Cellulose-based aerogels, films, and fibers for advanced biomedical applications

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 497, P. 154434 - 154434

Published: July 31, 2024

Language: Английский

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Fibres—threads of intelligence—enable a new generation of wearable systems

Chemical Society Reviews, Journal Year: 2024, Volume and Issue: 53(17), P. 8790 - 8846

Published: Jan. 1, 2024

Fabrics represent a unique platform for seamlessly integrating electronics into everyday experiences. The advancements in functionalizing fabrics at both the single fibre level and within constructed have fundamentally altered their utility. revolution materials, structures, functionality enables intimate imperceptible integration, rapidly transforming fibres next-generation wearable devices systems. In this review, we explore recent scientific technological breakthroughs smart fibre-enabled fabrics. We examine common challenges bottlenecks physics, chemistry, fabrication strategies, applications that shape future of electronics. propose closed-loop fabric ecosystem encompassing proactive sensing, interactive communication, data storage processing, real-time feedback, energy harvesting, intended to tackle significant technology. Finally, envision computing as sophisticated platforms with system-level attributes management, machine learning, artificial intelligence, intelligent networks.

Language: Английский

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Multifunctional dressings for wound exudate management

Progress in Materials Science, Journal Year: 2024, Volume and Issue: 146, P. 101328 - 101328

Published: June 14, 2024

Language: Английский

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Engineered exosomes and composite biomaterials for tissue regeneration

Theranostics, Journal Year: 2024, Volume and Issue: 14(5), P. 2099 - 2126

Published: Jan. 1, 2024

Exosomes, which are small vesicles enclosed by a lipid bilayer and released many cell types, widely dispersed have garnered increased attention in the field of regenerative medicine due to their ability serve as indicators diseases agents with therapeutic potential. Exosomes play crucial role mediating intercellular communication through transfer biomolecules, including proteins, lipids, RNA, other molecular constituents, between cells. The targeted transport proteins nucleic acids specific cells has potential enhance or impair biological functions. applications, they can be used alone combination approaches. examination unique attributes functions these factors emerged prominent study realm biomedical research. This manuscript summarizes origins properties exosomes, structural, biological, physical, chemical aspects. paper offers complete recent progress tissue repair medicine, emphasizing possible implications methods forthcoming regeneration attempts.

Language: Английский

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Revolutionizing Antimicrobial Biomaterials: Integrating an Enzyme Degradation-Resistant Sequence into Self-Assembled Nanosystems to Overcome Stability Limitations of Peptide-Based Drugs

Advanced Fiber Materials, Journal Year: 2024, Volume and Issue: 6(4), P. 1188 - 1211

Published: May 2, 2024

Language: Английский

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An in situ dressing material containing a multi‐armed antibiotic for healing irregular wounds

Aggregate, Journal Year: 2024, Volume and Issue: 5(3)

Published: Jan. 4, 2024

Abstract Acute and infected wounds resulting from accidents, battlefield trauma, or surgical interventions have become a global healthcare burden due to the complex bacterial infection environment. However, conventional gauze dressings present insufficient contact with irregular lack antibacterial activity against multi‐drug‐resistant bacteria. In this study, we develop in situ nanofibrous tailored fit of various shapes sizes while providing nanoscale comfort excellent properties. Our approach involves fabrication these using handheld electrospinning device that allows for direct deposition nanofiber onto specific wound sites, perfect conformal closure without any mismatch 2 min. The are loaded multi‐armed antibiotics exhibit outstanding Staphylococcus aureus ( S. ) methicillin‐resistant . Compared vancomycin, dressing shows great performance up 98% vitro vivo experiments demonstrate ability prevent infection, greatly alleviate inflammation, promote healing. findings highlight potential personalized clinical applications, including emergency, accident, treatment.

Language: Английский

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Advances in Nanofiber Filtration Membranes: From Principles to Intelligent Applications

Advanced Functional Materials, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 21, 2025

Abstract Air pollution is a silent killer. It poses significant health threat, affecting over 80% of the global population and leading to respiratory cardiovascular diseases. Electrospun nanofiber filtration membranes have made tremendous progress due their large surface areas, adaptable structures, self‐polarizing properties. This review explores recent developments in across four key areas: principles, material design, structural innovations, functionalities. Initially, classical mechanisms discussed, followed by an overview sustainable materials green technologies for advanced filtration. then delve into advancements, highlighting nanofibers with high roughness, ultra‐fine diameters, bimodal distributions. Inspired nature, these innovations led creation high‐performance membranes. Current research focuses on anti‐bacterial antiviral membranes, as well intelligent systems capable sensing physiological signals. Last, existing challenges membrane development, such new mechanisms, preparation technologies, reusable highlighted. anticipated that solutions problems will open up possibilities functional biodegradable smart wearables, upscale healthcare.

Language: Английский

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Electrospun Nanofiber Membranes with Various Structures for Wound Dressing

Materials, Journal Year: 2023, Volume and Issue: 16(17), P. 6021 - 6021

Published: Sept. 1, 2023

Electrospun nanofiber membranes (NFMs) have high porosity and a large specific surface area, which provide suitable environment for the complex dynamic wound healing process number of sites carrying factors. Further, design structure can imitate human dermis, similar to natural extracellular matrix, better promotes hemostasis, anti-inflammatory wounds. Therefore, it has been widely studied in field dressing. This review article overviews development electrospinning technology application electrospun nanofibers dressings. It begins with an introduction history, working principles, transformation electrospinning, focus on selection materials, incorporation functional therapeutic factors, structural membranes. Moreover, wide NFMs containing factors is classified based their special functions, such as antibacterial cell proliferation promotion. also highlights dressing, including porous structures, bead core-shell ordered multilayer membrane structures. Finally, advantages limitations are discussed, challenges faced dressings analyzed promote further research this field.

Language: Английский

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Revolutionizing Wound Healing: Exploring Scarless Solutions through Drug Delivery Innovations

Molecular Pharmaceutics, Journal Year: 2024, Volume and Issue: 21(3), P. 1056 - 1076

Published: Jan. 30, 2024

Human skin is the largest organ and outermost surface of human body, due to continuous exposure various challenges, it prone develop injuries, customarily known as wounds. Although tissue engineering strategies bioactive wound matrices have been employed speed up healing, scarring remains a significant challenge. The environment harsh presence degradative enzymes elevated pH levels, physiological processes involved in regeneration operate on distinct time scales. Therefore, there need for effective drug delivery systems (DDSs) address these issues. objective this review provide comprehensive exposition mechanisms underlying healing process, factors materials used DDSs, different DDSs care. Furthermore, investigation will delve into examination emergent technologies potential avenues enhancing efficacy care devices.

Language: Английский

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Recent Progress in Biomedical Scaffold Fabricated via Electrospinning: Design, Fabrication and Tissue Engineering Application

Advanced Functional Materials, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 26, 2024

Abstract Electrospinning is a significant manufacturing strategy to create micro/nanofiber platforms that can be considered biomedical scaffold for tissue engineering repair and regeneration. In recent years researchers have continuously broadened the equipment design materials development of electrospinning nanofiber (ENPs), which evolved from single‐needle multi‐needle creating 3D ENPs, diversify their application including drugs/cell/growth factors release, anti‐bacterial anti‐inflammatory, hemostasis, wound healing, Herein, multifunctional ENPs with bioactive polymer fabricated via in terms novel material design, construction various structures, requirements different regeneration are reviewed. Furthermore, this review delves into advancements facilitated by highlighting effectiveness versatility across types such as bone, cartilage, tendons, cardiac tissue, nerves. The discussion comprehensively addresses ongoing challenges selection, biodegradation mechanisms, bioactivation strategies, techniques specific applications. Moreover, outlines potential future research avenues aimed at enhancing ENPs‐based approaches engineering. This in‐depth analysis aims provide nuanced insights technical recommendations propel field forward

Language: Английский

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