Science China Materials, Journal Year: 2024, Volume and Issue: unknown
Published: Nov. 13, 2024
Language: Английский
Science China Materials, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 2, 2025
Language: Английский
Citations
1
Advanced Biology, Journal Year: 2025, Volume and Issue: unknown
Published: Feb. 6, 2025
Abstract Deoxyribonucleic acid (DNA) nanotechnology has brought an unparalleled set of possibilities for self‐assembled structures emerging as independent branch synthetic biology. The field science uses the molecular properties DNA to build nanoparticles and nanodevices that have potential bring breakthroughs in medical science. On one hand, their biocompatibility, precision, ease, programmability make them ideal choice drug delivery healthcare. other, lack proper biodistribution profiles, stability inside system, enzymatic cleavage, immune recognition, translational barriers are some hurdles it faces. Many recent technological advancements progress tackle these challenges, while already been used. These tools technologies need be understood studied successful transition intelligent nanostructures (DNs) healthcare applications. This review thus, highlights challenges being faced by DNs Additionally, provides overview trends using devices disease detection remission finally talks about future scope opportunities effective from bench bedside.
Language: Английский
Citations
1
Angewandte Chemie International Edition, Journal Year: 2024, Volume and Issue: 63(27)
Published: April 24, 2024
Artificial vesicles are recognized as powerful platforms for a large body of research across the disciplines chemistry, physics and biology. Despite great progress, control size distribution to make uniform remains fundamentally difficult due highly uncontrollable growth kinetics, especially micron-sized vesicles. Here we report template-free living self-assembly method prepare monodisperse around 1 μm from an alternating copolymer. The polymer forms nanodisks (ca. 9 nm) in N,N-dimethylformamide (DMF), acting seeds subsequent growth. By adding water, gradually grow into larger circular bilayer nanosheets, which bend crowns continue first-order kinetics well small polydispersity index (<0.1) suggests characteristics. This work paves new way both
Language: Английский
Citations
6
Biomacromolecules, Journal Year: 2024, Volume and Issue: 25(8), P. 4663 - 4676
Published: July 26, 2024
The progression of cancer involves mutations in normal cells, leading to uncontrolled division and tissue destruction, highlighting the complexity tumor microenvironments (TMEs). Immunotherapy has emerged as a transformative approach, yet balance between efficacy safety remains challenge. Nanoparticles such polymersomes offer possibility precisely target tumors, deliver drugs controlled way, effectively modulate antitumor immunity, notably reduce side effects. Herein, stimuli-responsive polymersomes, with capabilities for carrying multiple therapeutics, are highlighted their potential enhancing immunity through mechanisms like inducing immunogenic cell death activating STING (stimulator interferon genes),
Language: Английский
Citations
5
Polymer science & technology., Journal Year: 2025, Volume and Issue: unknown
Published: April 30, 2025
Language: Английский
Citations
0
ACS Applied Nano Materials, Journal Year: 2024, Volume and Issue: 7(13), P. 14865 - 14888
Published: June 28, 2024
Polymersomes have been studied for many years since their discovery, and consistently an appealing widely explored research domain. Their inherent benefits, encompassing stability, versatility, load-carrying capacity, deformability, endow them with opportunities to be used in numerous fields of biomedicine, nanocarriers, diagnostics therapeutics. Nevertheless, shape transformation pathways not comprehensively summarized or received adequate scholarly attention. Herein, we summarize typical mechanisms underlying polymersome self-assembly a particular focus on the associated commonly employed self-assembling methods. Moreover, provide succinct overview proposed applications involving applications, enumerate most recent findings this
Language: Английский
Citations
2
Angewandte Chemie, Journal Year: 2024, Volume and Issue: 136(27)
Published: April 24, 2024
Abstract Artificial vesicles are recognized as powerful platforms for a large body of research across the disciplines chemistry, physics and biology. Despite great progress, control size distribution to make uniform remains fundamentally difficult due highly uncontrollable growth kinetics, especially micron‐sized vesicles. Here we report template‐free living self‐assembly method prepare monodisperse around 1 μm from an alternating copolymer. The polymer forms nanodisks ( ca . 9 nm) in N,N ‐dimethylformamide (DMF), acting seeds subsequent growth. By adding water, gradually grow into larger circular bilayer nanosheets, which bend crowns continue first‐order kinetics well small polydispersity index (<0.1) suggests characteristics. This work paves new way both
Language: Английский
Citations
1
Science China Materials, Journal Year: 2024, Volume and Issue: unknown
Published: Nov. 13, 2024
Language: Английский
Citations
1