Exploring the relationships between exposure levels of bisphenols and phthalates and prostate cancer occurrence

Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 474, P. 134736 - 134736

Published: May 25, 2024

Language: Английский

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The Ovary as a Target Organ for New Generation Bisphenols Toxicity

Toxics, Journal Year: 2025, Volume and Issue: 13(3), P. 164 - 164

Published: Feb. 26, 2025

Bisphenols (BPs) are a group of organic compounds used extensively in plastics, coatings, and epoxy resins; they have been concern recently due to their endocrine-disrupting effects. Among these, bisphenol A (BPA) is the most studied. Regulatory measures, such as ban on BPA use baby bottles by European Union its restricted thermal paper, reflect growing awareness health risks BPA. To mitigate these risks, analogs S (BPS), F (BPF), others (BPAF, BPAP, BPB, BPP, BPZ) developed alternatives. Despite intended safety, detected environmental media, including indoor dust receipt well human biological samples. Studies report presence urine at levels comparable BPA, with BPS BPF found 78% 55% samples, respectively. In addition, BPs follicular fluid (FF) concentrations that could exert some paracrine effects ovarian function reproductive health. With increased global production BPs, occupational exposure contamination also increase. This review summarizes what currently known about ovary mechanisms which PBs toxicity, particular focus oogenesis, folliculogenesis, steroidogenesis. Further, this emphasizes influence functions need for further biosafety evaluations.

Language: Английский

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Highly Sensitive and High-Throughput Method for the Analysis of Bisphenol Analogues and Their Halogenated Derivatives in Breast Milk

Journal of Agricultural and Food Chemistry, Journal Year: 2017, Volume and Issue: 65(48), P. 10452 - 10463

Published: Nov. 13, 2017

The structural analogs of bisphenol A (BPA) and their halogenated derivatives (together termed BPs) have been found in the environment, food, even human body. Limited research showed that some them exhibited toxicities were similar to or greater than BPA. Therefore, adverse health effects for BPs expected humans with low-dose exposure early life. Breast milk is an excellent matrix could reflect fetuses' babies' contaminants. Some emerging may present trace ultratrace levels humans. However, existing analytical methods breast cannot quantify these simultaneously high sensitivity using a small sampling weight, which important biomonitoring studies. In this paper, method based on Bond Elut Enhanced Matrix Removal-Lipid purification, pyridine-3-sulfonyl chloride derivatization, liquid chromatography electrospray tandem mass spectrometry was developed. requires only quantity sample (200 μL) allowed simultaneous determination 24 ultrahigh sensitivity. limits quantitation proposed 0.001-0.200 μg L-1, 1-6.7 times lower study analysis 3 g weight. mean recoveries ranged from 86.11% 119.05% relative standard deviation (RSD) ≤ 19.5% (n = 6). within 20% RSD < 10% six different lots samples. successfully applied 20 BPA, F (BPF), S (BPS), AF (BPAF) detected. BPA still dominant BP, followed by BPF. This first report describing occurrence BPF BPAF milk.

Language: Английский

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Rapid ultrasound assisted emulsification micro-solid phase extraction based on molecularly imprinted polymer for HPLC-DAD determination of bisphenol A in aqueous matrices

Talanta, Journal Year: 2017, Volume and Issue: 171, P. 242 - 249

Published: May 4, 2017

Language: Английский

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Magnetic nitrogen-doped reduced graphene oxide as a novel magnetic solid-phase extraction adsorbent for the separation of bisphenol endocrine disruptors in carbonated beverages

Talanta, Journal Year: 2019, Volume and Issue: 201, P. 194 - 203

Published: April 5, 2019

Language: Английский

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