Journal of Materials Chemistry B,
Journal Year:
2024,
Volume and Issue:
12(11), P. 2795 - 2806
Published: Jan. 1, 2024
Oxidative
stress
and
reactive
oxygen
species
drive
ischemic
stroke
its
related
complications.
New
antioxidant
medications
are
therefore
crucial
for
treating
stroke.
We
developed
Ti2C@BSA-ISO
nanocomposites
loaded
with
the
hydrophobic
drug
isoquercetin
(ISO)
encapsulated
in
BSA
on
Ti2C
nano-enzymes
as
a
novel
therapeutic
nanomedicine
treatment
of
targeting
(ROS).
TEM
visually
proved
successful
preparation
Ti2C@BSA-ISO,
FTIR,
XPS,
zeta
potential
DLS
together
demonstrated
acquisition
Ti2C@BSA-ISO.
In
addition,
enzyme-mimicking
activity
was
evaluated
capacity
verified.
able
to
reverse
decrease
cellular
caused
by
ROS.
Experiments
vivo
showed
that
could
promote
neuroprotection
scavenging
ROS
hippocampal
CA1
area
cerebral
cortex
rats,
thereby
inhibiting
death
alleviating
ischaemic
Specifically,
alleviated
NLRP3/caspase-1/GSDMD
pathway-mediated
pyroptosis.
Our
study
demonstrates
effectiveness
nanomedicines
can
be
directly
used
drugs
synergy
other
drugs,
which
greatly
expands
application
nanomaterials
Small,
Journal Year:
2023,
Volume and Issue:
19(41)
Published: June 8, 2023
Transition
metal
carbide
(Ti3
C2
Tx
MXene),
with
a
large
specific
surface
area
and
abundant
functional
groups,
is
promising
candidate
in
the
family
of
electromagnetic
wave
(EMW)
absorption.
However,
high
conductivity
MXene
limits
its
EMW
absorption
ability,
so
it
remains
challenge
to
obtain
outstanding
attenuation
ability
pure
MXene.
Herein,
by
integrating
HF
etching,
KOH
shearing,
high-temperature
molten
salt
strategies,
layered
(L-MXene),
network-like
nanoribbons
(N-MXene
NRs),
porous
monolayer
(P-MXene
ML),
layer
L)
are
rationally
constructed
favorable
microstructures
states
for
HF,
KOH,
KCl/LiCl
used
functionalize
tune
microstructure
state
(F-
,
OH-
Cl-
terminals),
thereby
improving
capacity
MXene-based
nanostructures.
Impressively,
unique
structure,
proper
electrical
conductivity,
area,
defects,
nanostructures
achieve
good
impedance
matching,
dipole
polarization,
conduction
loss,
thus
inheriting
excellent
performance.
Consequently,
L-MXene,
N-MXene
NRs,
P-MXene
ML,
L
enable
reflection
loss
(RL
)
value
-43.14,
-63.01,
-60.45,
-56.50
dB
matching
thickness
0.95,
1.51,
3.83,
4.65
mm,
respectively.
Nano-Micro Letters,
Journal Year:
2023,
Volume and Issue:
15(1)
Published: April 13, 2023
Abstract
Today,
self-healing
graphene-
and
MXene-based
composites
have
attracted
researchers
due
to
the
increase
in
durability
as
well
cost
reduction
long-time
applications.
Different
studies
focused
on
designing
novel
with
enhanced
sensitivity,
stretchability,
flexibility
improved
electrical
conductivity,
healing
efficacy,
mechanical
properties,
energy
conversion
efficacy.
These
properties
can
be
employed
field
of
wearable
sensors,
supercapacitors,
anticorrosive
coatings,
electromagnetic
interference
shielding,
electronic-skin,
soft
robotics,
etc.
However,
it
appears
that
more
explorations
are
still
needed
achieve
excellent
arbitrary
shape
adaptability,
suitable
adhesiveness,
ideal
durability,
high
immediate
responsibility,
outstanding
features.
Besides,
optimizing
reaction/synthesis
conditions
finding
strategies
for
functionalization/modification
crucial
aspects
should
comprehensively
investigated.
MXenes
graphene
exhibited
superior
electrochemical
abundant
surface
terminations
great
area,
which
important
evolve
biomedical
sensing
stretchability
criteria
need
their
future
Herein,
most
recent
advancements
pertaining
applications
deliberated,
focusing
challenges
perspectives.
Analytical Chemistry,
Journal Year:
2023,
Volume and Issue:
95(44), P. 16383 - 16391
Published: Oct. 26, 2023
The
rational
design
of
efficient
nanozymes
and
the
immobilization
enzymes
are
great
significance
for
construction
high-performance
biosensors
based
on
nano-/bioenzyme
catalytic
systems.
Herein,
a
novel
V-TCPP(Fe)
metal-organic
framework
nanozyme
with
two-dimensional
nanosheet
morphology
is
rationally
designed
by
using
V2CTx
MXene
as
metal
source
iron
tetrakis(4-carboxyphenyl)porphine
(FeTCPP)
ligand
an
organic
linker.
It
exhibits
enhanced
peroxidase-
catalase-like
activities
luminol-H2O2
chemiluminescent
(CL)
behavior.
Based
experimental
theoretical
results,
these
excellent
enzyme-like
derived
from
two-site
synergistic
effect
between
V
nodes
FeTCPP
ligands
in
V-TCPP(Fe).
Furthermore,
confined
system
developed
zeolitic
imidazole
(ZIF)
coencapsulation
bioenzyme.
Using
acetylcholinesterase
(AChE)
model,
our
constructed
V-TCPP(Fe)/AChE@ZIF
was
successfully
used
colorimetric/CL
dual-mode
visual
biosensing
organophosphorus
pesticides.
This
work
expected
to
provide
new
insights
into
systems,
encouraging
applications
catalysis
biosensing.
Nanomaterials,
Journal Year:
2023,
Volume and Issue:
13(2), P. 345 - 345
Published: Jan. 14, 2023
Today,
MXenes
and
their
composites
have
shown
attractive
capabilities
in
numerous
fields
of
electronics,
co-catalysis/photocatalysis,
sensing/imaging,
batteries/supercapacitors,
electromagnetic
interference
(EMI)
shielding,
tissue
engineering/regenerative
medicine,
drug
delivery,
cancer
theranostics,
soft
robotics.
In
this
aspect,
MXene-carbon
nanotube
(CNT)
been
widely
constructed
with
improved
environmental
stability,
excellent
electrical
conductivity,
robust
mechanical
properties,
providing
great
opportunities
for
designing
modern
intelligent
systems
diagnostic/therapeutic,
electronic,
applications.
unique
architectures,
large
specific
surface
areas,
ease
functionalization,
high
conductivity
employed
hybridization
CNTs
superb
heat
fascinating
features.
However,
most
the
studies
centered
around
EMI
catalytic,
sensing
applications;
thus,
need
research
on
biomedical
diagnostic/therapeutic
applications
these
materials
ought
to
be
given
more
attention.
The
photothermal
conversion
efficiency,
selectivity/sensitivity,
stability/recyclability,
biocompatibility/toxicity,
long-term
biosafety,
stimuli-responsiveness
features,
clinical
translation
are
among
crucial
aspects
that
still
comprehensively
investigated.
Although
limited
explorations
focused
MXene-CNT
composites,
future
should
planned
optimization
reaction/synthesis
conditions,
toxicological
evaluations.
Herein,
recent
advancements
pertaining
sensing,
catalysis,
supercapacitors/batteries,
water
treatment/pollutants
removal
highlighted,
focusing
current
trends,
challenges,
outlooks.
