Normocomplementemic Urticarial Vasculitis Following Influenza Vaccination: A Case Report and Review of the Literature DOI Creative Commons
Yoshihito Mima, Tsutomu Ohtsuka,

Ippei Ebato

et al.

International Medical Case Reports Journal, Journal Year: 2024, Volume and Issue: Volume 17, P. 823 - 829

Published: Sept. 1, 2024

Urticarial vasculitis is characterized by persistent urticarial lesions lasting over 24 h. often triggered medications, infections, and autoimmune disorders. However, vaccinations against viral bacterial pathogens have recently been documented to induce vasculitis. We describe the case of a 67-year-old woman who was presented with an extensive erythematous purpuric rash without systemic symptoms 3 days after influenza vaccination. She diagnosed normocomplementemic based on clinical findings, normal complement levels, histopathological findings leukocytoclastic After receiving oral histamines, she showed complete resolution months Although vaccination-associated common, following rare. reviewed 13 cases wide range vaccines, including those Bacillus Calmette-Guérin, serogroup B meningococcus, influenza, coronavirus disease. conducted comprehensive review various aspects, age, sex, past medical history, type vaccination, number vaccinations, onset time, cutaneous symptoms, place eruption, laboratory disorders, treatment period, Two patients developed hypocomplementemic both experienced such as arthralgia fever. In this review, no significant differences were found in data, which may be attributed small cases. The mechanisms underlying induction vaccines remain unknown; however, addition immune complex deposition activation due vaccine components, molecular mimicry trigger producing vaccine-derived pathogenic antigen antibodies. This study emphasizes need for heightened awareness further investigation rare adverse effect

Language: Английский

Artificial intelligence challenge of discriminating cutaneous arteritis and polyarteritis nodosa based on hematoxylin-and-eosin images of skin biopsy specimens DOI

Wataru Kashiwa,

Kenji Hirata,

Hiroki Endo

et al.

Pathology - Research and Practice, Journal Year: 2025, Volume and Issue: unknown, P. 155915 - 155915

Published: March 1, 2025

Language: Английский

Citations

0
Spontaneous Coronary Dissection Review: A Complex Picture DOI Creative Commons
Mario Bollati,

Vincenzo Ercolano,

Pietro Mazzarotto

et al.

Reviews in Cardiovascular Medicine, Journal Year: 2024, Volume and Issue: 25(12)

Published: Dec. 23, 2024

Spontaneous coronary artery dissection (SCAD) represents a quite rare event but with potentially serious prognostic implications. Meanwhile, SCAD typically presents as an acute syndrome (ACS). Despite the majority of presentation being characterized by typical ACS signs and symptoms, young age at atypical atherosclerotic risk factor profile is responsible for late medical contact misdiagnosis. The diagnostic algorithm similar to that ACS. Low-risk factors prevalence would push toward non-invasive imaging (such computed tomography (CT)); instead, gold standard exam invasive angiography (ICA) due its increased sensitivity disease characterization. Moreover, intravascular (IVI) improves ICA performance, confirming diagnosis clarifying mechanism. A SCAD-ICA classification recognizes four angiographic appearances according lesion extension features (radiolucent lumen, long diffuse narrowing, focal stenosis, vessel occlusion). Concerning management, preferred approach conservative high rates spontaneous healing in first months low rate revascularization success (high complexity percutaneous intervention (PCI) dissection/hematoma risk). Revascularization recommended presence high-risk left main or multivessel involvement, hemodynamic instability, recurrent chest pain, ST elevation). choice PCI; bypass graft (CABG) considered only if PCI not feasible too hazardous operators' centers' experience. Medical therapy includes beta blockers cases ventricular dysfunction; however, no clear data are available about antiplatelet treatment because supposed intramural hematoma enlargement. Furthermore, screening extracardiac arthropathies connective tissue diseases hypothesized association SCAD. Eventually, follow-up important, considering recurrence. Considering patients SCAD, subsequent care essential (including psychological support, also relatives) aim safe complete reintegration into non-limited everyday life.

Language: Английский

Citations

1
COVID-19 associated Cutaneous Polyarteritis nodosa DOI
Milena Mimica,

E. Gutierrez Mora,

Loreto Massardo

et al.

The American Journal of the Medical Sciences, Journal Year: 2024, Volume and Issue: 368(6), P. e67 - e68

Published: July 20, 2024

Language: Английский

Citations

0
Normocomplementemic Urticarial Vasculitis Following Influenza Vaccination: A Case Report and Review of the Literature DOI Creative Commons
Yoshihito Mima, Tsutomu Ohtsuka,

Ippei Ebato

et al.

International Medical Case Reports Journal, Journal Year: 2024, Volume and Issue: Volume 17, P. 823 - 829

Published: Sept. 1, 2024

Urticarial vasculitis is characterized by persistent urticarial lesions lasting over 24 h. often triggered medications, infections, and autoimmune disorders. However, vaccinations against viral bacterial pathogens have recently been documented to induce vasculitis. We describe the case of a 67-year-old woman who was presented with an extensive erythematous purpuric rash without systemic symptoms 3 days after influenza vaccination. She diagnosed normocomplementemic based on clinical findings, normal complement levels, histopathological findings leukocytoclastic After receiving oral histamines, she showed complete resolution months Although vaccination-associated common, following rare. reviewed 13 cases wide range vaccines, including those Bacillus Calmette-Guérin, serogroup B meningococcus, influenza, coronavirus disease. conducted comprehensive review various aspects, age, sex, past medical history, type vaccination, number vaccinations, onset time, cutaneous symptoms, place eruption, laboratory disorders, treatment period, Two patients developed hypocomplementemic both experienced such as arthralgia fever. In this review, no significant differences were found in data, which may be attributed small cases. The mechanisms underlying induction vaccines remain unknown; however, addition immune complex deposition activation due vaccine components, molecular mimicry trigger producing vaccine-derived pathogenic antigen antibodies. This study emphasizes need for heightened awareness further investigation rare adverse effect

Language: Английский

Citations

0