Yellow Emissive Carbon Dots – A Robust Nanoprobe for Highly Sensitive Quantification of Jaundice Biomarker and Mitochondria Targeting in Cancer Cells DOI

Kandasamy Sasikumar,

Dhashnamoorthy Subramanian Prabakaran,

Ramar Rajamanikandan

et al.

ACS Applied Bio Materials, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 13, 2024

The abnormally high level of bilirubin (BR) in biofluids (human serum and urine) indicates a probability jaundice liver dysfunction. However, quantification BR as the Jaundice biomarker is difficult due to interference various biomolecules urine. To address this issue, we developed fluorescence-based detection strategy, for which yellow emissive carbon dots (YCDs) were produced from one-step solvothermal process using phloroglucinol thionin acetate chemical precursors. as-fabricated YCDs exhibited strong fluorescence peak at wavelength 542 nm upon excitation 390 nm. We used detecting through turn-off mechanism, unveiling excellent sensitivity linear range 0.5-12.5 μM with limit (LOD) 9.62 nM, was far below clinically relevant range. analytical nanoprobe also offered specificity quantifying real samples. Moreover, biocompatible fluorescent successfully employed target mitochondria live cancer cells. A colocalization study confirmed that possessed ability overlapped completely MitoTracker Red. turned out be straightforward their synthesis, noninvasive, can utilized biomedical sensors diagnose onset well targeting.

Language: Английский

Inner filter effect mediated fluorescent sensing of rutin based on amino acid-derived novel nitrogen and sulfur co-doped carbon dots DOI
Zheng Fang, Xiang Li, Xinan Zhang

et al.

Dyes and Pigments, Journal Year: 2025, Volume and Issue: 236, P. 112684 - 112684

Published: Feb. 1, 2025

Language: Английский

Citations

2
Carbon Quantum Dots: Synthesis, Characteristics, and Quenching as Biocompatible Fluorescent Probes DOI Creative Commons
A. M. Kamal, Seongin Hong, Heongkyu Ju

et al.

Biosensors, Journal Year: 2025, Volume and Issue: 15(2), P. 99 - 99

Published: Feb. 10, 2025

Carbon quantum dots (CQDs), a new class of carbon-based nanomaterials, have emerged as nano-scaled probes with photoluminescence that an eco-friendly and bio-compatible nature. Their cost-efficient synthesis high yields make them indispensable due to their application in opto-electronic devices, including biosensors, bioimaging, environmental monitoring, light sources. This review provides intrinsic properties CQDs such excitation-dependent emission, biocompatibility, quenching properties. Diverse strategies for easy are divided into bottom-up top-down approaches detailed herein. In particular, we highlight luminescence properties, mechanisms could even be utilized the precise rapid detection biomolecules. We also discuss methodologies mitigation fluorescence quenching, which is pivotal biosensors bioimaging.

Language: Английский

Citations

2
Reduction-immobilizing strategy of polymer-embedded sub-2nm Cu nanoparticles with uniform size and distribution responsible for robust catalytic reactions DOI

Rosy Amalia Kurnia Putri,

Wail Al Zoubi,

Bassem Assfour

et al.

Materials Horizons, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 7, 2024

Polymer-embedded metal nanoparticles are in great demand owing to their unique features, leading use various important applications, including catalysis reactions. However, particle sintering and aggregation serious drawbacks, resulting a drastic loss of catalytic activity recyclability. Herein, reduction-immobilizing strategy polymer-embedded sub-2 nm Cu offered highly controlled distribution nanoparticle size within polymer structures with high fidelity. This work sheds light on the performance that rely ultrasmall uniform structures, generating more active sites result efficiency reduction organic compounds. A study was carried out for hydrogenation nitro compounds, achieving nearly 100% an extremely short time remaining stable after 15 consecutive cycles. Furthermore, mechanism demonstrated by density functional theory (DFT) calculations. Notably, discovery this facile may enable remarkable cutting-edge design catalyst materials promising stability.

Language: Английский

Citations

7
Innovative fluorescent nanocomposite eutectogels: Design and characterization towards biosensing applications DOI Creative Commons
Yolanda Alacid,

Raúl Martínez-Baquero,

Rocío Esquembre

et al.

Journal of Molecular Liquids, Journal Year: 2025, Volume and Issue: unknown, P. 127123 - 127123

Published: Feb. 1, 2025

Language: Английский

Citations

0
Green synthesis of multifunctional nitrogen-doped carbon quantum dots (N-CQDs) derived from citrus lemon juice: applications on antioxidant and antimicrobial activities and highly selective detection for Fe3+ ion sensing DOI
Yeduru Venkatesh, Praveen V. Naidu, Podilapu Atchutha Rao

et al.

Research on Chemical Intermediates, Journal Year: 2025, Volume and Issue: unknown

Published: April 9, 2025

Language: Английский

Citations

0
Construction of Cyan Blue Fluorescence Probe based on Nitrogen-Doped Carbon Dots for Detecting Nitrite Ion in Ham Sausage DOI
Zhaochen Liu, Chun Zhu, Guoqing Chen

et al.

Journal of Fluorescence, Journal Year: 2024, Volume and Issue: unknown

Published: June 15, 2024

Language: Английский

Citations

2
Multimodal applications of green carbon dots derived from Potentilla indica (mock strawberry): Antioxidant, antimicrobial, and quenching based quercetin sensor DOI
Neha Sharma, Hae‐Jeung Lee

Journal of environmental chemical engineering, Journal Year: 2024, Volume and Issue: unknown, P. 114216 - 114216

Published: Sept. 1, 2024

Language: Английский

Citations

2
Textile-Based Adsorption Sensor via Mixed Solvent Dyeing with Aggregation-Induced Emission Dyes DOI Open Access

Seong Gyun Hong,

Byeong M. Oh,

Jong H. Kim

et al.

Materials, Journal Year: 2024, Volume and Issue: 17(8), P. 1745 - 1745

Published: April 11, 2024

This study demonstrates a novel methodology for developing textile-based adsorption sensor via mixed solvent dyeing with aggregation-induced emission (AIE) dyes on recycled fabrics. AIE were incorporated into the fabrics using method co-solvent mixture of H2O and organic solvents. imparted unique fluorescence properties to fabrics, altering intensity or wavelength based whether dye molecules in an isolated aggregated state The precise control fraction during was crucial influencing sensing characteristics. These dyed exhibited reactive thermochromic vaporchromic properties, changes corresponding variations temperature exposure volatile solvents (VOCs). Their superior characteristics, including repetitive switching property resistance photo-bleaching, enhance their practicality across various applications. Consequently, smart not only find applications clothing fashion design but demonstrate versatility fields, extending temperature, humidity, hazardous chemicals.

Language: Английский

Citations

1
Yellow Emissive Carbon Dots – A Robust Nanoprobe for Highly Sensitive Quantification of Jaundice Biomarker and Mitochondria Targeting in Cancer Cells DOI

Kandasamy Sasikumar,

Dhashnamoorthy Subramanian Prabakaran,

Ramar Rajamanikandan

et al.

ACS Applied Bio Materials, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 13, 2024

The abnormally high level of bilirubin (BR) in biofluids (human serum and urine) indicates a probability jaundice liver dysfunction. However, quantification BR as the Jaundice biomarker is difficult due to interference various biomolecules urine. To address this issue, we developed fluorescence-based detection strategy, for which yellow emissive carbon dots (YCDs) were produced from one-step solvothermal process using phloroglucinol thionin acetate chemical precursors. as-fabricated YCDs exhibited strong fluorescence peak at wavelength 542 nm upon excitation 390 nm. We used detecting through turn-off mechanism, unveiling excellent sensitivity linear range 0.5-12.5 μM with limit (LOD) 9.62 nM, was far below clinically relevant range. analytical nanoprobe also offered specificity quantifying real samples. Moreover, biocompatible fluorescent successfully employed target mitochondria live cancer cells. A colocalization study confirmed that possessed ability overlapped completely MitoTracker Red. turned out be straightforward their synthesis, noninvasive, can utilized biomedical sensors diagnose onset well targeting.

Language: Английский

Citations

1