Horticulture Research,
Journal Year:
2020,
Volume and Issue:
7(1)
Published: Sept. 19, 2020
Abstract
Reporters
have
been
widely
used
to
visualize
gene
expression,
protein
localization,
and
other
cellular
activities,
but
the
commonly
reporters
require
special
equipment,
expensive
chemicals,
or
invasive
treatments.
Here,
we
construct
a
new
reporter
RUBY
that
converts
tyrosine
vividly
red
betalain,
which
is
clearly
visible
naked
eyes
without
need
of
using
equipment
chemical
We
show
can
be
noninvasively
monitor
expression
in
plants.
Furthermore,
an
effective
selection
marker
for
transformation
events
both
rice
Arabidopsis.
The
will
especially
useful
monitoring
activities
large
crop
plants
such
as
fruit
tree
under
field
conditions
observing
tissue
culture
sterile
conditions.
Biomedicine & Pharmacotherapy,
Journal Year:
2023,
Volume and Issue:
162, P. 114687 - 114687
Published: April 14, 2023
Cancer
is
still
the
leading
cause
of
death
worldwide,
burdening
global
medical
system.
Rosmarinic
acid
(RA)
among
first
secondary
metabolites
discovered
and
it
a
bioactive
compound
identified
in
plants
such
as
Boraginaceae
Nepetoideae
subfamilies
Lamiaceae
family,
including
Thymus
masticmasti
chinaythia
koreana,
Ocimum
sanctum,
Hyptis
pectinate.
This
updated
review
to
highlight
chemopreventive
chemotherapeutic
effects
RA
its
derivatives,
thus
providing
valuable
clues
for
potential
development
some
complementary
drugs
treatment
cancers.
Relevant
information
about
RA's
derivatives
were
collected
from
electronic
scientific
databases,
PubMed/Medline,
Scopus,
TRIP
database,
Web
Science,
Science
Direct.
The
results
studies
showed
numerous
significant
biological
antiviral,
antibacterial,
anti-inflammatory,
anti-tumour,
antioxidant
antiangiogenic
effects.
Most
on
anticancer
with
corresponding
mechanisms
are
experimental
preclinical
stage
missing
evidence
clinical
trials
support
research.
To
open
new
therapeutic
perspectives
future
must
elucidate
molecular
targets
action
more
detail,
human
toxic
adverse
Journal of Agricultural and Food Chemistry,
Journal Year:
2021,
Volume and Issue:
69(5), P. 1496 - 1512
Published: Jan. 29, 2021
This
study
was
designed
to
explore
the
effects
and
discrepancy
of
different
CLA-producing
Bifidobacterium
pseudocatenulatum
on
relieving
colitis
investigate
potential
mechanisms.
B.
MY40C
CCFM680
were
administered
mice
with
DSS-induced
colitis.
The
content
tight
junction
proteins
mucin2
significantly
upregulated.
TNF-α
IL-6
downregulated,
while
IL-10
PPAR-γ
TLR4/NF-κB
pathway
activation
inhibited.
Moreover,
each
treated
strain
increased
Allobaculum
decreased
Sutterella,
Bacteroides,
Oscillospira.
colonic
conjugated
linoleic
acid
(CLA)
concentrations
positively
correlated
effectiveness
in
In
conclusion,
supplementation
alleviated
by
protecting
intestinal
mechanical
barrier,
modulating
gut
microbiota,
blocking
proinflammatory
cytokines,
inhibiting
pathway.
These
results
are
conducive
promote
clinical
trials
product
development
probiotics
for
International Journal of Molecular Sciences,
Journal Year:
2022,
Volume and Issue:
23(1), P. 536 - 536
Published: Jan. 4, 2022
Camellia
oleifera
(Ca.
oleifera)
is
a
woody
tree
species
cultivated
for
the
production
of
edible
oil
from
its
seed.
The
growth
and
yield
tea-oil
trees
are
severely
affected
by
anthracnose
(caused
Colletotrichum
gloeosporioides).
In
this
study,
transcriptomic
metabolomic
analyses
were
performed
to
detect
key
transcripts
metabolites
associated
with
differences
in
susceptibility
between
anthracnose-resistant
(ChangLin150)
susceptible
(ChangLin102)
varieties
Ca.
oleifera.
total,
5001
differentially
expressed
genes
(DEGs)
obtained,
which
479
DEGs
common
resistant
further
analyzed.
KEGG
enrichment
analysis
showed
that
these
significantly
enriched
tyrosine
metabolism,
phenylpropanoid
biosynthesis,
flavonoid
biosynthesis
isoquinoline
alkaloid
pathways.
Furthermore,
68
accumulated
(DAMs)
detected,
including
flavonoids,
such
as
epicatechin,
phenethyl
caffeate
procyanidin
B2.
Comparison
DAMs
revealed
B2
arachidonic
acid
(peroxide
free)
potentially
important.
expression
patterns
involved
confirmed
qRT-PCR.
These
results
suggested
might
play
an
important
role
fight
against
anthracnose.
This
study
provides
valuable
molecular
information
about
response
Co.
gloeosporioides
infection
will
aid
selection
using
marker-assisted
breeding.
Environmental Science & Technology,
Journal Year:
2023,
Volume and Issue:
57(4), P. 1776 - 1787
Published: Jan. 19, 2023
The
biotransformation
behavior
and
toxicity
of
organophosphate
esters
(OPEs)
in
rice
rhizosphere
microbiomes
were
comprehensively
studied
by
hydroponic
experiments.
OPEs
with
lower
hydrophobicity
liable
to
be
translocated
acropetally,
microbiome
could
reduce
the
uptake
translocation
tissues.
New
metabolites
successfully
identified
microbiome,
including
hydrolysis,
hydroxylated,
methylated,
glutathione-,
glucuronide-,
sulfate-conjugated
products.
Rhizobacteria
plants
cooperate
form
a
complex
ecological
interaction
web
for
OPE
elimination.
Furthermore,
active
members
during
degradation
revealed
metagenomic
analysis
indicated
that
most
these
populations
contained
OPE-degrading
genes.
results
metabolomics
analyses
phytotoxicity
assessment
implied
several
key
function
metabolic
pathways
plant
found
perturbed
metabolites,
such
as
diphenyl
phosphate
monophenyl
phosphate.
In
addition,
involved
metabolism
mechanisms,
carbohydrate
metabolism,
amino
acid
synthesis,
nucleotide
Escherichia
coli,
significantly
altered
after
exposure
products
mixture
generated
microbiome.
This
work
first
time
gives
comprehensive
understanding
entire
associated
provides
support
ongoing
risk
emerging
contaminants
and,
critically,
their
transformation
Journal of Agricultural and Food Chemistry,
Journal Year:
2023,
Volume and Issue:
71(24), P. 9243 - 9254
Published: June 12, 2023
Pigments
are
involved
in
many
aspects
of
human
life,
including
food,
cosmetics,
and
textiles.
At
present,
the
pigment
market
is
mainly
occupied
by
synthetic
pigments.
However,
pigments
have
gradually
presented
safety
environmental
problems.
Therefore,
humans
begun
to
focus
on
use
natural
In
contrast
extraction
from
plants
animals,
production
microbial
fermentation
not
affected
season
region.
This
review
highlights
recent
advances
synthesis
pigments,
classifying
them
into
various
groups,
flavonoids,
isoprenoids,
porphyrins,
N-heterocyclics,
polyketides,
others.
The
biosynthetic
pathways
for
each
group
elucidated
along
with
latest
progress
made
enhancing
efficiency
both
non-natural
microorganisms.
Additionally,
challenges
associated
economically
producing
using
microorganisms
also
discussed.
provides
a
reference
researchers
replace
Physiologia Plantarum,
Journal Year:
2025,
Volume and Issue:
177(1)
Published: Jan. 1, 2025
Abstract
Halophytes
display
distinctive
physiological
mechanisms
that
enable
their
survival
and
growth
under
extreme
saline
conditions.
This
makes
them
potential
candidates
for
use
in
agriculture.
In
this
research,
tomato
(
Solanum
lycopersium
Mill.)
was
cultivated
moderately
conditions
two
different
managements
involving
Arthrocaulon
macrostachyum
L.,
a
salt
accumulator
shrub:
intercropping,
i.e.
,
co‐cultivation
of
tomato/halophyte;
crop
rotation,
which
is
grown
where
the
halophyte
previously
cultivated.
The
effect
these
evaluated
plants
comparison
with
monoculture,
regards
to
biochemical
variables
metabolomic
proteomic
profiles.
Both
halophyte‐based
reduced
soil
salinity.
Crop
rotation
enhanced
photosynthesis
protective
at
photosynthetic
level.
addition,
both
altered
hormone
profile
antioxidant
capacity,
whereas
reactive
oxygen
species
over‐accumulation
leaf
tissues
indicated
establishment
controlled
mild
oxidative
stress.
However,
production
remained
unchanged.
Metabolomic
approaches
suggest
complex
interactions
level,
driven
by
influence
halophyte.
regard,
an
interplay
ROS/lipid‐based
signalling
pathways
proposed.
Moreover,
improved
associated
accumulation
sugar
metabolism‐related
compounds
photosynthesis‐related
proteins.
Likewise,
acylamino
acid‐releasing
enzymes,
class
serine‐proteases,
remarkably
increased
managements,
may
act
modulate
capacity
plants.
summary,
work
reveals
common
patterns
intercropping
halophyte,
supporting
A.
farming
systems.
Nature Communications,
Journal Year:
2025,
Volume and Issue:
16(1)
Published: Jan. 21, 2025
Echinacoside
(ECH),
one
of
the
most
representative
phenylethanoid
glycosides
(PhGs),
has
considerable
neuroprotective
effects
and
is
an
effective
ingredient
in
numerous
commercial
drugs.
Here,
we
elucidate
complete
ECH
biosynthetic
pathway
medicinal
plant
Cistanche
tubulosa.
In
total,
14
related
genes
are
cloned
functionally
characterized.
Two
upstream
pathways
for
tyrosol
biosynthesis
from
L-tyrosine
identified:
includes
separate
decarboxylation,
deamination
reduction
steps;
other
uses
microbial-like
transamination,
decarboxylation
steps.
addition,
a
distinct
downstream
assembly
process
to
revealed
that
sequential
glucosylation,
acylation,
hydroxylation,
rhamnosylation
form
acteoside,
ends
with
final
glucosylation
converting
acteoside
ECH.
Furthermore,
de
novo
synthesis
23
PhG
derivatives
achieved
via
heterologous
expression
different
combinations
functional
tobacco.
Our
findings
provide
insights
into
platform
alternative
production
complex
PhGs.
(ECH)
(PhGs)
responsible
bioactivities
traditional
Chinese
medicine
Herba.
authors
tubulosa
synthesize
PhGs
