The association between adult IgA vasculitis and cancer: a prospective observational study

Frontiers in Medicine, Journal Year: 2025, Volume and Issue: 12

Published: Feb. 25, 2025

Cancer has been reported as a potential trigger for IgA vasculitis (IgAV) in adults; however, data on this topic are scarce. The aim of our study was to examine the frequency and location cancer adults with IgAV. We included 295 IgAV patients diagnosed between January 2010 June 2021 followed at secondary/tertiary rheumatology centre. episodes were recorded classified into three groups according their temporal relation IgAV: (1) prior IgAV; (2) concurrently (3) during follow-up. term associated (IgAV-CA) used cases presenting while active or within three-year period before after diagnosis. Forty-seven (15.9%) developed total 56 different cancers. Of these, 43 cancers (76.8%) preceded diagnosis, 3 (5.3%) IgAV, 10 (17.9%) Twenty-two (7.5%) who 24 (42.9%) could be IgAV-CA cases. most frequently group prostatic, renal bladder cancer, together accounting 50% Age smoking concurrent cancers, arthritis represented risk factor development represent 7% adult In elderly patients, careful examination urogenital tract is warranted when suspected.

Language: Английский

Hematopoietic stem cell conditioned media induces apoptosis in colorectal cancer stem cells via dysregulation of HSP90 and 26S proteasome system

The International Journal of Biochemistry & Cell Biology, Journal Year: 2025, Volume and Issue: unknown, P. 106773 - 106773

Published: April 1, 2025

Language: Английский