Impact of air pollutants on hospital admissions and economic losses of elderly patients with cardiovascular diseases in Southwestern China: A generalized additive model DOI Creative Commons
Shuming Ji, Ni Wu,

Wang Luo

et al.

Sustainable Environment, Journal Year: 2024, Volume and Issue: 10(1)

Published: June 9, 2024

Background In terms of hospitalization risk for the elderly, evidences adverse effects and economic losses air pollutants on different types cardiovascular diseases (CVDs) are limited. This study aims to quantify five major CVDs affected by in Southwestern China.

Language: Английский

Air pollution, coronary artery disease, and cardiovascular events: Insights from the PROMISE trial DOI
Marcel C. Langenbach, Thomas Mayrhofer, I. Langenbach

et al.

Journal of cardiovascular computed tomography, Journal Year: 2025, Volume and Issue: unknown

Published: March 1, 2025

Language: Английский

Citations

1

Is it time to revise the fighting strategy toward type 2 diabetes? Sex and pollution as new risk factors DOI Creative Commons
Michelangela Barbieri, Francesco Prattichizzo, Rosalba La Grotta

et al.

Ageing Research Reviews, Journal Year: 2024, Volume and Issue: 99, P. 102405 - 102405

Published: July 4, 2024

Diabetes mellitus, a metabolic condition affecting around 537 million individuals worldwide, poses significant challenges, particularly among the elderly population. The etiopathogenesis of type 2 diabetes (T2D) depends on combination effects driven by advancing age, genetic background, and lifestyle habits, e.g. overnutrition. These factors influence development T2D differently in men women, with an obvious sexual dimorphism possibly underlying diverse clinical features disease different sexes. More recently, environmental pollution, estimated to cause 9 deaths every year, is emerging as novel risk factor for T2D. Indeed, exposure atmospheric pollutants such PM2.5, O3, NO2, Persistent Organic Pollutants (POP)s, along their bioaccumulation, associated obesity, 15 % excess case very high levels PM2.5. Similar data are available plasticizer molecules, bisphenol A phthalates, endocrine-disrupting chemicals. Even though causality still debated at this stage, preclinical evidence sustains ability multiple affect pancreatic function, promote insulin resistance, alter lipid metabolism, contributing onset progression. In addition, findings suggest possible role also plastic itself pioneeristic studies evidenced that micro- or nanoplastics (MNP)s, particles nano- range, cellular damage, senescence, inflammation, disturbances, leading resistance impaired glucose metabolism animal and/or vitro models. Here we synthesize recent knowledge relative association between air-related plastic-derived incidence T2D, discussing mechanistic links suggested literature. We then anticipate need future field candidate therapeutic strategies limiting pollution-induced damage models, SGLT-2 inhibitors. finally postulate guidelines prevention should consider pollution sex additional limit pandemic.

Language: Английский

Citations

6

Long-term exposure to ambient air pollution and incident gout: A prospective cohort study in the UK Biobank DOI

Anni Li,

Qingli Zhang, Lu Zhou

et al.

Environmental Pollution, Journal Year: 2024, Volume and Issue: 345, P. 123540 - 123540

Published: Feb. 9, 2024

Language: Английский

Citations

4

Global hotspots and trends on environmental exposure and cardiovascular disease from 1999 to 2022 DOI
Xinjie Zhang,

Qing Tan,

Zhengyu Xu

et al.

World Journal of Cardiology, Journal Year: 2025, Volume and Issue: 17(1)

Published: Jan. 21, 2025

BACKGROUND The increasing risk of cardiovascular disease (CVD) associated with worsening environmental exposure is a critical health concern garnering global research attention. AIM To systematically assess the scope and characteristics on relationship between CVD. METHODS A thorough examination publications CVD from 1999 to 2022 was carried out by extensively screening literature using Web Science Core Collection. language selected standardized English. Afterward, different academic tools such as CiteSpace, VOSviewer, HistCite, Python, Matplotlib, Bibliometrix were utilized examine trends in this field. RESULTS study’s findings indicated steady increase scientific among 1640 analyzed documents, peaking 197 publications. United States emerged leading nation regarding high-quality international collaboration. Harvard University identified most prolific institution. “Environmental research” frequently contributing journal, Muenzel T recognized top contributor. Current hotspots are primarily concentrated themes “cardiovascular disease”, “exposure”, “risk”, “mortality”, “air pollution”. CONCLUSION This study highlights link CVD, identifying key exposures diseases while emphasizing need for further investigation into underlying mechanisms.

Language: Английский

Citations

0

The Dark Triad of Particulate Matter, Oxidative Stress and Coronary Artery Disease: What About the Antioxidant Therapeutic Potential DOI Creative Commons
Daniele Grifoni, Elisa Bustaffa, Laura Sabatino

et al.

Antioxidants, Journal Year: 2025, Volume and Issue: 14(5), P. 572 - 572

Published: May 9, 2025

Particulate matter (PM) is a complex mixture of particles with different adverse effects on health, especially the cardiovascular (CV) risk and disease (e.g., increased total CV mortality, ischemic heart disease, failure, stroke, hypertension, dyslipidemia type 2 diabetes). Since oxidative stress (OS) inflammation are main key mechanisms by which PM exerted its biological several inflammatory-related biomarkers have been measured associated PM; abnormalities in these parameters relation to highlight role this relationship terms health effects, including conditions. Antioxidant strategies might prevent/reverse, almost partly, related exposure, addressing OS inflammation, although clinical gain interventional tools not yet clearly demonstrated. This review aims summarize source composition, discussing inflammatory events environmental exposure as mechanistic determinants acute event precipitation. Moreover, modifying potential antioxidants, subjects more susceptible air pollution and/or highly exposed, will be discussed promising research area beyond conventional actually available prevent harmful reduction sources population assessment quality standards) order better face dark triad composed PM, disease.

Language: Английский

Citations

0

The Interplay between Dyslipidemia and Neighboring Developments in Coronary Artery Disease Progression: A Personalized Approach DOI Open Access
Tomasz Urbanowicz, Krzysztof Skotak, Anna Olasińska‐Wiśniewska

et al.

Journal of Personalized Medicine, Journal Year: 2024, Volume and Issue: 14(3), P. 237 - 237

Published: Feb. 23, 2024

(1) Background: Estimates suggest that up to 10% of global annual cardiovascular deaths could be related environmental factors. Not only air pollution components, but also noise exposure and climate changes, are highlighted as nontraditional causes morbidity. The aim this study was identify possible urbanization risk factors for the progression coronary artery disease in a group patients with chronic syndrome. (2) Method: There were 77 (50 (65%) males 27 (35%) females) median age 70 (60–74) years who underwent repetitive angiography due syndrome between 2018 2022. Gensini score calculated assessment advancement. Environmental including neighboring developments taken into account analysis, housing, commercial, industrial within 300, 500, 700 m distances (buffer) from place habitation. (3) Results: multivariable analysis results prediction relation buffer pointed out significance hyperlipidemia (OR: 4.24, 95% CI 1.34–13.39, p = 0.014), initial 1.02, 1.00–1.05, 0.112), neighborhood housing 0.03, 0.01–0.49, 0.025). (4) Conclusions: Hyperlipidemia can regarded use optimal medical therapy.

Language: Английский

Citations

3

Examining the Link between Air Quality (PM, SO2, NO2, PAHs) and Childhood Obesity: A Systematic Review DOI Open Access
Barbara Siewert,

Agata Kozajda,

Marta Jaskulak

et al.

Journal of Clinical Medicine, Journal Year: 2024, Volume and Issue: 13(18), P. 5605 - 5605

Published: Sept. 21, 2024

Background/Objectives: Childhood obesity has emerged as a global health concern with profound implications for long-term outcomes. In recent years, there been increasing interest in the potential role of environmental factors development childhood obesity. This comprehensive review aims to elucidate intricate relationship between various components air pollution and Methods: We systematically analyze existing literature from past 5 years explore mechanistic pathways linking pollution, including particulate matter (PM), nitrogen oxides (NOx), sulfur dioxide (SO2), polycyclic aromatic hydrocarbons (PAHs), systematic examines 33 epidemiological studies on link obesity, published 1 January 2018, 31 2024. Results: Studies counties low overall noticed only no impact exposure unlike countries higher levels suggesting that mitigation pollutants can reduce chance it being negative factor was PM2.5, PM1, PM10, NOx, SO2 but not PAHs, which showed effect children’s across 10 out 11 studies. Conclusions: underscores need interdisciplinary approaches address both socio-economic determinants Efforts aimed at reducing promoting healthy lifestyle behaviors are essential safeguarding well-being children worldwide.

Language: Английский

Citations

3

Association of Air Quality Improvement and Frailty Progression: A National Study across China DOI Creative Commons
Mingqin Liu, Mohammed Zeeshan,

Tiantian Sun

et al.

Toxics, Journal Year: 2024, Volume and Issue: 12(7), P. 464 - 464

Published: June 27, 2024

Accumulating evidence strongly suggests that exposure to ambient air pollution is linked with increased frailty. However, little known about the effect of improved quality on frailty progression. We aimed investigate whether improvements in (PM1, PM2.5, PM10, NO2, and O3) can alleviate progression, particularly aftermath implementation “Clean Air Action” policy China. The study involved 12,891 participants geocoded environmental data from nationwide China Health Retirement Longitudinal Study (CHARLS) during period May 2011 August 2015. Multivariate logistic regression models were used analyze association protective effects noted for PM1, NO2 indices, an aOR (adjusted odds ratio) ranging 0.72 0.79. improvement could progression first examine between frailty, setting a precedent importance clean its impact healthy ageing.

Language: Английский

Citations

1

Impact of air pollutants on hospital admissions and economic losses of elderly patients with cardiovascular diseases in Southwestern China: A generalized additive model DOI Creative Commons
Shuming Ji, Ni Wu,

Wang Luo

et al.

Sustainable Environment, Journal Year: 2024, Volume and Issue: 10(1)

Published: June 9, 2024

Background In terms of hospitalization risk for the elderly, evidences adverse effects and economic losses air pollutants on different types cardiovascular diseases (CVDs) are limited. This study aims to quantify five major CVDs affected by in Southwestern China.

Language: Английский

Citations

0