A Simple and Sensitive Wearable SERS Sensor Utilizing Plasmonic-Active Gold Nanostars

ACS Omega, Journal Year: 2024, Volume and Issue: 9(37), P. 38897 - 38905

Published: Sept. 5, 2024

Wearable sweat sensors hold great potential for offering detailed health insights by monitoring various biomarkers present in sweat, such as glucose, lactate, uric acid, and urea, real time. However, most previously reported sensors, primarily based on electrochemical technology, are limited to only a single analyte at given This study introduces simple, sensitive, wearable patch surface-enhanced Raman spectroscopy (SERS), integrated with highly plasmonically active sharp-branched gold nanostars (GNS) the simultaneous detection of three biomarkers: glucose. We have fabricated GNS commercially available adhesive tape, resulting achieving low-cost, flexible, SERS patch. The limits glucose were achieved 0.7, 0.6, 0.7 μM, respectively, which significantly lower than clinically relevant concentrations these sweat. further evaluated performance our during outdoor activities, including sitting, walking, running. To evaluate its overall effectiveness, we simultaneously measured activities. Overall, sensitive sensor represents significant breakthrough enabling marking major step toward future applications autonomous noninvasive personalized healthcare home.

Language: Английский

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Exploring faradaic and non-faradaic electrochemical impedance spectroscopy approaches in Parkinson's disease diagnosis

Heliyon, Journal Year: 2024, Volume and Issue: 10(5), P. e27433 - e27433

Published: March 1, 2024

Parkinson's disease is a neurodegenerative condition defined by the progressive death of dopaminergic neurons in brain. The diagnosis often uses time-consuming clinical evaluations and subjective assessments. Electrochemical Impedance Spectroscopy (EIS) useful technique for electroanalytical devices due to its label-free performance, in-situ measurements, low cost. development reliable diagnostic tools can be significantly enhanced exploring novel techniques like faradaic non-faradaic EIS detection methods. These have ability identify specific biomarkers or changes electrochemical properties linked disease, allowing an early accurate diagnosis. Faradaic methods utilize redox processes on electrode surface, while rely charge transfer capacitive properties. electrical as indicators measuring impedance at different frequencies. By combining both approaches, it may possible obtain comprehensive understanding occurring patients. This lead more effective potentially opening up new avenues personalized treatment strategies. review explores current research approaches diagnosing using spectroscopy.

Language: Английский

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An overview of electrochemical biosensors used for COVID-19 detection

Analytical Methods, Journal Year: 2024, Volume and Issue: 16(15), P. 2164 - 2176

Published: Jan. 1, 2024

This short review presents the latest advances in field of electrochemical biosensors, focusing particularly on impedimetric biosensors for direct measurement analytes.

Language: Английский

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Electroanalysis overview: additive manufactured biosensors using fused filament fabrication

Analytical Methods, Journal Year: 2024, Volume and Issue: 16(17), P. 2625 - 2634

Published: Jan. 1, 2024

Additive manufacturing (3D-printing), in particular fused filament fabrication, presents a paradigm shift the way electrochemical based biosensing platforms are produced, giving rise to new generation of personalized and on-demand biosensors.

Language: Английский

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Development of paper-based aptasensor for circulating tumor cells detection in the breast cancer

Journal of Electroanalytical Chemistry, Journal Year: 2022, Volume and Issue: 910, P. 116182 - 116182

Published: March 1, 2022

Language: Английский

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