Cited by Experimental and theoretical exploration of Bactericidal and photo-catalytical activities of hierarchically porous AuNRs@CuO nanocomposite

An eco-friendly and cost-effective approach for the synthesis of a novel GA@CuO–ZnO nanocomposite: characterization, antimicrobial and anticancer activities DOI

Gharieb S. El‐Sayyad, El‐Sayed R. El‐Sayed, Samar H. Rizk

et al.

RSC Advances, Journal Year: 2025, Volume and Issue: 15(1), P. 513 - 523

Published: Jan. 1, 2025

In this study, a nanocomposite based on copper oxide–zinc oxide nanoparticles and Gum Arabic (GA@CuO–ZnO nanocomposite) was successfully synthesized using green method for increasing antimicrobial anticancer activities.

Language: Английский

Citations

In Vivo and in Vitro activity of colistin-conjugated bimetallic silver-copper oxide nanoparticles against Pandrug-resistant Pseudomonas aeruginosa DOI

Asmaa Abdul Hak,

Hamdallah Zedan, Hadir A. El‐Mahallawy

et al.

BMC Microbiology, Journal Year: 2024, Volume and Issue: 24(1)

Published: June 17, 2024

Abstract Background Addressing microbial resistance urgently calls for alternative treatment options. This study investigates the impact of a bimetallic formulation containing colistin, silver, and copper oxide on pandrug-resistant, highly virulent Pseudomonas aeruginosa (P. aeruginosa) isolate from cancer patient at National Cancer Institute, Cairo University, Egypt. Methods Silver nanoparticles (Ag NPs), (CuO silver-copper (Ag-CuO NPs) were synthesized using gamma rays, combined with colistin (Col), characterized by various analytical methods. The antimicrobial activity Col-Ag NPs, Col-CuO Col-Ag-CuO NPs against P. was evaluated agar well diffusion method, their minimum inhibitory concentration (MIC) determined broth microdilution. Virulence factors such as pyocyanin production, swarming motility, biofilm formation assessed before after NPs. in vivo efficacy Galleria mellonella model, antibacterial mechanism examined through membrane leakage assay. Results optimal synthesis Ag occurred ray dose 15.0 kGy, highest optical density (OD) 2.4 375 nm. Similarly, CuO had an OD 1.5 330 Bimetallic Ag-CuO most potent yielding 1.9 425 MIC significantly reduced when nanoparticles: 8 µg/mL alone, 0.046 0.0117 four-fold compared to Increasing sub-inhibitory 0.29 × 10 -2 0.58 32–64% twitching motility 34–97%. At these concentrations, production decreased 39–58%, inhibited 33–48%. non-toxic , showing 100% survival day 3, similar saline-treated group. Conclusions conjugated presents promising combating challenging pathogen hospital settings. Further research is needed explore elucidate mechanisms underlying effects colistin-bimetallic persistence dissemination.

Language: Английский

Citations

Enhancing tomato plant immune responses to Fusarium wilt disease by red seaweed Jania sp. DOI

Amer M. Abdelaziz, Ahmed A. El-Refaey, Mohamed H. Sharaf

et al.

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: Aug. 5, 2024

The novelty of this study lies in demonstrating a new approach to control wilt diseases using Jania ethyl acetate extract. In the current investigation, potential impacts sp. extract (JE) on Tomato Fusarium oxysporum (FOW) have been studied. vitro antifungal JE against F. (FO) was examined. GC-MS investigation revealed that, compounds possessing fungicidal action were Phenol,2-methoxy-4-(2-propenyl)-,acetate, Eugenol, Caryophyllene oxide, Isoespintanol, Cadinene, Caryophylla-4(12),8(13)-dien-5à-ol and Copaen. exhibited strong FO, achieving 20 mmzone inhibition. experiment, two different methods applied: soil irrigation (SI) foliar application (FS) JE. results showed that both treatments reduced disease index present DIP by 20.83% 33.33% respectively. findings indicated during FOW, proline, phenolics, antioxidant enzymes activity increased, while growth photosynthetic pigments decreased. morphological features, pigments, total phenol content, enzyme infected plants improved when applied through or methods. It is interesting note had substantially less negative effect isozymes peroxidase polyphenol oxidase tomato plants, compared FOW. These reactions differed depending whether foliarly via soil. Finally, use could be utilized commercially as an ecologically acceptable method protect

Language: Английский

Citations

Synthesis and characterization of innovative GA@Ag-CuO nanocomposite with potent antimicrobial and anticancer properties DOI

Amr H. Hashem, Mostafa A. Abdel-Maksoud, Sabiha Fatima

et al.

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: Jan. 3, 2025

Cancer and microbial infections place a significant burden on the world's health systems can increase rate of disease mortality. In current study, novel nanocomposite based Gum Arabic, silver copper oxide nanoparticles (GA@Ag-CuO nanocomposite) was synthesized to overcome problem infection in cancer treatment. Characterization using UV-Vis. spectrophotometer reveals that, observed peak spectrum formed by O.D. at 0.755, confirmed that produced GA@Ag-CuO small discernible 360 nm. The particles' diameters varied from 9.5 nm 49.5 nm, with mean diameter 25.53 ± 1.4 created Arabic filtrate rich active functional groups, provided polydisperse NPs were intended reduce, stabilize, act as capping agents. Based XRD data, crystallized had face-centered (fcc) crystal structure. Biosafety assessed toward Wi 38 normal cell line, where it showed safety tested line IC50 154.2 µg/mL. Antimicrobial results has antibacterial activity MICs 15.6, 125, 31.25 125 µg/mL against S. epidermis, aureus, L. plantrum, typhimurium, respectively. Likewise, antifungal C. albicans neoformans 62.5 15.62 µg/ml, Moreover, displayed promising anticancer 26.11 59.5 µg/ml MCF-7 Hep-G2, conclusion, demonstrated antibacterial, antifungal, activities.

Language: Английский

Citations

Recent development of copper, silver and their bimetallic nanoparticles: Next-generation antibacterial agents through photocatalysis activity DOI

Jing Chang Chia,

Chin Wei Lai,

Joon Ching Juan

et al.

Journal of Water Process Engineering, Journal Year: 2025, Volume and Issue: 72, P. 107541 - 107541

Published: March 30, 2025

Language: Английский

Citations

Bioinspired Sustainable Development of Ag-CuO/MWCNT Nanocomposites for Antibacterial Applications DOI

Minakshi Y. Deshmukh,

Rohit S. Madankar,

Ratiram Gomaji Chaudhary

et al.

Microbial Pathogenesis, Journal Year: 2025, Volume and Issue: unknown, P. 107516 - 107516

Published: March 1, 2025

Language: Английский

Citations

Synthesis of Bimetallic Copper oxide-silver Nanoparticles by Gum Arabic: Unveiling Antimicrobial, and Antibiofilm Potential against some Pathogenic Microbes Causing Wound Infection DOI

Roqayah Saleh Al-Habeeb,

Widad M. Al-Bishri

Journal of Cluster Science, Journal Year: 2024, Volume and Issue: 35(7), P. 2311 - 2327

Published: July 16, 2024

Language: Английский

Citations

Promising antifungal behavior of biosynthesized bimetallic sliver copper oxide nanoparticles and Bacillus safensis against some strawberry rots DOI

Ahmed I. El‐Batal,

Nerhan A. Eid,

Roqayah Saleh Al-Habeeb

et al.

Physiological and Molecular Plant Pathology, Journal Year: 2024, Volume and Issue: 133, P. 102366 - 102366

Published: July 20, 2024

Language: Английский

Citations

The need for smart bimetallic nanoparticles in the battle against pathogenic multi-drug resistant bacteria: a brief communication DOI

Gharieb S. El‐Sayyad

Discover Bacteria., Journal Year: 2024, Volume and Issue: 1(1)

Published: Aug. 13, 2024

Abstract The expanding threat presented by developing pathogenic multidrug-resistant (MDR) bacteria calls for an urgent need research, particularly given the growing concern global public health. Bimetallic nanoparticles (NPs) have potential to be utilized a broad variety of pharmacological and biological applications because their outstanding antibacterial activity at low concentrations continuous phase stability. This is especially true when it comes preventing MDR from invading. Several synthetic methods producing bimetallic NPs range analytical (used characterize them) are covered in this brief communication paper. Additionally, I tried highlight literature review on antimicrobial capabilities several synthesized NPs. final section discussed structure mechanism action against bacteria. Electrostatic interaction, damage cell membranes, change enzymes proteins, oxidative stress production reactive oxygen species (ROS), binding proteins that disturbs electron transport chain homeostasis, signal transduction suppression, genotoxicity some possible associations with phenomenon being studied.

Language: Английский

Citations

Experimental and theoretical exploration of Bactericidal and photo-catalytical activities of hierarchically porous AuNRs@CuO nanocomposite DOI

Anjali Vijeata,

Alastair W. Wark, Ganga Ram Chaudhary

et al.

Journal of Cleaner Production, Journal Year: 2024, Volume and Issue: unknown, P. 143740 - 143740

Published: Sept. 1, 2024

Language: Английский

Citations