Gamma Radiation-Induced Synthesis and Characterization of Decahedron-Like Silver Nanostructure and Their Antimicrobial Application DOI Creative Commons
Mohamad Bekhit, Gharieb S. El‐Sayyad,

Rehab Sokary

et al.

Journal of Inorganic and Organometallic Polymers and Materials, Journal Year: 2023, Volume and Issue: 33(9), P. 2906 - 2923

Published: June 5, 2023

Abstract In the current study, a decahedron-like silver nanostructure (D-AgNs) was successfully created in an aqueous solution presence of Polyvinylpyrrolidone (PVP) as capping agent using gamma-radiolysis approach without use reducing agent. The synthesized D-AgNs were characterized various analytical tools such UV–Vis. spectroscopy, SEM, XRD, HRTEM, EDX and FTIR. absorption spectra showed considerable surface Plasmon resonance (SPR) bands at 350–600 nm, indicating that colloidal had been synthesized. HRTEM image demonstrates well-dispersed uniformly decahedral shapes are well separated from each other. produced nanoparticles effectively stabilized by PVP through interactions, confirmed FTIR anlaysis. synthesis gamma radiation accomplished, addition its antimicrobial potential, antibiofilm activity, effect UV rays assessed. addition, protein leakage assays SEM imaging employed to analyze reaction’s mechanism. A wide variety bacteria, including S. aureus , P. aeruginosa C. albicans deactivated D-AgNs. assay, inhibited biofilm formation (89.58%), E. coli (80.35%), aureginosa (78.45%). After investigating on growth curve aureus, we concluded affect reduced be 0.125. holes cell membrane is explained fact amount cellular released bacteria directly proportional concentration D-AgNs, which determined 259.25 µg/ml equal 1.0 mg/mL.

Language: Английский

Synthesis and characterization of innovative GA@Ag-CuO nanocomposite with potent antimicrobial and anticancer properties DOI Creative Commons
Amr H. Hashem, Mostafa A. Abdel-Maksoud, Sabiha Fatima

et al.

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: Jan. 3, 2025

Cancer and microbial infections place a significant burden on the world's health systems can increase rate of disease mortality. In current study, novel nanocomposite based Gum Arabic, silver copper oxide nanoparticles (GA@Ag-CuO nanocomposite) was synthesized to overcome problem infection in cancer treatment. Characterization using UV-Vis. spectrophotometer reveals that, observed peak spectrum formed by O.D. at 0.755, confirmed that produced GA@Ag-CuO small discernible 360 nm. The particles' diameters varied from 9.5 nm 49.5 nm, with mean diameter 25.53 ± 1.4 created Arabic filtrate rich active functional groups, provided polydisperse NPs were intended reduce, stabilize, act as capping agents. Based XRD data, crystallized had face-centered (fcc) crystal structure. Biosafety assessed toward Wi 38 normal cell line, where it showed safety tested line IC50 154.2 µg/mL. Antimicrobial results has antibacterial activity MICs 15.6, 125, 31.25 125 µg/mL against S. epidermis, aureus, L. plantrum, typhimurium, respectively. Likewise, antifungal C. albicans neoformans 62.5 15.62 µg/ml, Moreover, displayed promising anticancer 26.11 59.5 µg/ml MCF-7 Hep-G2, conclusion, demonstrated antibacterial, antifungal, activities.

Language: Английский

Citations

2
An eco-friendly and cost-effective approach for the synthesis of a novel GA@CuO–ZnO nanocomposite: characterization, antimicrobial and anticancer activities DOI Creative Commons
Gharieb S. El‐Sayyad, El‐Sayed R. El‐Sayed, Samar H. Rizk

et al.

RSC Advances, Journal Year: 2025, Volume and Issue: 15(1), P. 513 - 523

Published: Jan. 1, 2025

In this study, a nanocomposite based on copper oxide–zinc oxide nanoparticles and Gum Arabic (GA@CuO–ZnO nanocomposite) was successfully synthesized using green method for increasing antimicrobial anticancer activities.

Language: Английский

Citations

2
Optimized silver nanostructures for enhanced antibacterial potential: Recent trends and challenges in the development of metallo-antimicrobials DOI
Shujat Ali, Ali Bahadur, Ali Hassan

et al.

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 160470 - 160470

Published: Feb. 1, 2025

Language: Английский

Citations

2
Gum Arabic assisted the biomass synthesis of bimetallic silver copper oxide nanoparticles using gamma-rays for improving bacterial and viral wound healing: Promising antimicrobial activity against foot and mouth disease DOI
Ahmed I. El‐Batal, M. Eisa,

Mohamed A.M. Saad

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 262, P. 130010 - 130010

Published: Feb. 8, 2024

Language: Английский

Citations

10
Recent design approaches, adhesion mechanisms, and applications of antibacterial surfaces DOI Creative Commons
Paul C. Uzoma, Ini‐Ibehe Nabuk Etim, Bright O. Okonkwo

et al.

Chemical Engineering Journal Advances, Journal Year: 2023, Volume and Issue: 16, P. 100563 - 100563

Published: Sept. 26, 2023

Adhesion of bacteria on surfaces and the resultant biofilm formation is a great risk to human health care services, food packaging storage, marine industry. This has necessitated need for scientific community industries continually develop ways fabricating that can prevent bacterial adhesion, kill adhered bacteria, prevent/disrupt formation. Therefore, this review focused providing an up-to-date discussion recent strategies adopted by researchers in design antibacterial surfaces. It highlighted different surface characterization techniques, discussed mechanism adhesion formation, reviewed method their industrial applications, emphasized advantages drawbacks these proposed outlooks future designs.

Language: Английский

Citations

21
Watermelon Rind Mediated Biosynthesis of Bimetallic Selenium-Silver Nanoparticles: Characterization, Antimicrobial and Anticancer Activities DOI Creative Commons
Amr H. Hashem, Gharieb S. El‐Sayyad, Abdulaziz A. Al–Askar

et al.

Plants, Journal Year: 2023, Volume and Issue: 12(18), P. 3288 - 3288

Published: Sept. 17, 2023

One of the most hazardous diseases that influences human health globally is microbial infection. Therefore, bimetallic nanoparticles have received much attention for controlling infections in current decade. In present study, selenium–silver (Se-Ag NPs) were effectively biosynthesized using watermelon rind WR extract through green technique first time. UV-visible spectroscopy, transmission electron microscopy (TEM), and energy dispersive X-ray spectroscopy (EDX) methods used to characterize produced NPs. The results indicated Se-Ag NPs had synergistic antimicrobial activity at low concentrations, which helped reduce toxicity Ag after preparation increase their great potential. with sizes ranging from 18.3 nm 49.6 detected by TEM. NP surfaces uniformly visible SEM picture. cytotoxicity was assessed against Wi38 normal cell line check safety, where IC50 168.42 µg/mL. showed antibacterial action Candida albicans, Escherichia coli, Pseudomonas aeruginosa, Klebsiella oxytoca, Bacillus subtilis, Staphylococcus aureus a minimum inhibitory concentration (MIC) 12.5 50 Additionally, promising anticancer toward MCF7 cancerous line, 21.6 conclusion, time extract, strong antibacterial, antifungal properties.

Language: Английский

Citations

17
In Vivo and in Vitro activity of colistin-conjugated bimetallic silver-copper oxide nanoparticles against Pandrug-resistant Pseudomonas aeruginosa DOI Creative Commons

Asmaa Abdul Hak,

Hamdallah Zedan, Hadir A. El‐Mahallawy

et al.

BMC Microbiology, Journal Year: 2024, Volume and Issue: 24(1)

Published: June 17, 2024

Abstract Background Addressing microbial resistance urgently calls for alternative treatment options. This study investigates the impact of a bimetallic formulation containing colistin, silver, and copper oxide on pandrug-resistant, highly virulent Pseudomonas aeruginosa (P. aeruginosa) isolate from cancer patient at National Cancer Institute, Cairo University, Egypt. Methods Silver nanoparticles (Ag NPs), (CuO silver-copper (Ag-CuO NPs) were synthesized using gamma rays, combined with colistin (Col), characterized by various analytical methods. The antimicrobial activity Col-Ag NPs, Col-CuO Col-Ag-CuO NPs against P. was evaluated agar well diffusion method, their minimum inhibitory concentration (MIC) determined broth microdilution. Virulence factors such as pyocyanin production, swarming motility, biofilm formation assessed before after NPs. in vivo efficacy Galleria mellonella model, antibacterial mechanism examined through membrane leakage assay. Results optimal synthesis Ag occurred ray dose 15.0 kGy, highest optical density (OD) 2.4 375 nm. Similarly, CuO had an OD 1.5 330 Bimetallic Ag-CuO most potent yielding 1.9 425 MIC significantly reduced when nanoparticles: 8 µg/mL alone, 0.046 0.0117 four-fold compared to Increasing sub-inhibitory 0.29 × 10 -2 0.58 32–64% twitching motility 34–97%. At these concentrations, production decreased 39–58%, inhibited 33–48%. non-toxic , showing 100% survival day 3, similar saline-treated group. Conclusions conjugated presents promising combating challenging pathogen hospital settings. Further research is needed explore elucidate mechanisms underlying effects colistin-bimetallic persistence dissemination.

Language: Английский

Citations

8
Promising antagonistic effect of bimetallic silver-selenium nanoparticles against Ralstonia solanacearum-causing wilt disease in eggplant (Solanum melongena L.) DOI
Mohamed S. Attia, Salem S. Salem,

Abdelrahman A. Elakraa

et al.

Physiological and Molecular Plant Pathology, Journal Year: 2024, Volume and Issue: 133, P. 102369 - 102369

Published: July 26, 2024

Language: Английский

Citations

8
Green biosynthesis of bimetallic selenium–gold nanoparticles using Pluchea indica leaves and their biological applications DOI Creative Commons
Ahmed Mohamed Aly Khalil, Ebrahim Saied, Alsayed E. Mekky

et al.

Frontiers in Bioengineering and Biotechnology, Journal Year: 2024, Volume and Issue: 11

Published: Jan. 11, 2024

Increasing bacterial resistance and the negative impact of currently used antibacterial agents have produced need for novel anticancer drugs. In this regard, nanotechnology could provide safer more efficient therapeutic agents. The main methods nanoparticle production are chemical physical approaches that often costly environmentally unsafe. current study, Pluchea indica leaf extract was biosynthesis bimetallic selenium–gold nanoparticles (Se-Au BNPs) first time. Phytochemical examinations revealed P. includes 90.25 mg/g dry weight (DW) phenolics, 275.53 DW flavonoids, 26.45 tannins. X-ray diffraction (XRD), transmission electron microscopy (TEM), Fourier-transform infrared (FTIR) spectroscopy, dynamic light scattering (DLS), scanning (SEM), energy-dispersive spectroscopy (EDX) techniques were employed to characterize Se-Au BNPs. Based on UV-vis spectra, absorbance BNPs peaked at 238 374 nm. SEM imaging, emerged as bright particles, both Au Se uniformly distributed throughout extract. XRD analysis average size 45.97 showed properties against Escherichia coli , Pseudomonas aeruginosa Staphylococcus aureus Bacillus subtilis with minimum inhibitory concentrations (MICs) 31.25, 15.62, 3.9 μg/mL, respectively. Surprisingly, a cytotoxicity assay IC 50 value toward Wi 38 normal cell line 116.8 implying all MICs described above be safely. More importantly, shown higher efficacy human breast cancer cells (MCF7), an 13.77 μg/mL. conclusion, paper is data effective utilization in biologically active

Language: Английский

Citations

7
Rational design of MoS2 nanoflowers grafted highly porous functionalized woody pulp-derived biochar for sustainable energy storage devices DOI
Heba A. El-Sabban, Sayed Y. Attia, Hamida Y. Mostafa

et al.

Fuel, Journal Year: 2023, Volume and Issue: 359, P. 130485 - 130485

Published: Dec. 2, 2023

Language: Английский

Citations

14