Chemistry Africa,
Journal Year:
2024,
Volume and Issue:
7(4), P. 1963 - 1980
Published: Jan. 29, 2024
Abstract
Nowadays,
metal
oxide
nanoparticles
(MO
NPs)
are
powerful
tools
for
biological
applications
due
to
their
distinctive
features.
Moreover,
the
efficacy
of
multimetallic
NPs
is
more
fascinating
because
structural
modifications
and
synergistic
effects.
This
study
utilized
one-pot
green
route
fabricate
trimetallic
ZnO-MgO-CuO
(ZMC)
employing
a
greener
reducing
agent
from
Artemisia
abyssinica
leaf
extract
(AALE).
The
crystal
structure,
size,
compositions,
shapes,
external
topology
ZMC
were
characterized
by
Fourier
transform
infrared
(FTIR)
,
UV–Visible
(UV–vis),
X-ray
diffraction
(XRD)
scanning
electron
microscopy
(SEM),
energy-dispersive
(EDX)
transmission
combined
with
selected
area
(TEM/HRTEM-SAED).
outcomes
suggested
that
bio-prepared
highly
crystalline
have
hexagonal
structures
lattice
monoclinic
symmetry
spherical
morphology
average
particle
sizes
14.67
15.13
nm,
respectively
.
Using
MTT
assay,
demonstrated
high
inhibition
percentage
(94.37
±
0.14
at
250
mg/mL)
an
IC
50
value
24.83
mg/mL
MCF-7
cell
lines.
in-vitro
antibacterial
potential
has
been
evaluated
against
four
bacterial
(Gram-positive
Gram-negative)
strains
highest
zone
(35
0.03
mm
)
S.
aureus
strain
lowest
(31
0.11
E.
coli
strain.
also
shown
strong
molecular
binding
interactions
amino
acids
estrogen
receptor
(ERα),
energies
−
9.85,
12.31,
6.04
kcal/mole,
respectively.
Graphical
Archives of Microbiology,
Journal Year:
2023,
Volume and Issue:
205(4)
Published: March 22, 2023
The
utilization
of
living
organisms
for
the
creation
inorganic
nanoscale
particles
is
a
potential
new
development
in
realm
biotechnology.
An
essential
milestone
nanotechnology
process
creating
dependable
and
environmentally
acceptable
metallic
nanoparticles.
Due
to
its
increasing
popularity
ease,
use
ambient
biological
resources
quickly
becoming
more
significant
this
field
study.
phrase
"green
nanotechnology"
has
gained
lot
attention
refers
variety
procedures
that
eliminate
or
do
away
with
hazardous
compounds
repair
environment.
Green
nanomaterials
can
be
used
biotechnological
sectors
such
as
medicine
biology,
well
food
textile
industries,
wastewater
treatment
agriculture
field.
construction
an
updated
level
knowledge
study
systems
might
support
revolutionize
nanoparticles
(NPs)
are
presented
article.
Applied Biochemistry and Biotechnology,
Journal Year:
2022,
Volume and Issue:
195(2), P. 1158 - 1183
Published: Nov. 7, 2022
The
World
Health
Organization
(WHO)
reports
that
the
emergence
of
multidrug-resistant
and
slow
advent
novel
more
potent
antitumor
antimicrobial
chemotherapeutics
continue
to
be
highest
concern
for
human
health.
Additionally,
stability,
low
solubility,
negative
effects
existing
drugs
make
them
ineffective.
Studies
into
alternative
tactics
tackle
such
tenacious
diseases
was
sparked
by
anticancer
antibacterial.
Silver
(Ag)
gold
(Au)
nanoparticles
(NPs)
were
created
from
Trichoderma
saturnisporum,
much
productive
fungal
strain.
Functional
extracellular
enzymes
proteins
carried
out
activities
synthesis
capping
generated
nano-metals.
Characterization
done
on
obtained
Ag-NPs
Au-NPs
through
UV-vis,
FTIR,
XRD,
TEM,
SEM.
versus
methicillin-sensitive
Staphylococcus
aureus
(MSSA)
methicillin-resistant
(MRSA),
Pseudomonas
aeruginosa,
Klebsiella
pneumoniae,
antibacterial
assessed.
In
particular,
effective
against
pathogenic
bacteria
than
Au-NPs.
Furthermore,
antibiofilm
study
shown
had
activity
Ag-NPs.
Interestingly,
applying
DPPH
procedure,
these
noble
metallic
NPs
antioxidant
activity,
in
which
IC50
73.5
μg/mL
190.0
μg/mL,
respectively.
According
cytotoxicity
evaluation
results,
alteration
cells
as
loss
their
typical
shape,
partial
or
complete
monolayer,
granulation,
shrinking,
cell
rounding
with
normal
Vero
693.68
661.24
Au-NPs,
While
cancer
(Mcf7)
370.56
394.79
produced
via
green
have
potential
employed
medical
industry
beneficial
nanocompounds.
Applied Biochemistry and Biotechnology,
Journal Year:
2023,
Volume and Issue:
196(1), P. 85 - 98
Published: April 26, 2023
Abstract
New
and
creative
methodologies
for
the
fabrication
of
silver
nanoparticles
(Ag-NPs),
which
are
exploited
in
a
wide
range
consumer
items,
significant
interest.
Hence,
this
research
emphasizes
biological
approach
Ag-NPs
through
Egyptian
henna
leaves
(
Lawsonia
inermis
Linn.)
extracts
analysis
prepared
Ag-NPs.
Plant
extract
components
were
identified
by
gas
chromatography
mass
spectrometry
(GC-mass).
The
analyses
carried
out
UV–visible
(UV–Vis),
X-ray
diffraction
(XRD),
transmission
electron
microscope
(TEM),
scanning
(SEM),
Fourier
transform
infrared
(FTIR)
analysis.
UV–Vis
reveals
that
have
maximum
peak
at
460
nm
visible
light.
Structural
characterization
recorded
peaks
corresponded
to
Bragg’s
diffractions
nano-crystal,
with
average
crystallite
sizes
varying
from
28
60
nm.
Antibacterial
activities
examined,
it
is
observed
all
microorganisms
very
sensitive
biologically
synthesized
Biomass Conversion and Biorefinery,
Journal Year:
2023,
Volume and Issue:
unknown
Published: Sept. 15, 2023
Abstract
Many
research
papers
are
currently
being
written
about
various
methodologies
for
the
green
synthesis
of
ZnO
nanoparticles.
In
this
study,
nanoparticles
were
prepared
by
method
using
baker’s
yeast
(
Saccharomyces
cerevisiae
).
The
characterization
produced
involved
utilization
XRD,
FTIR,
SEM,
and
TEM.
investigation
assessment
antimicrobial
potential
photocatalytic
degradation
efficacy
synthesized
materials
through
Eriochrome
Black
T
(EBT).
results
indicate
that
exhibit
a
spherical
morphology,
exhibiting
diameters
ranging
from
13.0
to
20.0nm,
with
an
average
particle
size
15.0nm.
against
S.
aureus
)
gram-positive
E.
coli
gram-negative
bacteria
was
tested
conduction
zone
inhibition
(ZOI)
minimum
inhibitory
concentration
(MIC)
tests.
This
focused
on
study
photocatalytic-degradation
EBT
in
presence
ultraviolet
light.
experiments
impact
factors,
such
as
pH
levels,
initial
concentration,
nanocatalyst
dosage,
observed
efficiency.
vitro
ZOI
MIC
assay,
it
(NPs)
exhibited
greater
,
measuring
23.1
mm
0.625
μg/ml.
contrast,
effectiveness
ZnO-NPs
comparatively
lower,
indicated
17.0
1.250μg/ml.
greatest
elimination,
which
achieved
83.0%
equilibrium,
found
employing
20.0mg
NPs
at
3.0,
according
activity
results.
synthetic
powerful
antibacterial
agents
effective
may
be
used
treatment
wastewater.
Journal of Nanobiotechnology,
Journal Year:
2023,
Volume and Issue:
21(1)
Published: Aug. 21, 2023
Abstract
The
gradual
deterioration
of
the
supporting
periodontal
tissues
caused
by
periodontitis,
a
chronic
multifactorial
inflammatory
disease,
is
thought
to
be
triggered
colonization
dysbiotic
plaque
biofilms
in
vulnerable
host.
One
most
prevalent
dental
conditions
world,
periodontitis
now
leading
factor
adult
tooth
loss.
When
does
develop,
it
treated
scraping
mineralized
deposits
and
biofilm
off
surfaces.
Numerous
studies
have
shown
that
non-surgical
treatment
significantly
improves
clinical
microbiological
indices
individuals
with
periodontitis.
Although
parameters
improved,
certain
bacterial
reservoirs
often
persist
on
root
surfaces
even
after
standard
therapy.
Periodontitis
has
been
local
or
systemic
antibiotics
as
well
scaling
planning.
Since
there
aren't
many
brand-new
market,
several
researchers
are
currently
concentrating
creating
alternate
methods
combating
germs.
There
delay
study
subject
nanoparticle
(NP)
toxicity,
which
especially
concerned
mechanisms
action,
while
area
nanomedicine
develops.
promising
them
metal
NPs
since
they
potent
antibacterial
action.
Metal
may
employed
efficient
growth
inhibitors
variety
bacteria,
making
useful
for
In
this
way,
new
contributed
development
anti-inflammatory
platforms
current
therapeutic
effects
metallic
summarized
study.
This
data
might
used
develop
NP-based
alternatives
infections.
Graphical
Frontiers in Nanotechnology,
Journal Year:
2023,
Volume and Issue:
5
Published: May 2, 2023
Biogenic
metallic
nanoparticles
(BMNPs)
are
nanostructure
materials
synthesized
through
biological
processes
that
have
gained
significant
attention
due
to
their
small
size
and
high
surface
area-to-volume
ratio.
BMNPs
several
advantages
over
chemically
ones
eco-friendly
synthesis
regimen,
sustainability,
biocompatibility,
diverse
multifarious
biomedical
applications.
Moreover,
the
superior
cytocompatibility
stability
capping
layer
(MNPs),
reduces
like
hood
of
toxicity
side
effects,
making
them
a
safer
alternative
traditional
drug
delivery
methods.
Among
promising
applications
BMNPs,
antibacterial
activity,
analytical
sensing
heavy
metals,
roles
in
food
preservations
been
widely
explored.
In
addition,
imaging,
also
investigated
for
therapeutic
activity
such
as
antimicrobial
efficacy
against
skin
soft
tissue
nosocomial
pathogens
targeting
cancer
cells
therapy.
The
present
review
bestows
characterization
techniques
involved
with
MNPs
compressive
aspects
biogenic
using
agricultural
materials,
which
cost
minimizes
use
hazardous
chemicals.
focuses
on
multifold
including
biomedical,
analytical,
preservation
food,
other
consumable
goods
toxicological
aspects.
ACS Applied Nano Materials,
Journal Year:
2023,
Volume and Issue:
6(13), P. 10881 - 10902
Published: June 21, 2023
ZnO
nanostructures
(ZnO
NSs)
are
able
to
provide
significant
antimicrobial
activity,
ensuring
high
biocompatibility,
good
chemical
stability,
and
low
toxicity.
Such
versatility
has
led
great
success
of
this
nanomaterial
for
antibacterial,
antifungal,
and,
more
recently,
antiviral
applications.
However,
methods
the
preparation
NSs
must
be
properly
selected
their
end
use.
Moreover,
can
also
cytotoxic
some
extent.
In
context,
review
emphasizes
aspects
relevant
as
well
use
NSs.
particular,
a
brief
overview
sol–gel,
hydrothermal,
biogenic,
electrochemical
approaches
proposed
synthesis
is
presented,
highlighting
advantages/drawbacks
each
route
in
terms
scalability,
simplicity,
efficacy.
Next,
application
several
fields
reported.
This
followed
by
discussion
role
NSs,
where
mechanisms
action,
possible
cell
resistance,
cytotoxicity
highlighted.
We
discuss
against
different
biothreats,
such
bacteria
viruses.
The
future
nanomaterials
field
addressed
final
part.