Chitosan–fucoidan encapsulating cinnamaldehyde composite coating films: Preparation, pH-responsive release, antibacterial activity and preservation for litchi

Carbohydrate Polymers, Journal Year: 2024, Volume and Issue: 333, P. 121968 - 121968

Published: Feb. 20, 2024

Language: Английский

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Marine algal polysaccharides for drug delivery applications: A review

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: 295, P. 139551 - 139551

Published: Jan. 7, 2025

Language: Английский

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Fucoidan/chitosan layered PLGA nanoparticles with melatonin loading for inducing intestinal absorption and addressing triple-negative breast cancer progression

International Journal of Biological Macromolecules, Journal Year: 2023, Volume and Issue: 250, P. 126211 - 126211

Published: Aug. 9, 2023

Language: Английский

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Chemically modified seaweed polysaccharides: Improved functional and biological properties and prospective in food applications

Comprehensive Reviews in Food Science and Food Safety, Journal Year: 2024, Volume and Issue: 23(4)

Published: June 25, 2024

Abstract Seaweed polysaccharides are natural biomacromolecules with unique physicochemical properties (e.g., good gelling, emulsifying, and film‐forming properties) diverse biological activities anticoagulant, antioxidant, immunoregulatory, antitumor effects). Furthermore, they nontoxic, biocompatible biodegradable, abundant in resources. Therefore, have been widely utilized food, cosmetics, pharmaceutical industries. However, their bioactivities sometimes not satisfactory for some purposes. Modification of can impart the amphiphilicity new functions to biopolymers change structure conformation, thus effectively improving functional so as meet requirement targeted applications. This review outlined modification methods representative red algae (carrageenan agar), brown (fucoidan, alginate, laminaran), green (ulvan) that potential food applications, including etherification, esterification, degradation, sulfation, phosphorylation, selenylation, on. The improved modified seaweed applications also summarized.

Language: Английский

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Enhancement of Oral Bioavailability of Protein and Peptide by Polysaccharide-based Nanoparticles

Protein and Peptide Letters, Journal Year: 2024, Volume and Issue: 31(3), P. 209 - 228

Published: March 1, 2024

Abstract: Oral drug delivery is a prevalent and cost-effective method due to its advantages, such as increased absorption surface area improved patient compliance. However, delivering proteins peptides orally remains challenge their vulnerability degradation by digestive enzymes, stomach acids, limited intestinal membrane permeability, resulting in poor bioavailability. The use of nanotechnology has emerged promising solution enhance the bioavailability these vital therapeutic agents. Polymeric NPs, made from natural or synthetic polymers, are commonly used. Natural polysaccharides, alginate, chitosan, dextran, starch, pectin, etc., have gained preference biodegradability, biocompatibility, versatility encapsulating various types. Their hydrophobic-hydrophilic properties can be tailored suit different molecules.

Language: Английский

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Recent biotechnological applications of value-added bioactive compounds from microalgae and seaweeds

Botanical studies, Journal Year: 2024, Volume and Issue: 65(1)

Published: Sept. 23, 2024

Abstract Microalgae and seaweed have been consumed as food for several decades to combat starvation shortages worldwide. The most famous edible microalgae species are Nostoc , Spirulina Aphanizomenon in addition seaweeds, which used traditional medicine food, such Nori, is one of the popular foods containing Pyropia alga a major ingredient. Recently, many applications use algae-derived polysaccharides agar, alginate, carrageenan, cellulose, fucoidan, mannan, laminarin, ulvan, xylan gelling agents pharmaceuticals, cosmetics industries. Moreover, pigments (carotenoids particularly astaxanthins, chlorophylls, phycobilins), minerals, vitamins, polyunsaturated fatty acids, peptides, proteins, polyphenols, diterpenes compounds accumulated under specific cultivation stress conditions algal cells be harvested their biomass feedstock relevant industries applications. No less critical algae bioremediation, thus contributing significantly environmental sustainability. This review will explore discuss various emphasising role recent products with added-value that now on market, novel under-developing bioplastics nanoparticle production. Nonetheless, special attention also drawn towards limitations these technologies applied, how they may overcome.

Language: Английский

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Cardiac tissue engineering: an emerging approach to the treatment of heart failure

Frontiers in Bioengineering and Biotechnology, Journal Year: 2024, Volume and Issue: 12

Published: Aug. 15, 2024

Heart failure is a major health problem in which the heart unable to pump enough blood meet body’s needs. It progressive disease that becomes more severe over time and can be caused by variety of factors, including attack, cardiomyopathy valve disease. There are various methods cure this disease, has many complications risks. The advancement knowledge technology proposed new for diseases. One promising treatments tissue engineering. Tissue engineering field research aims create living tissues organs replace damaged or diseased tissue. goal improve cardiac function reduce need transplantation. This done using three important principles cells, biomaterials signals techniques cells such as electrospinning, hydrogel synthesis, decellularization, etc. diverse. Treating through still under development research, but it hoped there will no transplants invasive surgeries near future. In study, based on most recent years, we examine power treatment failure.

Language: Английский

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Fucoidan dose-dependently alleviated hyperuricemia and modulated gut microbiota in mice

Food & medicine homology., Journal Year: 2025, Volume and Issue: unknown

Published: March 1, 2025

Language: Английский

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Advance of the application of seaweed polysaccharides on antitumor drug delivery systems

International Journal of Pharmaceutics, Journal Year: 2025, Volume and Issue: unknown, P. 125502 - 125502

Published: March 1, 2025

Language: Английский

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Influence of ultrasound extraction of Fucus vesiculosus on the kinetics of fucoidan degradation and its properties

Drug development & registration, Journal Year: 2025, Volume and Issue: unknown

Published: March 28, 2025

Introduction. A promising source for isolating fucoidan is Fucus vesiculosus L., a widespread species of brown algae. In recent years, the possibility using in medicine and pharmacy has been widely studied. The method extracting polysaccharides significantly affects their characteristics properties. To improve extraction efficiency, ultrasonic-assisted (UAE) recently explored. Aim. Study influence time low-frequency UAE algae F. on kinetics degradation its Materials methods. Fresh frozen L. were used as raw material. was carried out at an oscillation frequency 22 kHz temperature 25 °C. extract obtained 60 °C dynamic maceration method. homogeneity molecular weight analyzed by high-performance size exclusion chromatography (HPSEC). FT-IR spectra VERTEX 70 spectrometer. Quantitative determination fucose sulfates performed spectrophotometric antioxidant activity (AOA) assessed FRAP test. Mathematical statistical processing results accordance with Russian Federation Pharmacopeia XV edition MO Excel 2007 software. Results discussion. calculated rate 19.5 %/h. reaction constant half-life second-order model (R 2 > 0.97) 5.8 · 10 –6 mol/(g min) 110 min. Ultrasonic occurred predominantly due to random scission 0,98). Using FTIR spectrometry, it found that preliminary structures without ultrasound after not changed. Analysis showed ultrasonic extraction, despite decrease weight, demonstrated significant vitro. Conclusion. For first time, change conformational properties caused shown. leads average destruction sulfate groups. Overall, this study shows low which gentle, environmentally friendly can be completed short period, effectively critically changing activity.

Language: Английский

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