Self-powered dual-mode sensing strategy based on graphdiyne and DNA nanoring for sensitive detection of tumor biomarker

Biosensors and Bioelectronics, Journal Year: 2023, Volume and Issue: 237, P. 115557 - 115557

Published: July 29, 2023

Language: Английский

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Recent advances in metal-organic framework-based nanozymes and their enabled optical biosensors for food safety analysis

TrAC Trends in Analytical Chemistry, Journal Year: 2024, Volume and Issue: 173, P. 117602 - 117602

Published: Feb. 23, 2024

Language: Английский

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Self-Powered Biosensor for a Highly Efficient and Ultrasensitive Dual-Biomarker Assay

Analytical Chemistry, Journal Year: 2023, Volume and Issue: 95(14), P. 6046 - 6052

Published: March 28, 2023

A dual-biomarker, self-powered biosensor was fabricated for the ultrasensitive detection of microRNA-21 (miRNA-21) and miRNA-155 based on enzymatic biofuel cells (EBFCs), catalytic hairpin assembly (CHA), DNA hybridization chain reaction (HCR), with a capacitor digital multimeter (DMM). In presence miRNA-21, CHA HCR are triggered lead to generation double-helix chain, which stimulates [Ru(NH3)6]3+ move biocathode surface due electrostatic interaction. Subsequently, obtains electrons from bioanode reduces [Ru(NH3)6]2+, significantly increases open-circuit voltage (E1OCV). When is present, cannot be completed, resulting in low E2OCV. The allows simultaneous miRNA-21 limits 0.15 0.66 fM, respectively. Moreover, this exhibits highly sensitive assay human serum samples.

Language: Английский

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Dual-mode colorimetric-electrochemical biosensor for Vibrio parahaemolyticus detection based on CuO2 nanodot-encapsulated metal-organic framework nanozymes

Sensors and Actuators B Chemical, Journal Year: 2023, Volume and Issue: 387, P. 133835 - 133835

Published: April 14, 2023

Language: Английский

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Novel Self-Powered Biosensor Based on Au Nanoparticles @ Pd Nanorings and Catalytic Hairpin Assembly for Ultrasensitive miRNA-21 Assay

Analytical Chemistry, Journal Year: 2024, Volume and Issue: 96(36), P. 14508 - 14515

Published: Aug. 23, 2024

An ultrasensitive self-powered biosensor is constructed for miRNA-21 detection based on Au nanoparticles @ Pd nanorings (Au NPs@Pd NRs) and catalytic hairpin assembly (CHA). The NRs possess excellent electrical conductivity to improve the electron transfer rate show good elimination of byproduct H2O2 assist glucose oxidase (GOD) catalyze glucose; CHA used as an amplification strategy effectively enhance sensitivity biosensor. To further amplify output signal, a capacitor integrated into With multiple signal strategies, possesses linear range 0.1–10–4 fM lower limit (LOD) 0.032 (S/N = 3). In addition, as-prepared displays potential applicability in assay toward human serum samples.

Language: Английский

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Nitrogen and fluoride co-doped graphdiyne with metal-organic framework (MOF)-derived NiCo2O4–Co3O4 nanocages as sensing layers for ultra-sensitive pesticide detection

Analytica Chimica Acta, Journal Year: 2023, Volume and Issue: 1252, P. 341012 - 341012

Published: March 3, 2023

Language: Английский

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A sandwich-type dual-mode biosensor based on graphdiyne and DNA nanoframework for ultra-sensitive detection of CD142 gene

Biosensors and Bioelectronics, Journal Year: 2023, Volume and Issue: 248, P. 115962 - 115962

Published: Dec. 24, 2023

Language: Английский

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Multipedal DNA Walker: Engineering Strategy, Biosensing Application and Future Perspectives

ACS Sensors, Journal Year: 2024, Volume and Issue: 9(11), P. 5748 - 5762

Published: Oct. 18, 2024

With the continuous development of DNA nanotechnology, walkers have attracted increased attention because their autonomous and progressive walking along predesigned tracks. Compared with traditional walkers, emerged multipedal showed special charm sustainable capability, higher reaction efficiency, expanded region, improved amplification capability. Consequently, developed rapidly shown potential in biosensing applications. Hence, this review, we make a comprehensive representation engineering strategy which focused on design multiple strands as well construction tracks driving forces. Meanwhile, application biosensors has been thoroughly described according to type signal readout. By illustrating some representative works, also summarized merits challenges walker-based offered deep discussion latest progress future.

Language: Английский

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Sensitive detection of cancer biomarker with enzyme-free mediated cascade signal amplification empowered undisturbed dual-mode assay

Sensors and Actuators B Chemical, Journal Year: 2023, Volume and Issue: 394, P. 134430 - 134430

Published: Aug. 9, 2023

Language: Английский

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Universal Detection and Imaging for Multiple Targets by Coupling Target-Primed Nicking-Enhanced Rolling Circle Amplification with Self-Powered DNAzyme Walker

Analytical Chemistry, Journal Year: 2023, Volume and Issue: 95(15), P. 6433 - 6440

Published: April 7, 2023

Although promising in monitoring low-abundance analytes, most of the DNAzyme walker is only responsive to a specific target. Herein, universal, ready-to-use platform developed by coupling nicking-enhanced rolling circle amplification and self-powered (NERSD). It addressed issues that strands need be specifically designed for different biosensing system, allowing highly sensitive analysis various targets with same components. also owing target-dependent ligation padlock probe precise cleavage substrate strand. As typically demonstrated, strategy has an equivalent capacity qRT-PCR kit distinguishing plasma miR-21 levels breast cancer patients from normal subjects able differentiate intracellular ATP confocal imaging. The approach characteristic programmability, flexibility, generality indicated potential all kinds imaging platform.

Language: Английский

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