Mitochondrion, Journal Year: 2024, Volume and Issue: 78, P. 101942 - 101942
Published: Aug. 6, 2024
Language: Английский
Citations
11Cell fusion as a driver of metastasis: re-evaluating an old hypothesis in the age of cancer heterogeneity
Frontiers in Immunology, Journal Year: 2025, Volume and Issue: 16
Published: Feb. 4, 2025
Numerous studies have investigated the molecular mechanisms and signalling pathways underlying cancer metastasis, as there is still no effective treatment for this terminal stage of disease. However, exact processes that enable primary cells to acquire a metastatic phenotype remain unclear. Increasing attention has been focused on fusion with myeloid cells, phenomenon may result in hybrid so-called Tumour Hybrid Cells (THCs), enhanced migratory, angiogenic, immune evasion, colonisation, properties. This process shown potentially drive tumour progression, drug resistance, recurrence. In review, we explore potential govern cell fusion, mediators involved, characteristics acquired by fusion-derived hybrids, their clinical significance human cancer. Additionally, discuss emerging pharmacological strategies aimed at targeting fusogenic molecules means prevent dissemination.
Language: Английский
Citations
2The potential role of targeting the leptin receptor as a treatment for breast cancer in the context of hyperleptinemia: a literature review
Naunyn-Schmiedeberg s Archives of Pharmacology, Journal Year: 2024, Volume and Issue: unknown
Published: Nov. 20, 2024
Language: Английский
Citations
8CTCs Detection Methods In Vivo and In Vitro and Their Application in Tumor Immunotherapy
Journal of Surgical Oncology, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 29, 2025
ABSTRACT Circulating tumor cells (CTCs) are that detach from the primary site and enter bloodstream. They hold significant value for early detection, diagnosis, treatment of tumors. CTC detection methods can be classified into in vivo vitro techniques. Compared to traditional methods, causes less harm body allows earlier identification malignant tumors, thereby enabling timely improving patient survival rates. In recent years, has been widely used assess effectiveness immunotherapy. Dynamic monitoring CTCs help optimize clinical strategies. This review summarizes latest discusses their applications immunotherapy various common aiming provide better guidance support practice.
Language: Английский
Citations
0Mapping brain neural networks in stress brain connectivity
Progress in brain research, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 1, 2025
Language: Английский
Citations
0Inherently imperfect, inherently evolving – the pursuit of precision through biomarkers
Biomedical Journal, Journal Year: 2025, Volume and Issue: unknown, P. 100839 - 100839
Published: Feb. 1, 2025
Language: Английский
Citations
0Impact of positive feelings and negative feelings on brain cell regeneration and degeneration
Progress in brain research, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 1, 2025
Language: Английский
Citations
0Mitochondrial Dynamics Regulators in Cancer Metabolism and Progression
Mitochondrial Communications, Journal Year: 2025, Volume and Issue: unknown
Published: April 1, 2025
Language: Английский
Citations
0Emotional stress and cardiovascular health: Impacts on neurodegenerative disease progression
Progress in brain research, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 1, 2025
Language: Английский
Citations
0Mitochondrial dysfunction as a key player in aggravating periodontitis among diabetic patients: review of the current scope of knowledge
Naunyn-Schmiedeberg s Archives of Pharmacology, Journal Year: 2025, Volume and Issue: unknown
Published: April 24, 2025
Language: Английский
Citations
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