Current Opinion in Psychiatry, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 17, 2024

Purpose of review Using advanced bibliometric analysis, we systematically mapped the most current literature on urban air pollution and neurodevelopmental conditions to identify key patterns associations. Here, findings from broader by discussing a distilled, validated subset 44 representative studies. Recent Literature highlights complex relationship between environmental toxins, disorders in children, neurobehavioral pathways involving oxidative stress, neuroinflammation, protein aggregation. Chronic prenatal postnatal exposure airborne pollutants – such as particulate matter heavy metals may contribute early formation amyloid plaques through preadolescence. These processes compromise synaptic plasticity neural integrity, which can progressively induce cognitive, emotional, behavioral dysregulation, sharing some pathological features traditionally associated with adult neurodegenerative diseases. Summary The interactions levels, developmental timing, factors genetic vulnerability are still undetermined. However, accelerated leading cognitive decline suboptimal mental health children adolescents seem likely linked penetrating blood–brain barrier, inducing stress neuroinflammation. Urgent precautionary action might reduce exposures during critical periods, thereby safeguarding children's function health.

Language: Английский