Metal‐Organic Frameworks (MOFs): Classification, Synthesis, Modification, and Biomedical Applications

Small, Journal Year: 2024, Volume and Issue: 20(47)

Published: Aug. 16, 2024

Abstract Metal‐organic frameworks (MOFs) are a new variety of solid crystalline porous functional materials. As an extension inorganic materials, it has made important progress in preparation and application. MOFs widely used various fields such as gas adsorption storage, drug delivery, sensing, biological imaging due to their high specific surface area, porosity, adjustable pore size, abundant active sites, modification by introducing groups. In this paper, the types classified, synthesis methods mechanisms materials summarized. Finally, application prospects challenges metal‐organic framework biomedical field discussed, hoping promote multidisciplinary fields.

Language: Английский

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Nitrogen Vacancy Modulation of Tungsten Nitride Peroxidase-Mimetic Activity for Bacterial Infection Therapy

ACS Nano, Journal Year: 2024, Volume and Issue: 18(35), P. 24469 - 24483

Published: Aug. 22, 2024

Bacterial infections claim millions of lives every year, with the escalating menace microbial antibiotic resistance compounding this global crisis. Nanozymes, poised as prospective substitutes for antibiotics, present a significant frontier in antibacterial therapy, yet their precise enzymatic origins remain elusive. With continuous development nanozymes, applications elemental N-modulated nanozymes have spanned multiple fields, including sensing and detection, infection cancer treatment, pollutant degradation. The introduction nitrogen into not only broadens application range but also holds importance design catalysts biomedical research. synergistic interplay between W N induces pivotal alterations electronic configurations, endowing tungsten nitride (WN) peroxidase-like functionality. Furthermore, vacancies augments nanozyme activity, thus amplifying catalytic potential WN nanostructures. Rigorous theoretical modeling empirical validation corroborate genesis enzyme activity. meticulously engineered nanoflower architecture exhibits an exceptional ability traversing bacterial surfaces, exerting potent bactericidal effects through direct physical interactions. Additionally, topological intricacies these nanostructures facilitate targeting generated radicals on culminating efficacy against both Gram-negative Gram-positive strains along notable inhibition biofilm formation. Importantly, assessments using skin model underscore proficiency nanoflowers effectively clearing fostering wound healing. This pioneering research illuminates realm pseudoenzyme activity capture-killing strategies, promising fertile ground innovative, high-performance artificial peroxidases.

Language: Английский

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A critical review on metal organic frameworks (MOFs)-based sensors for foodborne pathogenic bacteria detection

Talanta, Journal Year: 2024, Volume and Issue: 281, P. 126918 - 126918

Published: Sept. 20, 2024

Language: Английский

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Recent advances on biomedical applications of zirconium-based Nanozymes: A review

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 159464 - 159464

Published: Jan. 1, 2025

Language: Английский

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New horizons for the therapeutic application of nanozymes in cancer treatment

Journal of Nanobiotechnology, Journal Year: 2025, Volume and Issue: 23(1)

Published: Feb. 20, 2025

The advent of nanozymes has revolutionized approaches to cancer diagnosis and therapy, introducing innovative strategies that address the limitations conventional treatments. Nanozyme nanostructures with enzyme-mimicking catalytic abilities exhibit exceptional stability, biocompatibility, customizable functions, positioning them as promising tools for theranostics. By emulating natural enzyme reactions, can selectively target eradicate cells, minimizing harm adjacent healthy tissues. Nanozymes also be functionalized specific targeting ligands, allowing precise delivery regulated release therapeutic agents, improving treatment effectiveness reducing adverse effects. However, issues such selectivity, regulatory compliance remain critical challenges clinical application nanozymes. This review provides an overview nanozymes, highlighting their unique properties, various classifications, activities, diverse applications in strategic oncological deployment could profoundly impact future advancements personalized medicine, recent progress prospective directions enzyme-mimetic treatment. summarizes

Language: Английский

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Nanozyme-assisted CRISPR/Cas systems as an emerging platform for food safety applications: Recent advances

Microchemical Journal, Journal Year: 2025, Volume and Issue: unknown, P. 113270 - 113270

Published: March 1, 2025

Language: Английский

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Target-triggered oxygen vacancy increase of Co3O4 nanoparticles with promoted peroxidase-like activity for specific turn-on colorimetric sensing of uranyl ions

Sensors and Actuators B Chemical, Journal Year: 2024, Volume and Issue: 420, P. 136499 - 136499

Published: Aug. 23, 2024

Language: Английский

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Nano biosensors: Classification, electrochemistry, nanostructures, and optical properties

Results in Engineering, Journal Year: 2024, Volume and Issue: unknown, P. 103428 - 103428

Published: Nov. 1, 2024

Language: Английский

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Biomaterials for Reliable Wearable Health Monitoring: Applications in Skin and Eye Integration

Biomaterials, Journal Year: 2024, Volume and Issue: 314, P. 122862 - 122862

Published: Sept. 30, 2024

Language: Английский

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Carbon-based nanozymes for cancer therapy and diagnosis: A review

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 139704 - 139704

Published: Jan. 1, 2025

Language: Английский

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