Periodontitis in US Adults

The Journal of the American Dental Association, Journal Year: 2018, Volume and Issue: 149(7), P. 576 - 588.e6

Published: June 25, 2018

Language: Английский

---

Diabetes as a potential risk for periodontitis: association studies

Periodontology 2000, Journal Year: 2020, Volume and Issue: 83(1), P. 40 - 45

Published: May 8, 2020

Abstract Diabetes affects one in 10 adults and periodontal disease four the USA, they are linked. Individuals with diabetes more likely to suffer from glycemic control complications of diabetes. The role as a risk factor for other oral conditions will be discussed this review. fact that type 2 diabetes, especially uncontrolled, is has long been recognized. However, 1 gestational recently described. Also, tooth loss described deleterious effects loss, edentulism, comparing diets patients now fully appreciated. From longitudinal studies it clear often precedes periodontitis and, hence, may contribute causal pathway periodontitis. Other manifestations include increased nonoral (vaginal) fungal infections. In there reduced salivary flow associated medications neuropathy affecting glands. This lead caries. Burning mouth, resulting neuropathy, taste impairment also seen. It known delayed wound healing if uncontrolled. Hence, critical achieve good before carrying out surgical procedures or dental implant placement

Language: Английский

---

Association between diabetes mellitus/hyperglycaemia and peri‐implant diseases: Systematic review and meta‐analysis

Journal Of Clinical Periodontology, Journal Year: 2017, Volume and Issue: 44(6), P. 636 - 648

Published: March 27, 2017

Abstract Aim This systematic review investigates whether hyperglycaemia/diabetes mellitus is associated with peri‐implant diseases (peri‐implant mucositis and peri‐implantitis). Materials Methods Electronic manual literature searching was conducted. An a priori case definition for peri‐implantitis used as an inclusion criterion to minimize risk of bias. The Newcastle‐Ottawa Scale quality assessment; random effect models were applied; results reported according the PRISMA Statement. Results Twelve studies eligible qualitative seven them quantitative analyses. Meta‐analyses detected about 50% higher in diabetes than non‐diabetes ( RR = 1.46; 95% CI : 1.21–1.77 OR 1.89; 1.31–2.46; z 5.98; p < .001). Importantly, among non‐smokers, those hyperglycaemia had 3.39‐fold compared normoglycaemia (95% 1.06–10.81). Conversely, association between not statistically significant 0.92; 0.72–1.16 1.06; 0.84–1.27; 1.06, .29). Conclusions Within its limits that demand great caution when interpreting findings, this suggests mellitus/hyperglycaemia greater peri‐implantitis, independently smoking, but mucositis.

Language: Английский

---

Periodontal complications of hyperglycemia/diabetes mellitus: Epidemiologic complexity and clinical challenge

Periodontology 2000, Journal Year: 2018, Volume and Issue: 78(1), P. 59 - 97

Published: Sept. 9, 2018

Abstract This report provides a comprehensive overview of the adverse effects hyperglycemia on periodontium. It combines data from literature reviews original two large, population‐based epidemiologic studies with periodontal health assessment. Emphasis is placed exploration hitherto sparsely reported prediabetes and poorly controlled (uncontrolled) diabetes, in contrast to umbrella term “diabetes.” stems realization that it not simply having diagnosis diabetes may adversely affect health. Rather, level (severity) determining factor, case definition or type question. Importantly, based existing evidence this paper also attempts estimate improvements probing depth clinical attachment can be expected upon successful nonsurgical treatment people chronic periodontitis, without respectively. includes implentation new systematic meta‐analyses allow comparison such intervention outcomes between hyperglycemic normoglycemic subjects. Based both analyses studies, we try answer questions as: Is there glycated hemoglobin concentration threshold for periodontitis risk? Does short‐term reduction gain after scaling root planing depend glycemic control 2 diabetes? Are hyperglycemia/diabetes inferior those Do patients benefit more use adjuvant antibiotics than lead greater tooth loss long‐term post‐periodontal maintenance programs? Throughout review, compare our findings previous whether results these corroborate, are discord with, similar scientific reports literature. We explore potential role dental health‐care professionals helping risk factors identical diabetes. Finally, suggest various topics still need future research.

Language: Английский

---

Lifestyle and periodontitis: The emergence of personalized periodontics

Periodontology 2000, Journal Year: 2018, Volume and Issue: 78(1), P. 7 - 11

Published: Sept. 9, 2018

Abstract Personalized medicine is a medical model that involves the tailoring of healthcare ‐ with decisions, practices, and/or products being customized to an individual patient. In this model, diagnostic testing often employed for selecting appropriate and optimal therapies based on context patient's genetic content or other epidemiologic, sociologic, molecular, physiologic, cellular analyses. With advent major advances in periodontal medicine, including genomic discoveries greater understanding multifactorial nature periodontitis, it seems time ripe use personalized as periodontics. This volume Periodontology 2000 explores how new our periodontitis within can evolve into treatment strategies tailor‐made patients not merely wholesale paradigms.

Language: Английский

---

IDF Diabetes Atlas: Diabetes and oral health – A two-way relationship of clinical importance

Diabetes Research and Clinical Practice, Journal Year: 2019, Volume and Issue: 157, P. 107839 - 107839

Published: Sept. 11, 2019

The current scientific evidence for the bi-directional associations between oral health and diabetes is summarized. universal biologic mechanisms demographic behavioral risk drivers underlying these in both directions are also described. Dysglycemia, even slightly elevated blood sugar levels, adversely affects health, manifesting itself several diseases conditions. In opposite direction, any infection with its subsequent local systemic inflammatory responses glucose levels. Moreover, painful, mobile, or missing teeth may lead to intake of soft food items representing a sub-optimal diet hence poor nutrition, thereby contribute incident type 2 poorer control existing diabetes. Treatment inflammation related conditions, such as non-surgical periodontal treatment extraction infected teeth, can clinically significant decrease Attention infectious referral dental care professionals therefore be an important novel tool medical preventing managing mellitus. Dental detect unrecognized potential dysglycemia refer examination. Such interprofessional, patient centered improved wellbeing, quality life people

Language: Английский

---

Comparisons of Polyexposure, Polygenic, and Clinical Risk Scores in Risk Prediction of Type 2 Diabetes

Diabetes Care, Journal Year: 2021, Volume and Issue: 44(4), P. 935 - 943

Published: Feb. 9, 2021

OBJECTIVE To establish a polyexposure score (PXS) for type 2 diabetes (T2D) incorporating 12 nongenetic exposures and examine whether PXS and/or polygenic risk (PGS) improves prediction beyond traditional clinical factors. RESEARCH DESIGN AND METHODS We identified 356,621 unrelated individuals from the UK Biobank of White British ancestry with no prior diagnosis T2D normal HbA1c levels. Using self-reported hospital admission information, we deployed machine learning procedure to select most predictive robust factors out 111 nongenetically ascertained exposure lifestyle variables in prospective T2D. computed (CRS) PGS by taking weighted sum eight established &gt;6 million single nucleotide polymorphisms, respectively. RESULTS In study population, 7,513 had incident The C-statistics PGS, PXS, CRS models were 0.709, 0.762, 0.839, Individuals top 10% 2.00-, 5.90-, 9.97-fold greater risk, respectively, compared remaining population. Addition improved classification accuracy, continuous net reclassification index 15.2% 30.1% cases, 7.3% 16.9% controls, CONCLUSIONS For T2D, provides modest incremental value over However, concept merits further consideration stratification is likely be useful other chronic disease models.

Language: Английский

---

Periodontitis and incident type 2 diabetes: a prospective cohort study

Journal Of Clinical Periodontology, Journal Year: 2016, Volume and Issue: 44(3), P. 266 - 274

Published: Dec. 30, 2016

Abstract Objectives The aim of this study was to investigate periodontitis as a risk factor for incident type 2 diabetes mellitus (T2DM) in group men aged 58–72 years. Methods One thousand three hundred and thirty‐one dentate, diabetes‐free Northern Ireland underwent detailed periodontal examination during 2001–2003. Follow‐up by bi‐annual questionnaire those reporting their general medical practitioner contacted validate type, treatment diagnosis date. Cox's proportional hazard models were used estimate the effect on diabetes. Multivariable analysis included adjustment various known confounders. Results mean age 63.7 (SD 3.0) There 80 cases (6.0%) T2DM. median period 7.8 years (IQR 6.7–8.3). After adjusting confounding variables, ratio (HR) T2DM with moderate/severe versus no/mild 1.69 (95% CI 1.06–2.69), p = 0.03. Conclusion evidence homogenous dentate men, that moderate severe had significantly increased

Language: Английский

---

Prevalence of diabetes mellitus in people clinically diagnosed with periodontitis: A systematic review and meta‐analysis of epidemiologic studies

Journal Of Clinical Periodontology, Journal Year: 2017, Volume and Issue: 45(6), P. 650 - 662

Published: Nov. 10, 2017

Abstract Objectives Diabetes mellitus and periodontitis are complex chronic diseases with an established bidirectional relationship. This systematic review evaluated in subjects professionally diagnosed the prevalence odds of having diabetes. Methods The MEDLINE ‐PubMed, CENTRAL EMBASE databases were searched. Prevalence diabetes among was extracted or if possible calculated. Results From 803 titles abstracts that came out search, 27 papers met initial criteria. 13.1% 9.6% without periodontitis. Based on subanalysis, for periodontitis, 6.2% when self‐reported, compared to 17.3% clinically assessed. highest observed studies originating from Asian countries (17.2%, n = 18,002) lowest describing populations Europe (4.3%, 7,858). overall ratio patients be as those 2.27 (95% CI [1.90;2.72]). A substantial variability definitions combination self‐reported assessed diabetes, lack confounding control included introduces estimation bias. Conclusions higher within people Self‐reported underestimates this condition clinically. Geographical differences observed: conducted Asia Europe.

Language: Английский

---

Association between diet and periodontitis: a cross-sectional study of 10,000 NHANES participants

American Journal of Clinical Nutrition, Journal Year: 2020, Volume and Issue: 112(6), P. 1485 - 1491

Published: Sept. 2, 2020

Language: Английский

---