Functional Mechanism and Clinical Implications of lncRNA LINC-PINT in Delayed Fracture Healing DOI Creative Commons
Xiaoyu Ma, Xin Qian, Rong Ren

et al.

Journal of Investigative Surgery, Journal Year: 2024, Volume and Issue: 37(1)

Published: Oct. 28, 2024

Fracture healing can be impeded or even compromised by various factors, resulting in a growing number of patients suffering. The lncRNA LINC-PINT has garnered attention for its latent role enhancing fracture healing, but specific functions this process remain unclear.

Language: Английский

Saliva, a molecular reflection of the human body? Implications for diagnosis and treatment DOI Creative Commons

Vincent Géli,

Norbert Nabet

Cell Stress, Journal Year: 2024, Volume and Issue: 11, P. 59 - 68

Published: May 27, 2024

For many diseases, and cancer in particular, early diagnosis allows a wider range of therapies better disease management. This has led to improvements diagnostic procedures, most often based on tissue biopsies or blood samples. Other biological fluids have been used diagnose disease, among them saliva offers number advantages because it can be collected non-invasively from large populations at relatively low cost. To what extent might content reveal the presence tumour located distance oral cavity molecular information obtained establish are current questions. review focuses primarily shows how potentially source diagnosis, possibly an stage, for pathologies such as cancers endometriosis.

Language: Английский

Citations

1
Novel insights on oral squamous cell carcinoma management using long non-coding RNAs DOI

Subhayan Sur,

Dimple Davray, Soumya Basu

et al.

Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics, Journal Year: 2024, Volume and Issue: 32(10), P. 1589 - 1612

Published: Jan. 1, 2024

Oral squamous cell carcinoma (OSCC) is one of the most prevalent forms head and neck carcinomas (HNSCC) with a poor overall survival rate (about 50%), particularly in cases metastasis. RNA-based cancer biomarkers are relatively advanced concept, non-coding RNAs currently have shown promising roles detection treatment various malignancies. This review underlines function long (lncRNAs) OSCC its subsequent clinical implications. LncRNAs, class RNAs, larger than 200 nucleotides resemble mRNA numerous ways. However, unlike mRNA, lncRNA regulates multiple druggable non-druggable signaling molecules through simultaneous interaction DNA, RNA, proteins, or microRNAs depending on concentration localization cells. Upregulation oncogenic lncRNAs down-regulation tumor suppressor evident tissues body fluids such as blood saliva indicating their potential valuable biomarkers. Targeted inhibition candidate over-expression showed therapeutic

Language: Английский

Citations

1
Pseudogene GSTM3P1 derived long non-coding RNA promotes ischemic acute kidney injury by target directed microRNA degradation of kidney-protective mir-668. DOI
Qingqing Wei,

Jing Huang,

Man J. Livingston

et al.

Kidney International, Journal Year: 2024, Volume and Issue: 106(4), P. 640 - 657

Published: July 27, 2024

Language: Английский

Citations

1
MicroRNA-205-5p inhibits the growth and migration of breast cancer through targeting Wnt/β-catenin co-receptor LRP6 and interacting with lncRNAs DOI

Sameh H. Mohamed,

Mohamed M. Kamal, Ahmed Reda

et al.

Molecular and Cellular Biochemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 26, 2024

Language: Английский

Citations

1
Functional Mechanism and Clinical Implications of lncRNA LINC-PINT in Delayed Fracture Healing DOI Creative Commons
Xiaoyu Ma, Xin Qian, Rong Ren

et al.

Journal of Investigative Surgery, Journal Year: 2024, Volume and Issue: 37(1)

Published: Oct. 28, 2024

Fracture healing can be impeded or even compromised by various factors, resulting in a growing number of patients suffering. The lncRNA LINC-PINT has garnered attention for its latent role enhancing fracture healing, but specific functions this process remain unclear.

Language: Английский

Citations

1