Journal of Drug Delivery Science and Technology, Journal Year: 2025, Volume and Issue: 106, P. 106747 - 106747
Published: Feb. 22, 2025
Language: Английский
Journal of Drug Delivery Science and Technology, Journal Year: 2025, Volume and Issue: 106, P. 106747 - 106747
Published: Feb. 22, 2025
Language: Английский
Processes, Journal Year: 2023, Volume and Issue: 11(9), P. 2617 - 2617
Published: Sept. 2, 2023
Silver nanoparticles, also known as AgNPs, have been extensively researched due to their one-of-a-kind characteristics, including optical, antibacterial, and electrical capabilities. In the era of antibiotics crisis, with an increase in antimicrobial resistance (AMR) a decrease newly developed drugs, AgNPs are potential candidates because substantial activity, limited development, extensive synergistic effect when combined other drugs. The depends on delivery system, compound combination, own properties, such shape size, which heavily influenced by synthesis process. Reduction using chemicals or light, irradiation gamma ray, laser, electron beams microwave biological combination these techniques notable examples AgNP methods. this work, updated methods together strength shortcomings reviewed. Further, factors affecting process discussed. Finally, recent advances challenges considered.
Language: Английский
Citations
106Applied Biochemistry and Biotechnology, Journal Year: 2023, Volume and Issue: 196(6), P. 3636 - 3669
Published: Sept. 5, 2023
Silver nanoparticles (AgNPs) possess unmatched chemical, biological, and physical properties that make them unique compounds as antimicrobial, antifungal, antiviral, anticancer agents. With the increasing drug resistance, AgNPs serve promising entities for targeted therapy against several bacterial, fungal, viral components. In addition, also successful agents cancers, including breast, prostate, lung cancers. Several works in recent years have been done towards development of by using plant extracts like flowers, leaves, bark, root, stem, whole parts. The green method AgNP synthesis thus has advantages over chemical methods, especially low cost synthesis, no toxic byproducts, eco-friendly production pathways, can be easily regenerated, bio-reducing potential derived nanoparticles. Furthermore, are biocompatible do not harm normally functioning human or host cells. This review provides an exhaustive overview synthesized used After a brief introduction, we discussed studies on from different extracts, leaf parts, seeds, stems, plants. following section, highlighted therapeutic actions various bacteria, fungi, viruses, We then general mechanism action AgNPs. methods were article. Finally, concluded providing future perspectives this field nanotechnology.
Language: Английский
Citations
67Hybrid Advances, Journal Year: 2024, Volume and Issue: 6, P. 100184 - 100184
Published: April 21, 2024
Silver nanoparticles are becoming increasingly popular because of their potential applications in bioengineering and medical diagnostics. Nanoparticles possess distinctive features, including increased surface-to-volume ratio superior magnetic properties, which render them well-suited for a range biological uses. They have multi-functionalization, high surface plasmon resonance, large area, stable nature, easy processing. However, silver exciting biomedical applications, biomaterials, detection diagnosis platforms, formulations, drug delivery, device coatings. This typical review provides comprehensive overview the current research on highlighting different methods creating nanoparticles, exploring antimicrobial properties various fields, examining prospective
Language: Английский
Citations
42Heliyon, Journal Year: 2024, Volume and Issue: 10(11), P. e29766 - e29766
Published: May 1, 2024
Nanoparticles have recently become considered as a crucial player in contemporary medicine, with therapeutic uses ranging from contrast agents imaging to carriers for the transport of drugs and genes into specific target. ability more precise molecular interactions human body order target cells tissues minimal adverse effects maximal outcomes. With least number side greatest possible benefit, nanoparticles can particular through body. The majority global public health problems are now treated green synthesized silver (AgNPs), which substantially affect fundamental structure DNA proteins thus display their antimicrobial action. AgNPs inhibit proliferation tumor induce oxidative stress. By inhibiting vascular endothelial growth factor (HIF)-1, pro-inflammatory mediators generated by reduced, mucin hypersecretion is lessened, gene activity subsequently regulated prevent infections. biogenic synthesis (AgNPs) using various plants applications antibacterial, antifungal, antioxidant, anticancer, anti-inflammatory, antidiabetic activities been extensively discussed this article. Also, because only natural substances utilized manufacturing process, particles that created naturally coated, stabilized, play vital role these biomedical actions. characterization AgNPs, possibility preparing AgNPSs different shapes biological method impact on functions toxicities, size, shape other properties toxicity profiles, limitations, future prospects green-mediated also reported study. major goal study provide readers comprehensive, informed, up-to-date summary production methods under-investigational antidiabetic, antifungal anti-inflammatory properties. This review provides instructions suggestions additional studies based AgNPs. evaluation pushes researchers look resources like plant parts create useful nanobiotechnology.
Language: Английский
Citations
26Green Chemistry Letters and Reviews, Journal Year: 2024, Volume and Issue: 17(1)
Published: Feb. 2, 2024
This study aimed to synthesize silver nanoparticles (VJ@AgNPs) using Valeriana jatamansi root extract and assess their antibacterial, antioxidant, antibiofilm properties against Escherichia coli, Staphylococcus aureus, Streptococcus mutans. Various chemical physical characterization methods were employed analyze the synthesized VJ@AgNPs. UV-Visible spectroscopy confirmed presence of VJ@AgNPs with a peak absorption at 426 nm, while FT-IR results indicated involvement phyto-compounds from V. in reduction stabilization these nanoparticles. High-resolution transmission electron microscopy revealed well-dispersed spherical nature an average size 29.1 ± 2.06 X-ray diffraction crystalline structure. The biosynthesized exhibited significant antibacterial activity all tested pathogens, substantial inhibition zones 50 100 μg/mL concentrations. Additionally, displayed potent antioxidant capacity scavenging assays. Furthermore, showed promise photocatalytic degradation, effectively removing 95% RhB dye within 75 minutes under solar light irradiation, following pseudo-first-order kinetics. suggests potential application wastewater treatment for organic removal. biocompatible environmentally friendly underscores as therapeutic agents bacterial infections oxidative stress-related diseases.
Language: Английский
Citations
18European Polymer Journal, Journal Year: 2024, Volume and Issue: 214, P. 113187 - 113187
Published: June 1, 2024
Language: Английский
Citations
16Chemosphere, Journal Year: 2022, Volume and Issue: 310, P. 136759 - 136759
Published: Oct. 10, 2022
Language: Английский
Citations
40Trends in Food Science & Technology, Journal Year: 2023, Volume and Issue: 141, P. 104197 - 104197
Published: Oct. 11, 2023
Language: Английский
Citations
40International Journal of Molecular Sciences, Journal Year: 2022, Volume and Issue: 23(8), P. 4298 - 4298
Published: April 13, 2022
Staphylococcus epidermidis is a bacterium that part of the human microbiota. It most abundant on skin, in respiratory system and digestive tract. Also, aureus contributes to infections has high mortality rate. Both these bacterial species produce biofilm, pathogenic factor increasing their resistance antibiotics. For this reason, we are looking for new substances can neutralize cells. One best-known with such effects silver nanoparticles. They exhibited antibacterial antibiofilm formation activity depended size, shape concentration used. In review, presented data related use nanoparticles counteracting growth biofilm published scientific papers between 2017 2021. Based review experimental results, properties prompt expansion research activity.
Language: Английский
Citations
39ACS Applied Nano Materials, Journal Year: 2023, Volume and Issue: 6(14), P. 12828 - 12848
Published: July 14, 2023
Biofouling is a serious concern and can cause health risks financial burdens in many settings such as maritime structures, medical devices, water treatment plants. Many technologies employing toxic biocides, antifouling coatings, chlorine have been established to prevent or impede biofouling. However, their applications are limited due environmental concerns regarding biocides coating materials. To overcome this, novel coatings ecofriendly, non-toxic nanomaterials appreciable antimicrobial antibiofilm properties developed. Due intrinsic properties, these nanocoatings proven be effective against several water-borne microorganisms. Various nanostructures of metals (silver, copper, gold), metal oxides (zinc oxide, titanium copper cerium oxide), carbon (graphene nanotubes), nanocomposites inhibit the biocorrosion biofilm formation caused by bacteria. Besides, technology developed based on nanocontainers releases key active substances that promote self-cleaning, anticorrosion, properties. This review provides comprehensive overview nanotechnology-enabled agents combat micro- macrofouling phenomena. Moreover, recent progress industrial sectors marine (ships), water-treatment plants, devices elaborated with relevant examples. The mechanistic insights into inhibitory action bacterial cell growth presented. challenges associated developing nanoproducts, practical limitations, prospects also discussed.
Language: Английский
Citations
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