Journal of Translational Medicine,
Journal Year:
2024,
Volume and Issue:
22(1)
Published: May 21, 2024
Abstract
The
Mediterranean
Diet
(MD)
has
garnered
increasing
attention
for
its
potential
protective
effects
against
gastric
cancer
(GC).
MD’s
rich
content
of
antioxidants,
polyphenols,
and
other
bioactive
compounds
contributes
to
ability
modulate
gene
expression,
inhibit
tumor
growth,
regulate
apoptosis.
Studies
have
shown
significant
reductions
in
inflammatory
markers
such
as
C-reactive
protein
(CRP),
necrosis
factor-alpha
(TNF-α),
interleukin-6
(IL-6)
among
individuals
adhering
the
MD,
suggesting
pivotal
role
mitigating
chronic
inflammation-associated
with
development.
Furthermore,
anti-angiogenic
properties,
particularly
components
like
olive
oil,
red
wine,
fish,
tomatoes,
offer
promising
avenues
reducing
GC
risk
by
inhibiting
angiogenesis.
Additionally,
influence
on
intestinal
microbiota
composition
underscores
maintaining
immune
homeostasis
systemic
inflammation,
factors
crucial
prevention.
Despite
challenges
variability
dietary
adherence
scoring
systems
need
further
gender
geographical-specific
studies,
evidence
supports
MD
a
cost-effective
holistic
approach
Emphasizing
nutrition
public
health
is
strategy
broad
implications
global
prevention
initiatives.
Therefore,
this
review
explores
multifaceted
impacts
prevention,
delving
into
anti-inflammatory,
anti-angiogenic,
molecular
mechanisms.
Journal of Innovations in Medical Research,
Journal Year:
2023,
Volume and Issue:
2(3), P. 12 - 23
Published: March 1, 2023
At
present
rising
of
obesity
becomes
a
principal
public
global
health
and
economic
concern.
In
1997,
the
World
Health
Organization
(WHO)
has
declared
as
epidemic.
About
one-third
world
population
is
now
suffering
from
overweight
or
obesity.
It
estimated
that
some
diseases,
such
hypertension,
cardiovascular
Alzheimer
disease,
asthma,
metabolic
syndrome,
liver
steatosis,
gallbladder
osteoarthritis,
obstructive
sleep
apnea,
certain
types
cancer,
hypercholesterolemia,
musculoskeletal
disorders
(joint
muscle
pains),
type
2
diabetes
are
increased
globally
due
to
Obesity
can
affect
nearly
every
organ
system
human
body
even
may
cause
total
heart
failure.
On
other
hand,
incurring
substantial
costs
for
healthcare
already
affected
society.
be
prevented,
avoided,
cured.
Prevention
best
policy,
but
proper
treatment
necessary
who
with
This
article
tries
discuss
aspects
obesity,
causes
prevention
International Microbiology,
Journal Year:
2024,
Volume and Issue:
unknown
Published: April 1, 2024
Abstract
Diet
is
one
of
the
most
important
external
factor
shaping
composition
and
metabolic
activities
gut
microbiome.
The
microbiome
plays
a
crucial
role
in
host
health,
including
immune
system
development,
nutrients
metabolism,
synthesis
bioactive
molecules.
In
addition,
has
been
described
as
critical
for
development
several
mental
disorders.
Nutritional
psychiatry
an
emerging
field
research
that
may
provide
link
between
diet,
microbial
function,
brain
health.
this
study,
we
have
reviewed
influence
different
diet
types,
such
Western,
Mediterranean,
vegetarian,
ketogenic,
on
microbiota
their
implication
various
neuropsychiatric
psychological
Journal of Translational Medicine,
Journal Year:
2024,
Volume and Issue:
22(1)
Published: Jan. 10, 2024
Abstract
Background
Mediterranean
Diet
(MD)
has
many
health
benefits,
particularly
in
reducing
cardiovascular
risk
(CVR).
However,
it
is
still
little
known
if
there
are
any
sex
differences
following
this
nutritional
pattern
and,
thus,
the
potential
sex-related
repercussions
on
CVR
obesity.
The
study
aimed
to
characterize
adherence
MD
and
its
association
with
factors
subjects
Methods
A
total
of
968
females
(33.81
±
11.06
years;
BMI
34.14
7.43
kg/m
2
)
680
males
(aged
34.77
11.31years;
33.77
8.13
were
included
a
cross-sectional
observational
study.
Lifestyle
habits,
anthropometric
parameters,
high
sensitivity
C-reactive
protein
(hs-CRP),
evaluated.
Results
Females
had
significantly
higher
lower
hs-CRP
levels
than
(p
<
0.001).
Additionally,
consumed
more
vegetables,
fruits,
legumes,
fish/seafood,
nuts,
sofrito
sauce
less
quantity
olive
oil,
butter,
cream,
margarine,
red/processed
meats,
soda
drinks
=
0.001),
red
wine,
commercial
sweets
confectionery
their
counterparts.
PREDIMED
score
≤
6
was
associated
increased
both
sexes.
Conclusions
MD,
CVR,
different
food
preferences
males.
Although
same
threshold
been
identified
as
spy
preference
individual
foods
could
explain
impact
Graphical
Current Obesity Reports,
Journal Year:
2025,
Volume and Issue:
14(1)
Published: Jan. 11, 2025
This
narrative
review
explores
the
role
of
Medical
Nutritional
Therapy
(MNT)
in
managing
Metabolic-Associated
Steatotic
Liver
Disease
(MASLD),
previously
known
as
nonalcoholic
fatty
liver
disease.
It
aims
to
examine
effectiveness
specific
nutritional
strategies
preventing
and
treating
this
obesity-linked
Emerging
evidence
underscores
benefits
Mediterranean
diet,
low-carbohydrate
diets,
intermittent
fasting
reducing
fat,
improving
insulin
sensitivity,
mitigating
inflammation.
Supplementing
with
vitamin
E,
omega-3
acids,
silymarin
can
potentially
reduce
fibrosis
promote
health.
MNT
is
a
key
intervention
for
MASLD
management,
emphasizing
dietary
patterns,
caloric
restriction,
nutraceutical
supplementation.
Integrating
these
lifestyle
modifications,
including
regular
physical
activity,
offers
comprehensive
approach
metabolic
outcomes
patients
MASLD.
Further
research
needed
refine
personalize
therapeutic
interventions.
Food and Agricultural Immunology,
Journal Year:
2025,
Volume and Issue:
36(1)
Published: Jan. 16, 2025
The
Very
Low-Energy
Ketogenic
Therapy
(VLEKT)
is
a
structured,
multi-phase
dietary
regimen
characterized
by
carbohydrate
intake
of
less
than
50
g/day
and
daily
caloric
fewer
800
kcal,
which
induces
ketosis
facilitates
significant
weight
loss.
Evidence
suggests
that
this
nutritional
therapy
can
improve
glycemic
control,
lipid
profiles,
blood
pressure,
making
it
promising
option
for
managing
type
2
diabetes
(T2D)
reducing
cardiovascular
risk.
These
benefits
are
achieved
through
reductions
in
triglycerides
low-density
lipoprotein
cholesterol
(LDL-c),
alongside
increases
high-density
(HDL-c).
However,
the
effects
VLEKT
on
metabolism
remain
controversial.
review
emphasizes
urgent
need
further
research
to
validate
long-term
safety
efficacy
VLEKT.
It
also
highlights
critical
role
personalized
plans,
supervised
healthcare
professionals,
optimize
health
outcomes
address
individual
patient
needs.
Molecules,
Journal Year:
2023,
Volume and Issue:
28(3), P. 1365 - 1365
Published: Jan. 31, 2023
Marine
algae
have
excellent
bioresource
properties
with
potential
nutritional
and
bioactive
therapeutic
benefits,
but
studies
regarding
Caulerpa
lentillifera
are
limited.
This
study
aims
to
explore
the
metabolites
profile
antioxidant,
anticancer,
anti-obesity,
in
vitro
cytotoxicity
of
fractionated
ethanolic
extract
C.
using
two
maceration
soxhlet
extraction
methods.
Dried
simplicia
was
mashed
extracted
ethanol
solvent,
concentrated
evaporated,
then
sequentially
partitioned
equal
volumes
ethyl
acetate
n-Hexane.
Six
samples
were
used
this
study,
consisting
ME
(Maceration-Ethanol),
MEA
(Maceration-Ethyl
Acetate),
MH
(Maceration-n-Hexane),
SE
(Soxhletation-Ethanol),
SEA
(Soxhletation-Ethyl
SH
(Soxhletation-n-Hexane).
Non-targeted
metabolomic
profiling
determined
LC-HRMS,
while
anticancer
DPPH
ABTS,
lipase
inhibition,
MTT
assay,
respectively.
demonstrates
that
has
several
functional
metabolites,
antioxidant
capacity
(EC50
is
very
close
EC50
Trolox),
as
well
anti-obesity
<
orlistat,
an
inhibitor
lipid
hydrolyzing
enzymes),
which
useful
precursors
for
new
approaches
improving
obesity-related
diseases.
More
interestingly,
ME,
MH,
novel
agents
drugs,
especially
hepatoma,
breast,
colorectal,
leukemia
cancers.
Finally,
can
be
a
nutraceutical
great
benefits.
Current Nutrition Reports,
Journal Year:
2023,
Volume and Issue:
12(1), P. 56 - 64
Published: Jan. 25, 2023
Abstract
Purpose
of
Review
The
polycystic
ovary
syndrome
(PCOS)
is
an
endocrine
dysfunction
associated
with
a
myriad
metabolic
disorders
and
high
rate
infertility.
In
order
to
aid
its
management,
several
lifestyle/dietary
interventions
have
been
evaluated.
Very
low-calorie
ketogenic
diet
(VLCKD)
rapidly
showing
promising
benefits
not
only
in
obesity
but
also
the
treatment
other
diseases.
main
objective
this
review
assess
scientific
evidence
support
dietary
pattern
as
effective
measure
for
treating
PCOS
it.
Recent
Findings
Preliminary
data
suggested
significant
improvements
body
weight
composition,
profile
(glucose,
serum
insulin,
triglycerides,
total
low-density
lipoprotein
cholesterol),
insulin
resistance
following
VLCKD.
However,
still
scarce
needs
be
more
substantiated.
Summary
Weight
reduction
women
has
shown
improve
derangements
there
no
consensus
on
ideal
or
macronutrient
composition.
There
some
supporting
possible
role
Mediterranean
improving
infertility
(along
well-known
benefits)
PCOS.
Of
note,
VLCKD
might
considered
potential
intervention
short-term
PCOS,
it
must
prescribed
carefully
guided
by
professionals.
International Journal of Molecular Sciences,
Journal Year:
2023,
Volume and Issue:
24(5), P. 4294 - 4294
Published: Feb. 21, 2023
Metabolic
syndrome
is
manifested
by
visceral
obesity,
hypertension,
glucose
intolerance,
hyperinsulinism,
and
dyslipidemia.
According
to
the
CDC,
metabolic
in
US
has
increased
drastically
since
1960s
leading
chronic
diseases
rising
healthcare
costs.
Hypertension
a
key
component
of
associated
with
an
increase
morbidity
mortality
due
stroke,
cardiovascular
ailments,
kidney
disease.
The
pathogenesis
hypertension
syndrome,
however,
remains
poorly
understood.
results
primarily
from
caloric
intake
decreased
physical
activity.
Epidemiologic
studies
show
that
enhanced
consumption
sugars,
form
fructose
sucrose,
correlates
amplified
prevalence
syndrome.
Diets
high
fat
content,
conjunction
elevated
salt
intake,
accelerate
development
This
review
article
discusses
latest
literature
specific
emphasis
on
role
its
stimulatory
effect
absorption
small
intestine
tubules.
Seminars in Cancer Biology,
Journal Year:
2023,
Volume and Issue:
95, P. 103 - 119
Published: Aug. 4, 2023
Olive
oil
(OO)
is
the
main
source
of
added
fat
in
Mediterranean
diet
(MD).
It
a
mix
bioactive
compounds,
including
monounsaturated
fatty
acids,
phytosterols,
simple
phenols,
secoiridoids,
flavonoids,
and
terpenoids.
There
growing
body
evidence
that
MD
OO
improve
obesity-related
factors.
In
addition,
obesity
has
been
associated
with
an
increased
risk
for
several
cancers:
endometrial,
oesophageal
adenocarcinoma,
renal,
pancreatic,
hepatocellular,
gastric
cardia,
meningioma,
multiple
myeloma,
colorectal,
postmenopausal
breast,
ovarian,
gallbladder,
thyroid
cancer.
However,
epidemiological
linking
these
cancers,
their
potential
mechanisms
action,
especially
those
involving
gut
microbiota,
are
not
clearly
described
or
understood.
The
goals
this
review
1)
to
update
current
knowledge
on
associations
between
consumption
2)
identify
microbiota
involved
3)
report
effects
mechanisms.