Air pollution, coronary artery disease, and cardiovascular events: Insights from the PROMISE trial
Journal of cardiovascular computed tomography,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 1, 2025
Language: Английский
Is it time to revise the fighting strategy toward type 2 diabetes? Sex and pollution as new risk factors
Ageing Research Reviews,
Journal Year:
2024,
Volume and Issue:
99, P. 102405 - 102405
Published: July 4, 2024
Diabetes
mellitus,
a
metabolic
condition
affecting
around
537
million
individuals
worldwide,
poses
significant
challenges,
particularly
among
the
elderly
population.
The
etiopathogenesis
of
type
2
diabetes
(T2D)
depends
on
combination
effects
driven
by
advancing
age,
genetic
background,
and
lifestyle
habits,
e.g.
overnutrition.
These
factors
influence
development
T2D
differently
in
men
women,
with
an
obvious
sexual
dimorphism
possibly
underlying
diverse
clinical
features
disease
different
sexes.
More
recently,
environmental
pollution,
estimated
to
cause
9
deaths
every
year,
is
emerging
as
novel
risk
factor
for
T2D.
Indeed,
exposure
atmospheric
pollutants
such
PM2.5,
O3,
NO2,
Persistent
Organic
Pollutants
(POP)s,
along
their
bioaccumulation,
associated
obesity,
15
%
excess
case
very
high
levels
PM2.5.
Similar
data
are
available
plasticizer
molecules,
bisphenol
A
phthalates,
endocrine-disrupting
chemicals.
Even
though
causality
still
debated
at
this
stage,
preclinical
evidence
sustains
ability
multiple
affect
pancreatic
function,
promote
insulin
resistance,
alter
lipid
metabolism,
contributing
onset
progression.
In
addition,
findings
suggest
possible
role
also
plastic
itself
pioneeristic
studies
evidenced
that
micro-
or
nanoplastics
(MNP)s,
particles
nano-
range,
cellular
damage,
senescence,
inflammation,
disturbances,
leading
resistance
impaired
glucose
metabolism
animal
and/or
vitro
models.
Here
we
synthesize
recent
knowledge
relative
association
between
air-related
plastic-derived
incidence
T2D,
discussing
mechanistic
links
suggested
literature.
We
then
anticipate
need
future
field
candidate
therapeutic
strategies
limiting
pollution-induced
damage
models,
SGLT-2
inhibitors.
finally
postulate
guidelines
prevention
should
consider
pollution
sex
additional
limit
pandemic.
Language: Английский
Long-term exposure to ambient air pollution and incident gout: A prospective cohort study in the UK Biobank
Anni Li,
No information about this author
Qingli Zhang,
No information about this author
Lu Zhou
No information about this author
et al.
Environmental Pollution,
Journal Year:
2024,
Volume and Issue:
345, P. 123540 - 123540
Published: Feb. 9, 2024
Language: Английский
Global hotspots and trends on environmental exposure and cardiovascular disease from 1999 to 2022
Xinjie Zhang,
No information about this author
Qing Tan,
No information about this author
Zhengyu Xu
No information about this author
et al.
World Journal of Cardiology,
Journal Year:
2025,
Volume and Issue:
17(1)
Published: Jan. 21, 2025
BACKGROUND
The
increasing
risk
of
cardiovascular
disease
(CVD)
associated
with
worsening
environmental
exposure
is
a
critical
health
concern
garnering
global
research
attention.
AIM
To
systematically
assess
the
scope
and
characteristics
on
relationship
between
CVD.
METHODS
A
thorough
examination
publications
CVD
from
1999
to
2022
was
carried
out
by
extensively
screening
literature
using
Web
Science
Core
Collection.
language
selected
standardized
English.
Afterward,
different
academic
tools
such
as
CiteSpace,
VOSviewer,
HistCite,
Python,
Matplotlib,
Bibliometrix
were
utilized
examine
trends
in
this
field.
RESULTS
study’s
findings
indicated
steady
increase
scientific
among
1640
analyzed
documents,
peaking
197
publications.
United
States
emerged
leading
nation
regarding
high-quality
international
collaboration.
Harvard
University
identified
most
prolific
institution.
“Environmental
research”
frequently
contributing
journal,
Muenzel
T
recognized
top
contributor.
Current
hotspots
are
primarily
concentrated
themes
“cardiovascular
disease”,
“exposure”,
“risk”,
“mortality”,
“air
pollution”.
CONCLUSION
This
study
highlights
link
CVD,
identifying
key
exposures
diseases
while
emphasizing
need
for
further
investigation
into
underlying
mechanisms.
Language: Английский
The Dark Triad of Particulate Matter, Oxidative Stress and Coronary Artery Disease: What About the Antioxidant Therapeutic Potential
Antioxidants,
Journal Year:
2025,
Volume and Issue:
14(5), P. 572 - 572
Published: May 9, 2025
Particulate
matter
(PM)
is
a
complex
mixture
of
particles
with
different
adverse
effects
on
health,
especially
the
cardiovascular
(CV)
risk
and
disease
(e.g.,
increased
total
CV
mortality,
ischemic
heart
disease,
failure,
stroke,
hypertension,
dyslipidemia
type
2
diabetes).
Since
oxidative
stress
(OS)
inflammation
are
main
key
mechanisms
by
which
PM
exerted
its
biological
several
inflammatory-related
biomarkers
have
been
measured
associated
PM;
abnormalities
in
these
parameters
relation
to
highlight
role
this
relationship
terms
health
effects,
including
conditions.
Antioxidant
strategies
might
prevent/reverse,
almost
partly,
related
exposure,
addressing
OS
inflammation,
although
clinical
gain
interventional
tools
not
yet
clearly
demonstrated.
This
review
aims
summarize
source
composition,
discussing
inflammatory
events
environmental
exposure
as
mechanistic
determinants
acute
event
precipitation.
Moreover,
modifying
potential
antioxidants,
subjects
more
susceptible
air
pollution
and/or
highly
exposed,
will
be
discussed
promising
research
area
beyond
conventional
actually
available
prevent
harmful
reduction
sources
population
assessment
quality
standards)
order
better
face
dark
triad
composed
PM,
disease.
Language: Английский
The Interplay between Dyslipidemia and Neighboring Developments in Coronary Artery Disease Progression: A Personalized Approach
Journal of Personalized Medicine,
Journal Year:
2024,
Volume and Issue:
14(3), P. 237 - 237
Published: Feb. 23, 2024
(1)
Background:
Estimates
suggest
that
up
to
10%
of
global
annual
cardiovascular
deaths
could
be
related
environmental
factors.
Not
only
air
pollution
components,
but
also
noise
exposure
and
climate
changes,
are
highlighted
as
nontraditional
causes
morbidity.
The
aim
this
study
was
identify
possible
urbanization
risk
factors
for
the
progression
coronary
artery
disease
in
a
group
patients
with
chronic
syndrome.
(2)
Method:
There
were
77
(50
(65%)
males
27
(35%)
females)
median
age
70
(60–74)
years
who
underwent
repetitive
angiography
due
syndrome
between
2018
2022.
Gensini
score
calculated
assessment
advancement.
Environmental
including
neighboring
developments
taken
into
account
analysis,
housing,
commercial,
industrial
within
300,
500,
700
m
distances
(buffer)
from
place
habitation.
(3)
Results:
multivariable
analysis
results
prediction
relation
buffer
pointed
out
significance
hyperlipidemia
(OR:
4.24,
95%
CI
1.34–13.39,
p
=
0.014),
initial
1.02,
1.00–1.05,
0.112),
neighborhood
housing
0.03,
0.01–0.49,
0.025).
(4)
Conclusions:
Hyperlipidemia
can
regarded
use
optimal
medical
therapy.
Language: Английский
Examining the Link between Air Quality (PM, SO2, NO2, PAHs) and Childhood Obesity: A Systematic Review
Barbara Siewert,
No information about this author
Agata Kozajda,
No information about this author
Marta Jaskulak
No information about this author
et al.
Journal of Clinical Medicine,
Journal Year:
2024,
Volume and Issue:
13(18), P. 5605 - 5605
Published: Sept. 21, 2024
Background/Objectives:
Childhood
obesity
has
emerged
as
a
global
health
concern
with
profound
implications
for
long-term
outcomes.
In
recent
years,
there
been
increasing
interest
in
the
potential
role
of
environmental
factors
development
childhood
obesity.
This
comprehensive
review
aims
to
elucidate
intricate
relationship
between
various
components
air
pollution
and
Methods:
We
systematically
analyze
existing
literature
from
past
5
years
explore
mechanistic
pathways
linking
pollution,
including
particulate
matter
(PM),
nitrogen
oxides
(NOx),
sulfur
dioxide
(SO2),
polycyclic
aromatic
hydrocarbons
(PAHs),
systematic
examines
33
epidemiological
studies
on
link
obesity,
published
1
January
2018,
31
2024.
Results:
Studies
counties
low
overall
noticed
only
no
impact
exposure
unlike
countries
higher
levels
suggesting
that
mitigation
pollutants
can
reduce
chance
it
being
negative
factor
was
PM2.5,
PM1,
PM10,
NOx,
SO2
but
not
PAHs,
which
showed
effect
children’s
across
10
out
11
studies.
Conclusions:
underscores
need
interdisciplinary
approaches
address
both
socio-economic
determinants
Efforts
aimed
at
reducing
promoting
healthy
lifestyle
behaviors
are
essential
safeguarding
well-being
children
worldwide.
Language: Английский
Association of Air Quality Improvement and Frailty Progression: A National Study across China
Mingqin Liu,
No information about this author
Mohammed Zeeshan,
No information about this author
Tiantian Sun
No information about this author
et al.
Toxics,
Journal Year:
2024,
Volume and Issue:
12(7), P. 464 - 464
Published: June 27, 2024
Accumulating
evidence
strongly
suggests
that
exposure
to
ambient
air
pollution
is
linked
with
increased
frailty.
However,
little
known
about
the
effect
of
improved
quality
on
frailty
progression.
We
aimed
investigate
whether
improvements
in
(PM1,
PM2.5,
PM10,
NO2,
and
O3)
can
alleviate
progression,
particularly
aftermath
implementation
“Clean
Air
Action”
policy
China.
The
study
involved
12,891
participants
geocoded
environmental
data
from
nationwide
China
Health
Retirement
Longitudinal
Study
(CHARLS)
during
period
May
2011
August
2015.
Multivariate
logistic
regression
models
were
used
analyze
association
protective
effects
noted
for
PM1,
NO2
indices,
an
aOR
(adjusted
odds
ratio)
ranging
0.72
0.79.
improvement
could
progression
first
examine
between
frailty,
setting
a
precedent
importance
clean
its
impact
healthy
ageing.
Language: Английский
Impact of air pollutants on hospital admissions and economic losses of elderly patients with cardiovascular diseases in Southwestern China: A generalized additive model
Shuming Ji,
No information about this author
Ni Wu,
No information about this author
Wang Luo
No information about this author
et al.
Sustainable Environment,
Journal Year:
2024,
Volume and Issue:
10(1)
Published: June 9, 2024
Background
In
terms
of
hospitalization
risk
for
the
elderly,
evidences
adverse
effects
and
economic
losses
air
pollutants
on
different
types
cardiovascular
diseases
(CVDs)
are
limited.
This
study
aims
to
quantify
five
major
CVDs
affected
by
in
Southwestern
China.
Language: Английский