL 256 suggesting these could not inhibit mature formatted in vitro. Overall, all clearly confirmed ability prepared offer smart approach biomedical therapy resistant microorganisms because its promoted antimicrobial action, but only specified purposes.

Language: Английский

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Biosynthesis of Silver and Gold Nanoparticles and Their Efficacy Towards Antibacterial, Antibiofilm, Cytotoxicity, and Antioxidant Activities

Applied Biochemistry and Biotechnology, Journal Year: 2022, Volume and Issue: 195(2), P. 1158 - 1183

Published: Nov. 7, 2022

The World Health Organization (WHO) reports that the emergence of multidrug-resistant and slow advent novel more potent antitumor antimicrobial chemotherapeutics continue to be highest concern for human health. Additionally, stability, low solubility, negative effects existing drugs make them ineffective. Studies into alternative tactics tackle such tenacious diseases was sparked by anticancer antibacterial. Silver (Ag) gold (Au) nanoparticles (NPs) were created from Trichoderma saturnisporum, much productive fungal strain. Functional extracellular enzymes proteins carried out activities synthesis capping generated nano-metals. Characterization done on obtained Ag-NPs Au-NPs through UV-vis, FTIR, XRD, TEM, SEM. versus methicillin-sensitive Staphylococcus aureus (MSSA) methicillin-resistant (MRSA), Pseudomonas aeruginosa, Klebsiella pneumoniae, antibacterial assessed. In particular, effective against pathogenic bacteria than Au-NPs. Furthermore, antibiofilm study shown had activity Ag-NPs. Interestingly, applying DPPH procedure, these noble metallic NPs antioxidant activity, in which IC50 73.5 μg/mL 190.0 μg/mL, respectively. According cytotoxicity evaluation results, alteration cells as loss their typical shape, partial or complete monolayer, granulation, shrinking, cell rounding with normal Vero 693.68 661.24 Au-NPs, While cancer (Mcf7) 370.56 394.79 produced via green have potential employed medical industry beneficial nanocompounds.

Language: Английский

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Nanocomposite based on gold nanoparticles and carboxymethyl cellulose: Synthesis, characterization, antimicrobial, and anticancer activities

Journal of Drug Delivery Science and Technology, Journal Year: 2022, Volume and Issue: 77, P. 103874 - 103874

Published: Oct. 7, 2022

Language: Английский

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Antibacterial Activity of Green Synthesized Silver Nanoparticles Using Lawsonia inermis Against Common Pathogens from Urinary Tract Infection

Applied Biochemistry and Biotechnology, Journal Year: 2023, Volume and Issue: 196(1), P. 85 - 98

Published: April 26, 2023

Abstract New and creative methodologies for the fabrication of silver nanoparticles (Ag-NPs), which are exploited in a wide range consumer items, significant interest. Hence, this research emphasizes biological approach Ag-NPs through Egyptian henna leaves ( Lawsonia inermis Linn.) extracts analysis prepared Ag-NPs. Plant extract components were identified by gas chromatography mass spectrometry (GC-mass). The analyses carried out UV–visible (UV–Vis), X-ray diffraction (XRD), transmission electron microscope (TEM), scanning (SEM), Fourier transform infrared (FTIR) analysis. UV–Vis reveals that have maximum peak at 460 nm visible light. Structural characterization recorded peaks corresponded to Bragg’s diffractions nano-crystal, with average crystallite sizes varying from 28 60 nm. Antibacterial activities examined, it is observed all microorganisms very sensitive biologically synthesized

Language: Английский

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Green synthesized ZnO nanoparticles by Saccharomyces cerevisiae and their antibacterial activity and photocatalytic degradation

Biomass Conversion and Biorefinery, Journal Year: 2023, Volume and Issue: unknown

Published: Sept. 15, 2023

Abstract Many research papers are currently being written about various methodologies for the green synthesis of ZnO nanoparticles. In this study, nanoparticles were prepared by method using baker’s yeast ( Saccharomyces cerevisiae ). The characterization produced involved utilization XRD, FTIR, SEM, and TEM. investigation assessment antimicrobial potential photocatalytic degradation efficacy synthesized materials through Eriochrome Black T (EBT). results indicate that exhibit a spherical morphology, exhibiting diameters ranging from 13.0 to 20.0nm, with an average particle size 15.0nm. against S. aureus ) gram-positive E. coli gram-negative bacteria was tested conduction zone inhibition (ZOI) minimum inhibitory concentration (MIC) tests. This focused on study photocatalytic-degradation EBT in presence ultraviolet light. experiments impact factors, such as pH levels, initial concentration, nanocatalyst dosage, observed efficiency. vitro ZOI MIC assay, it (NPs) exhibited greater , measuring 23.1 mm 0.625 μg/ml. contrast, effectiveness ZnO-NPs comparatively lower, indicated 17.0 1.250μg/ml. greatest elimination, which achieved 83.0% equilibrium, found employing 20.0mg NPs at 3.0, according activity results. synthetic powerful antibacterial agents effective may be used treatment wastewater.

Language: Английский

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Biogenic metallic nanoparticles: biomedical, analytical, food preservation, and applications in other consumable products

Frontiers in Nanotechnology, Journal Year: 2023, Volume and Issue: 5

Published: May 2, 2023

Biogenic metallic nanoparticles (BMNPs) are nanostructure materials synthesized through biological processes that have gained significant attention due to their small size and high surface area-to-volume ratio. BMNPs several advantages over chemically ones eco-friendly synthesis regimen, sustainability, biocompatibility, diverse multifarious biomedical applications. Moreover, the superior cytocompatibility stability capping layer (MNPs), reduces like hood of toxicity side effects, making them a safer alternative traditional drug delivery methods. Among promising applications BMNPs, antibacterial activity, analytical sensing heavy metals, roles in food preservations been widely explored. In addition, imaging, also investigated for therapeutic activity such as antimicrobial efficacy against skin soft tissue nosocomial pathogens targeting cancer cells therapy. The present review bestows characterization techniques involved with MNPs compressive aspects biogenic using agricultural materials, which cost minimizes use hazardous chemicals. focuses on multifold including biomedical, analytical, preservation food, other consumable goods toxicological aspects.

Language: Английский

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Process optimization for green synthesis of silver nanoparticles using Rubus discolor leaves extract and its biological activities against multi-drug resistant bacteria and cancer cells

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: Feb. 19, 2024

Abstract Multi-drug resistant (MDR) bacteria are considered a serious public health threat. Also, increasing rate of resistance to anticancer drugs, as well their toxicity, is another point concern. Therefore, the new antibacterial and agents always needed. The synthesizing silver nanoparticles (AgNPs) using medicinal plants, an effective approach for developing novel agents. Rubus discolor , native species Caucasus region, produces leaves that typically discarded by-product raspberry production. present study has focused on optimizing green synthesis AgNPs R. extract through response surface methodology. optimal values were AgNO 3 concentration 7.11 mM, time 17.83 h, temperature 56.51 °C, percentage 29.22. production was confirmed UV–visible spectroscopy (λ max at 456.01 nm). TEM analysis revealed well-dispersed (an average size 37 XRD crystalline structure. EDX detected strong peak keV corresponded Ag. zeta potential value (− 44.2 mV) indicated stability nanoparticles. FT-IR spectra showed presence various functional groups from plant compounds, which play important role in capping bio-reduction processes. impressive activities against MDR Escherichia coli Pseudomonas aeruginosa (MIC ranging 0.93 3.75 mg ml −1 ). phytochemical phenolics, tannins, flavonoids AgNPs. They also significant cytotoxic effects A431, MCF-7, HepG2 cells (IC 50 11 49.1 µg −l

Language: Английский

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Green Synthesis of Silver Nanoparticles: A Comprehensive Review of Methods, Influencing Factors, and Applications

JCIS Open, Journal Year: 2024, Volume and Issue: 16, P. 100125 - 100125

Published: Oct. 11, 2024

Language: Английский

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Unveiling biological activities of biosynthesized starch/silver-selenium nanocomposite using Cladosporium cladosporioides CBS 174.62

BMC Microbiology, Journal Year: 2024, Volume and Issue: 24(1)

Published: March 8, 2024

Abstract Background and objectives Microbial cells capability to tolerate the effect of various antimicrobial classes represent a major worldwide health concern. The flexible multi-components nanocomposites have enhanced physicochemical characters with several improved properties. Thus, different biological activities biosynthesized starch/silver-selenium nanocomposite (St/Ag-Se NC) were assessed. Methodology St/Ag-Se NC was using Cladosporium cladosporioides CBS 174.62 ( C. ) strain. shape average particle size investigated scanning electron microscope (SEM) high-resolution transmission (HR-TEM), respectively. On other hand, on two cancer cell lines red blood (RBCs) evaluated its hydrogen peroxide (H 2 O scavenging Moreover, effects microbial species in both planktonic biofilm growth forms examined. Results successfully oval spherical mean diameter 67.87 nm as confirmed by HR-TEM analysis. showed promising anticancer activity toward human colorectal carcinoma (HCT-116) breast (MCF-7) where IC 50 21.37 19.98 µg/ml, Similarly, little RBCs observed low concentration. As well, highest H (42.84%) recorded at concentration mg/ml. Additionally, Staphylococcus epidermidis S. ATCC 12,228 Candida albicans 10,231 highly affected bacterial fungal strains minimum inhibitory concentrations (MICs) 18.75 noticeable dependent. A high suppression percentage, 87.5% 68.05%, aureus when exposed 1 mg/ml 0.5 mg/ml, Conclusion excellent antioxidant activity, haemocompatibility, anti-proliferative concentrations. Also, it exhibited antibiofilm activities.

Language: Английский

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