Clinical usefulness of the serum levels of neuroinflammatory and lung fibrosis biomarkers in the assessment of cognitive dysfunction in post-COVID19 patients DOI Creative Commons
Agnieszka Kulczynska‐Przybik, Piotr Czupryna, Justyna Adamczuk

et al.

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: Oct. 28, 2024

Language: Английский

Acute serum protein biomarker profile and prevalence of persistent (>6 months) neuropsychiatric symptoms in a cohort of SARS-CoV-2 PCR positive patients in Cape Town, South Africa. DOI Creative Commons

Inette van Niekerk,

Monica Panieri,

T. Müller

et al.

Brain Behavior & Immunity - Health, Journal Year: 2025, Volume and Issue: unknown, P. 100990 - 100990

Published: April 1, 2025

Language: Английский

Citations

0
Sex-Specific Inflammatory Profiles Affect Neuropsychiatric Issues in COVID-19 Survivors DOI Creative Commons
Mariagrazia Palladini,

Mario Gennaro Mazza,

B. Bravi

et al.

Biomolecules, Journal Year: 2025, Volume and Issue: 15(4), P. 600 - 600

Published: April 18, 2025

Post-COVID syndrome has unveiled intricate connections between inflammation, depressive psychopathology, and cognitive impairment. This study investigates these relationships in 101 COVID-19 survivors, focusing on sex-specific variations. Utilizing path modelling techniques, we analyzed the interplay of a one-month 48-biomarker inflammatory panel, with three-months symptoms performance. The findings indicate that impairment is influenced by both inflammation depression overall cohort. However, prominent differences emerged. In females, lingering imbalance pro- anti-inflammatory responses—likely reflecting long-lasting immune alterations triggered COVID-19—significantly affects functioning shows marginal, though not statistically significant, association symptoms. suggests mixed profile may contribute to outcomes. Conversely, males, was inversely associated severity, protective effects from regulatory mediators (IL-2, IL-4, IL-6, IL-15, LIF, TNF-α, β-NGF) against depression. appeared be driven mainly symptoms, minimal influence markers. These results highlight distinct pathways responses post-COVID-19, potentially shaped endocrine mechanisms. suggest persistent foster long-term neuropsychiatric sequelae, possibly through its brain, underscore need for sex-tailored therapeutic strategies address lasting impact COVID-19.

Language: Английский

Citations

0
Pentraxin 3 promotes microglial M2 polarization and excitatory synapse formation in the hippocampus in depression DOI

Yuhao Xu,

Man Wang, Hong Wei

et al.

International Immunopharmacology, Journal Year: 2024, Volume and Issue: 146, P. 113946 - 113946

Published: Dec. 29, 2024

Language: Английский

Citations

2
Clinical usefulness of the serum levels of neuroinflammatory and lung fibrosis biomarkers in the assessment of cognitive dysfunction in post-COVID19 patients DOI Creative Commons
Agnieszka Kulczynska‐Przybik, Piotr Czupryna, Justyna Adamczuk

et al.

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: Oct. 28, 2024

Language: Английский

Citations

0