RSC Advances,
Journal Year:
2024,
Volume and Issue:
14(25), P. 17929 - 17944
Published: Jan. 1, 2024
Representation
of
traditional
detection
methods
and
amplification
strategies
for
the
miRNA,
application
different
types
nanomaterials
in
electrochemical
miRNA
biosensors.
ACS Nano,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 26, 2025
Breast
cancer
has
become
the
most
prevalent
form
of
among
women
on
a
global
scale.
The
early
and
timely
diagnosis
breast
is
utmost
importance
for
improving
survival
rate
patients
with
this
disease.
occurrence
typically
accompanied
by
dysregulation
multiple
microRNA
(miRNA)
expression
profiles.
Consequently,
simultaneous
detection
miRNAs
vital
accurate
cancer.
In
study,
bipolar
self-powered
sensor
was
developed
miRNA-451
miRNA-145
biomarkers
based
specific
catalytic
properties
enzymes.
Selenides
microporous
hollow
cubic
structure
were
designed
prepared,
which
can
markedly
enhance
enzyme
load
activity,
as
well
sensitivity,
due
to
their
extensive
surface
area
three-dimensional
porous
channel.
platform
integrated
into
commercial
chip,
signal
presented
in
smartphone
interface,
thereby
enabling
real-time
continuous
monitoring.
Furthermore,
machine
learning
utilized
predict
miRNA
detection,
encompasses
numerous
stages,
including
data
collection,
feature
extraction,
model
training,
validation.
comparison
limited
sensing
efficiency
biosensors
driven
biofuel
cells,
our
achieved
quantitative
analysis
targets,
providing
robust
tool
more
comprehensive
understanding
function
its
association
cancers.
Journal of Nanobiotechnology,
Journal Year:
2025,
Volume and Issue:
23(1)
Published: March 4, 2025
Graphdiyne
(GDY),
the
sole
synthetic
carbon
allotrope
with
sp-hybridized
atoms,
has
been
extensively
researched
that
benefit
from
its
pore
structure,
fully
conjugated
surfaces,
wide
band
gaps,
and
more
reactive
C≡C
bonds.
In
addition
to
intrinsic
features
of
GDY,
engineering
at
nanoscale,
including
metal/transition
metal
ion
modification,
chemical
elemental
doping,
other
biomolecular
modifications,
endowed
GDY
a
broader
functionality.
This
led
involvement
in
biomedical
applications,
enzyme
catalysis,
molecular
assays,
targeted
drug
delivery,
antitumor,
sensors.
These
promising
research
developments
have
made
possible
by
rational
design
critical
characterization
biomaterials.
contrast
areas,
biomaterials
development
techniques
methods
specific
patterns
some
innovations
based
on
integration
materials
science
biology,
which
are
crucial
for
applications
GDY.
The
objective
this
review
is
provide
comprehensive
overview
essential
process.
Additionally,
general
strategy
will
be
proposed,
limited
help
researchers
field
or
nanomedicine.