Materials Today Communications, Journal Year: 2025, Volume and Issue: unknown, P. 112513 - 112513
Published: April 1, 2025
Language: Английский
Materials Today Communications, Journal Year: 2025, Volume and Issue: unknown, P. 112513 - 112513
Published: April 1, 2025
Language: Английский
International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(17), P. 9524 - 9524
Published: Sept. 1, 2024
Core–shell nanostructures are powerful platforms for the development of novel nanoscale drug delivery systems with sustained release profiles. Coaxial electrospinning is facile and convenient creating medicated core–shell elaborate designs which sustained-release behaviors molecules can be intentionally adjusted. With resveratrol (RES) as a model poorly water-soluble cellulose acetate (CA) PVP polymeric carriers, brand-new electrospun nanostructure was fabricated in this study. The guest RES host CA were designed to have reverse gradient distribution within nanostructures. Scanning electron microscope transmission evaluations verified that these nanofibers had linear morphologies, without beads or spindles, an obvious double-chamber structure. X-ray diffraction patterns Fourier transform infrared spectroscopic results indicated involved components highly compatible presented amorphous molecular state. In vitro dissolution tests new structures able prevent initial burst release, extend continuous-release time period, reduce negative tailing-off effect, thus ensuring better profile than traditional blended drug-loaded nanofibers. mechanism underlying influence structure RES/CA on proposed. Based proof-of-concept demonstration, series advanced functional nanomaterials similarly developed based distributions multi-chamber
Language: Английский
Citations
24International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 281, P. 135753 - 135753
Published: Oct. 17, 2024
Language: Английский
Citations
24Polymers, Journal Year: 2024, Volume and Issue: 16(18), P. 2614 - 2614
Published: Sept. 15, 2024
Polymeric composites for manipulating the sustained release of an encapsulated active ingredient are highly sought after many practical applications; particularly, water-insoluble polymers and core–shell structures frequently explored to manipulate behaviors drug molecules over extended time period. In this study, electrospun nanostructures were utilized develop a brand-new strategy tailor spatial distributions both insoluble polymer (ethylcellulose, EC) soluble (polyvinylpyrrolidone, PVP) within nanofibers, thereby extended-release loaded ingredient, ferulic acid (FA). Scanning electron microscopy transmission assessments revealed that all prepared nanofibers had linear morphology without beads or spindles, those from coaxial processes obvious structure. X-ray diffraction attenuated total reflectance Fourier transform infrared spectroscopic tests confirmed FA fine compatibility with EC PVP, presented in amorphous state. vitro dissolution indicated radical (decreasing shell core) PVP (increasing able play their important role elaborately. On one hand, F3 advantages homogeneous composite F1 higher content solutions inhibit initial burst provide longer period release. other F2 core negative tailing-off The key element was water permeation rates, controlled by ratios polymers. new based on structure paves way developing wide variety polymeric heterogeneous realizing desired functional performances.
Language: Английский
Citations
20Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: 506, P. 160117 - 160117
Published: Jan. 1, 2025
Language: Английский
Citations
7Macromolecular Rapid Communications, Journal Year: 2025, Volume and Issue: unknown
Published: Feb. 22, 2025
Abstract Electrospun functional nanofibers enable controlled release of the loaded active ingredient and an adjustable dissolution rate. However, widespread use toxic organic solvents in electrospinning poses risks to human health environment whereas increasing production costs complexity. This article examines application eco‐friendly technologies food engineering, with a focus on water‐based melt methods. It provides detailed analysis water‐soluble biopolymers synthetic polymers, highlighting their current applications challenges engineering. Water‐based is proposed as sustainable alternative, offering scalability reduced environmental impact. transition essential for advancing engineering toward more environmentally responsible practices.
Language: Английский
Citations
2International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: 299, P. 140072 - 140072
Published: Jan. 20, 2025
Language: Английский
Citations
1Nano Energy, Journal Year: 2025, Volume and Issue: unknown, P. 110753 - 110753
Published: Feb. 1, 2025
Language: Английский
Citations
1Polymers, Journal Year: 2025, Volume and Issue: 17(4), P. 542 - 542
Published: Feb. 19, 2025
Flexible sensors are revolutionizing wearable and implantable devices, with conductive hydrogels emerging as key materials due to their biomimetic structure, biocompatibility, tunable transparency, stimuli-responsive electrical properties. However, fragility limited durability pose significant challenges for broader applications. Drawing inspiration from the self-healing capabilities of natural organisms like mussels, researchers embedding self-repair mechanisms into improve reliability lifespan. This review highlights recent advances in (SH) hydrogels, focusing on synthesis methods, healing mechanisms, strategies enhance multifunctionality. It also explores wide-ranging applications, including vivo signal monitoring, biochemical sensors, supercapacitors, flexible displays, triboelectric nanogenerators, bioelectronics. While progress has been made, remain balancing efficiency, mechanical strength, sensing performance. offers insights overcoming these obstacles discusses future research directions advancing SH hydrogel-based bioelectronics, aiming pave way durable, high-performance devices next-generation technologies.
Language: Английский
Citations
1International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: 295, P. 139661 - 139661
Published: Jan. 8, 2025
Language: Английский
Citations
0Nano Energy, Journal Year: 2025, Volume and Issue: unknown, P. 110649 - 110649
Published: Jan. 1, 2025
Language: Английский
Citations
0