Journal of Biomedical Materials Research Part B Applied Biomaterials, Journal Year: 2025, Volume and Issue: 113(5)

Published: May 1, 2025

ABSTRACT Carrageenan (CGN) is a high molecular weight polysaccharide that extracted from red seaweeds. It made up of D‐galactose residues connected by β‐1,4 and α‐1,3 galactose‐galactose bonds. As result its ability to thicken, emulsify, stabilize food, it frequently used as food additive in processed food. Its consumption has surged recent years due the Western diet's (WD) spread. change thickness mucus barrier, composition gut microbiota, innate immune pathway causes inflammation. Also, inherent qualities, which include biodegradability, biocompatibility, resemblance native glycosaminoglycans, antioxidants, anticancer, immunomodulatory, anticoagulant activities, Carrageenan‐based hydrogels have been subject numerous investigations lately for biomedical applications. The brittle hydrogel uncontrollably exchanged ions, however, are two drawbacks application this polysaccharide, but these can be avoided making straightforward chemical changes polymer networks, create chemically bonded with important mechanical characteristics regulated degradation rates. Furthermore, addition diverse kinds nanoparticles, well carrageenan results hybrid platforms noteworthy mechanical, chemical, biological characteristics, qualify them appropriate biomaterials tissue engineering (TE), drug delivery (DD), also wound healing Our goal article provide an overview most current developments carrageenan‐based several modification techniques TE DD

Language: Английский