Intense fluorescence of air-stable sodium diarylformamidinate: effective control with a novel electron-withdrawing 4-cyano-3,5-bis(trifluoromethyl)phenyl group DOI
Kenichi Michigami,

Daiki Kawakami,

I. Ueda

et al.

Journal of Materials Chemistry C, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 19, 2024

4-Cyano-3,5-bis(trifluoromethyl)phenyl N -substituents significantly enhanced stability toward air and fluorescence of formamidinate salts ( Φ up to 91%). DFT studies suggested the locally excited state derived emission from amidinate anions.

Language: Английский

Progress in Photocatalytic Degradation of Industrial Organic Dye by Utilising the Silver doped Titanium Dioxide Nanocomposite. DOI Creative Commons
Vinayak Nikam,

Chin Wei Lai,

Mohd Rafie Johan

et al.

Heliyon, Journal Year: 2024, Volume and Issue: 10(24), P. e40998 - e40998

Published: Dec. 1, 2024

Industrial organic dyes represent a significant portion of pollutants discharged into the environment, particularly by textile industry. These compounds pose serious threats to living organisms due their high toxicity. Various techniques have been explored for degradation dyes, among which heterogeneous photocatalysis utilising titanium dioxide (TiO

Language: Английский

Citations

11

Advances in Organic Fluorescent and Colorimetric Probes for The Detection of Cu 2+ and Their Applications in Cancer Cell Imaging (2020–2024) DOI
Alaa Shafie, Amal Adnan Ashour

Critical Reviews in Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 27

Published: Jan. 21, 2025

Organic fluorescence and colorimetric probes have emerged as vital tools for detecting metal ions, due to their high sensitivity, selectivity, rapid response times. Copper, an essential trace element, plays a critical role in biological systems, yet its imbalance can lead severe disorders such neurodegenerative diseases, cancer, Wilson's disease. Over the past few years, advancements probe design unlocked innovative avenues not only Cu2+ environmental samples but also visualizing distribution through imaging. These offering robust performance under diverse conditions. Fluorescence imaging using these pivotal cancer diagnosis, prognosis, treatment monitoring by real-time visualization of tumor morphology biomolecular interactions at cellular tissue levels. This review aims explore diversity organic developed detection Cu2+, with particular focus on applications from 2020 2024. The discussion highlights use various cells SiHa, HCT 116, GES-1, RAW 264.7, HepG2, HeLa, MCF-7 DrG cell lines, tissues, small living organisms. By targeting cancer-specific pathways copper-related physiological changes, significantly advanced fields diagnostics therapeutics. comprehensive analysis emphasizes potential powerful tool elucidating roles health disease, paving way future advances biomedical research.

Language: Английский

Citations

1

Recent Advancement in Organic Fluorescent and Colorimetric Chemosensors for the Detection of Al3+ Ions: A Review (2019-2024) DOI

F. M. Alshareef,

Jari S. Algethami,

Mohsen A. M. Alhamami

et al.

Journal of environmental chemical engineering, Journal Year: 2024, Volume and Issue: 12(5), P. 114110 - 114110

Published: Sept. 11, 2024

Language: Английский

Citations

7

Impacts of Excessive Iron Intake on Infant Growth and Fluorimetric and Colorimetric Detection Methods: A Comprehensive Review DOI
Alaa Shafie, Amal Adnan Ashour, Faris J. Tayeb

et al.

Journal of Fluorescence, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 13, 2025

Language: Английский

Citations

0

Recent Advances in Dual-Channel Colorimetric and Fluorometric Probes for Selective Sn2+ Detection: Bioimaging and Environmental Perspectives DOI
Amal Adnan Ashour,

Abeer Alubaidi,

Alaa Shafie

et al.

Dyes and Pigments, Journal Year: 2025, Volume and Issue: unknown, P. 112800 - 112800

Published: April 1, 2025

Language: Английский

Citations

0

Pyridine-based fluorescent and colorimetric probes: Advances in metal ion detection and cancer cell imaging (2020–2024) DOI
Alaa Shafie, Amal Adnan Ashour

Microchemical Journal, Journal Year: 2025, Volume and Issue: unknown, P. 113716 - 113716

Published: April 1, 2025

Language: Английский

Citations

0

Live‐Cell Imaging of MicroRNA Expression via Photoinduced Electron Transfer Controlled by Catalytic Hairpin Assembly DOI Creative Commons

Hyebin Na,

Bon Il Koo, Jae Chul Park

et al.

Advanced Healthcare Materials, Journal Year: 2024, Volume and Issue: unknown

Published: June 18, 2024

MicroRNAs (miRNAs) serve as emerging biomarkers for a range of diseases, and their quantitative analysis draws increasing attention. Yet, current invasive methods limit continuous tracking within living cells. To overcome this, nonenzymatic DNA-based nanoprobe is developed dynamic, noninvasive miRNA via live-cell imaging. This probe features unique hairpin DNA structure with five guanines that act internal quenchers, suppressing fluorescence from an attached fluorophore photoinduced electron transfer. Target initiates toehold-mediated strand displacement, restoring, amplifying the signal. Additionally, by introducing single mismatch to DNA, nanoprobe's sensitivity significantly enhanced, lowering detection about 60 pM without compromising specificity. optimize intracellular delivery prolonged monitoring, encapsulated multilamellar lipid nanovesicles, fluorescently labeled dual-wavelength ratiometric analysis. The proposed demonstrates significant advance in detection, promising enhanced situ better understanding miRNAs' pathophysiological function.

Language: Английский

Citations

3

Recent Advances in Calixarenes for the Detection of Metal Ions, Bioimaging Applications, and Anticancer Activities: A Comprehensive Review (2020–2024) DOI
Khairia Mohammed Al‐Ahmary, Alaa Shafie, Amal Adnan Ashour

et al.

Critical Reviews in Analytical Chemistry, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 26

Published: Sept. 16, 2024

The emergence of calixarenes as versatile compounds in recent years marks a significant advancement scientific research. In the area analytical chemistry, have garnered attention for their utility selective chemosensors, enabling sensitive and specific detection metal ions through colorimetric fluorimetric methods. Moreover, found applications bioimaging, where they serve effective probes visualizing biological structures processes with high resolution sensitivity. Additionally, studies explored anticancer properties calixarenes, unveiling potential therapeutic agents cancer treatment. This comprehensive review explores advancements emphasizing significance ions. it highlights mechanisms involved chemosensor design, providing insights into underlying principles driving efficacy. Furthermore, application particularly cellular processes, is discussed, showing biomedical research diagnostics. activity derivatives also explored, shedding light on promising role agents. Through an extensive examination literature, this provides valuable multifaceted offers perspectives future directions.

Language: Английский

Citations

1

Chemosensing Applications of Thiophene Derivatives and Anticancer Potential of Their Platinum-Group Metal Complexes: A Review DOI

Kamelah S. Alrashdi

Comments on Inorganic Chemistry, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 44

Published: July 27, 2024

Thiophene, a heterocyclic compound characterized by five-membered ring comprising four carbon atoms and one sulfur atom, has garnered significant attention in recent research due to its versatile applications medicinal chemosensing fields. Thiophene derivatives formed complexes with various transition metals. These exhibit promising anti-inflammatory, anticancer, antibacterial, antifungal other biological properties. Certainly, the complexation phenomenon involving thiophene can be effectively used for recognition of cations. Thiophene-based compounds act as selective ligands, forming stable specific heavy metal ions. This property implications environmental monitoring, industrial safety, public health, presence ions beyond permissible levels lead detrimental effects. paper explored derivatives, investigating their potential determination covering period from 2018 2024. serve ligands fluorescence colorimetric changes detection Additionally, this study also explores anticancer efficacy demonstrated derived thiophene, emphasis on those platinum-group metals (Ir(III), Ru(II), Ru(III), Rh, Os(II), Os(IV), Pd(II), Pt(II)).

Language: Английский

Citations

0

Understanding The Silent Threat: Lead Exposure in Children and its Detection Using Colorimetric and Fluorimetric Methods DOI
Mohammed Alissa, Awaji Y. Safhi, Meshari A. Alsuwat

et al.

Journal of environmental chemical engineering, Journal Year: 2024, Volume and Issue: 12(5), P. 113973 - 113973

Published: Aug. 28, 2024

Language: Английский

Citations

0