Cited by The literature of heterocyclic chemistry, Part XX, 2020

Electrochemical Synthesis and Reactivity of Three‐Membered Strained Carbo‐ and Heterocycles DOI

Rakesh Kumar,

Nakshatra Banerjee,

Pankaj Kumar

et al.

Chemistry - A European Journal, Journal Year: 2023, Volume and Issue: 29(57)

Published: July 12, 2023

Three-membered carbocyclic and heterocyclic ring structures are versatile synthetic building blocks in organic synthesis with biological importance. Moreover, the inherent strain of these three-membered rings leads to their ring-opening functionalization through C->C, C->N, C-O bond cleavage. Traditional methods for molecules require use acid catalysts or transition metals. Recently, electro-organic has emerged as a powerful tool initiating new chemical transformations. In this review, mechanistic aspects electro-mediated carbo- heterocycles highlighted.

Language: Английский

Citations

Asymmetric Catalytic (2+1) Cycloaddition of Thioketones to Synthesize Tetrasubstituted Thiiranes DOI

Xiaobin Lin, Maoping Pu, Xinpeng Sang

et al.

Angewandte Chemie International Edition, Journal Year: 2022, Volume and Issue: 61(19)

Published: Feb. 26, 2022

Herein, we report the first example of enantioselective (2+1) cycloaddition thioketones with α-diazo pyrazoleamides for direct synthesis tetrasubstituted thiiranes. In presence chiral N,N'-dioxide/cobalt(ΙΙ) complexes (2-5 mol%), excellent efficiency (up to 99 % yield within 15 mins) and high stereoselectivity >19 : 1 dr 97 ee) are available. Elaborations thiiranes via desulfuration have also been conducted deliver olefins. Density functional theory calculations reveal that reaction initiates from a doublet state cobalt(ΙΙ) carbenoid, which is followed by quartet cobalt(ΙΙ)-bound thiocarbonyl ylide pathway. This work provides route selective construction olefins otherwise difficult access.

Language: Английский

Citations

The microwave-assisted syntheses and applications of non-fused single-nitrogen-containing heterocycles DOI

Jay Prakash Soni,

Krishna Sowjanya Chemitikanti,

Swanand Vinayak Joshi

et al.

Organic & Biomolecular Chemistry, Journal Year: 2020, Volume and Issue: 18(48), P. 9737 - 9761

Published: Jan. 1, 2020

Microwave technology has emerged as a great tool for the efficient synthesis of organic compounds and it provides opportunities chemists to achieve chemical transformations that tend be challenging using classical approaches. Additionally, N-heterocycles are well-known their medicinal/biological significance, along with applications excellent building blocks in synthesis. The dominance drug molecules other pharmacological agents makes them attractive scaffolds, which encourages develop wide range strategies towards greener functionalization these heterocycles. In this regard, we have collated discussed literature relating microwave-assisted modification non-(benzo)fused single-nitrogen-containing from past decade. role microwave technique its benefits over conventional approach also been emphasized terms overall reaction efficiency, time, yield, reduced side-product generation, neat clean reactions, chemo-/regio-/enantio-selectivity, use mild reagents/reaction conditions objectives green sustainable chemistry.

Language: Английский

Citations

Kinetics of the Diels–Alder Reaction of Thiofluorenone with 9,10-Dimethylanthracene DOI

Dmitry A. Kornilov, А. Г. Мустафин

Russian Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 60(4), P. 601 - 605

Published: April 1, 2024

Language: Английский

Citations

Asymmetric Catalytic (2+1) Cycloaddition of Thioketones to Synthesize Tetrasubstituted Thiiranes DOI

Xiaobin Lin, Maoping Pu, Xinpeng Sang

et al.

Angewandte Chemie, Journal Year: 2022, Volume and Issue: 134(19)

Published: Feb. 26, 2022

Abstract Herein, we report the first example of enantioselective (2+1) cycloaddition thioketones with α‐diazo pyrazoleamides for direct synthesis tetrasubstituted thiiranes. In presence chiral N,N′ ‐dioxide/cobalt(ΙΙ) complexes (2–5 mol%), excellent efficiency (up to 99 % yield within 15 mins) and high stereoselectivity >19 : 1 dr 97 ee) are available. Elaborations thiiranes via desulfuration have also been conducted deliver olefins. Density functional theory calculations reveal that reaction initiates from a doublet state cobalt(ΙΙ) carbenoid, which is followed by quartet cobalt(ΙΙ)‐bound thiocarbonyl ylide pathway. This work provides route selective construction olefins otherwise difficult access.

Language: Английский

Citations

The literature of heterocyclic chemistry, Part XX, 2020 DOI

Л. И. Беленький,

Галина А. Газиева, Yu. B. Evdokimenkova

et al.

Advances in heterocyclic chemistry, Journal Year: 2022, Volume and Issue: unknown, P. 201 - 274

Published: Nov. 30, 2022

Language: Английский

Citations