ChemElectroChem,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Oct. 2, 2024
Abstract
Synthetic
cocaine
analogs
are
designer
drugs
that
recently
emerged
as
non‐controlled
substitutes
for
their
parent
drug.
Among
them,
nitracaine
is
of
particular
concern
its
psychoactive
effect.
In
this
work,
we
present
a
thorough
characterization
the
electrochemical
behavior
nitracaine,
with
final
quantification
performed
by
differential
pulse
voltammetry
(DPV)
in
ethanol/lithium
perchlorate
0.1
M.
The
selectivity
method
and
reproducibility
results
were
assessed.
LOQ
0.3
μg
mL
−1
linear
dynamic
range
up
to
400
obtained.
addition,
recoveries
from
85
%
101
achieved
on
both
simulated
real
samples.
For
analysis
urine,
clean‐up
preconcentration
step
solid
phase
extraction
(SPE)
using
adsorbent
Florisil
have
been
developed
optimized
through
Design
Experiments
(DoE)
strategy,
thus
achieving
an
enrichment
factor
20.
RSC Advances,
Journal Year:
2024,
Volume and Issue:
14(28), P. 20163 - 20181
Published: Jan. 1, 2024
Because
of
the
serious
risks
they
pose
to
environment
and
public
health,
chlorophenols
(CPs),
a
typical
class
most
persistent
organic
pollutants,
have
drawn
increasing
attention.
Monitoring
CPs
effectively
has
become
pressing
difficult
problem.
The
rapidly
need
for
onsite
real-time
CP
detection
led
consideration
electrochemical
sensing
as
workable
solution.
Molecularly
imprinted
polymer
(MIP)-based
emerged
promising
area
environmental
monitoring
in
response
this
analytical
MIPs,
conjunction
with
miniature
transducers,
provide
opportunity
detect
target
analytes
situ.
These
devices
advantages
great
chemical
physical
stability,
cheap
production
costs,
good
selectivity,
quick
times.
Most
studies
suggest
that
these
sensors
use
nanoparticles
improve
their
properties,
especially
sensitivity.
Furthermore,
successfully
used
real
water
samples
without
time-consuming
pretreatment
procedures.
This
article
provides
an
overview
MIP-based
reported
samples.
To
obtain
highest
sensitivity,
special
is
given
fabrication
sensors,
which
includes
various
functional
monomers,
platforms,
materials.
Several
other
parameters
are
also
discussed,
including
linear
concentration
range,
limit
detection,
types
were
examined.
Polymers,
Journal Year:
2024,
Volume and Issue:
16(17), P. 2528 - 2528
Published: Sept. 6, 2024
This
paper
introduces
a
quantitative
method
for
dopamine
determination.
The
is
based
on
molecularly
imprinted
polypyrrole
(e-MIP)-modified
screen-printed
electrode,
with
differential
pulse
voltammetry
(DPV)
as
the
chosen
measurement
technique.
molecules
are
efficiently
entrapped
in
polymeric
film,
creating
recognition
cavities.
A
comparison
bare
and
non-imprinted
polypyrrole-modified
electrodes
clearly
demonstrates
superior
sensitivity,
selectivity,
reproducibility
of
e-MIP-based
one;
indeed,
sensitivity
0.078
µA
µM−1,
detection
limit
(LOD)
0.8
µM,
linear
range
between
45
µM
dynamic
up
to
350
achieved.
was
successfully
tested
fortified
synthetic
human
urine
samples
underline
its
applicability
screening
biomedical
tests.
Polymers,
Journal Year:
2024,
Volume and Issue:
16(19), P. 2699 - 2699
Published: Sept. 24, 2024
Hazards
associated
with
highly
dangerous
pollutants/contaminants
in
water,
air,
and
land
resources,
as
well
food,
are
serious
threats
to
public
health
the
environment.
Thus,
it
is
imperative
detect
or
decontaminate,
risk-control
strategies,
possible
harmful
substances
sensitively
efficiently.
In
this
context,
due
their
capacity
be
specifically
designed
for
various
types
of
hazardous
compounds,
synthesis
use
molecularly
imprinted
polymers
(MIPs)
have
become
widespread.
By
molecular
imprinting,
affinity
sites
complementary
shape,
size,
functionality
can
created
any
template
molecule.
MIPs'
unique
functions
response
external
factors
attracted
researchers
develop
a
broad
range
MIP-based
sensors
increased
sensitivity,
specificity,
selectivity
recognition
element
toward
target
compounds.
Therefore,
paper
comprehensively
reviews
very
recent
progress
MIPs
smart
polymer
applications
sensing
decontamination
compounds
(e.g.,
drugs,
explosives,
biological
chemical
agents)
fields
from
2020
2024,
providing
rapid
tool
investigating
latest
research
status.
Chemosensors,
Journal Year:
2024,
Volume and Issue:
12(6), P. 99 - 99
Published: June 5, 2024
Modification
of
an
electrode
surface
with
a
selective
layer
leads
to
amplification
the
electrochemical
signal.
A
film
derived
from
electrochemically
oxidized
3-(4-trifluoromethyl)-phenyl)-thiophene
deposited
on
graphite
(ThPhCF3/G)
was
used
estimate
affinity
for
synthetic
stimulants
(2-aminoindane,
buphedrone,
naphyrone)
using
combination
square
wave
voltammetry
and
impedance
spectroscopy.
The
modified
characterized
Raman
spectroscopy,
which
confirmed
that
presence
–PhCF3
group
is
important
recognition
stimulants.
determined
values
adsorption
constants
(Kads)
showed
significance
charge–transfer
and/or
hydrogen
bond
interactions
between—PhCF3
groups
in
polymeric
analyte
interest:
buphedrone
(9.79
×
105)
<
naphyrone
(1.57
106)
2-AI
(1.87
106).
Compared
electrodes
nanomaterial,
PThPhCF3/G-electrodes
highest
sensitivity
concentration
range
1–11
μmol
L−1
at
neutral
pH
possibility
detection
0.43–0.56
μg
mL−1
(sr
=
0.05–0.12).
analytical
performance
ThPhCF3/G
promises
good
perspectives
forensic
samples
without
prior
pretreatment.
Talanta,
Journal Year:
2025,
Volume and Issue:
unknown, P. 127710 - 127710
Published: Feb. 1, 2025
Xylazine
is
a
widely
employed
veterinary
anesthetic
that,
in
recent
years,
has
also
been
used
as
recreational
drug,
leading
to
several
fatal
and
non-fatal
intoxications.
We
present
herein
comprehensive
investigation
of
the
electrochemical
behavior
xylazine,
followed
by
quantification
this
target
analyte.
Specifically,
it
found
that
xylazine
oxidizes
irreversibly
on
glassy
carbon
electrode
ethanol/lithium
perchlorate
media,
with
an
EC
mechanism;
number
electrons
involved
process
equal
two.
The
oxidation
pathway
suggested
supported
thorough
investigation,
which
analyte
compared
other
model
compounds.
A
quantitative
method
was
then
proposed,
employing
differential
pulse
voltammetry
(DPV)
for
determination
real
samples.
analytical
figures
merits
were
computed
from
calibration
curves
obtained
analyzing
standard
solutions
medium.
LOQ
0.2
μg
mL-1
dynamic
range
up
150
achieved.
applied
samples
simulating
"street
tablets"
urine
drug
consumers.
selectivity
method,
well
reproducibility
results,
investigated
interferences
between
common
excipients
human
components.
For
samples,
Florisil-based
clean-up
preconcentration
step
solid
phase
extraction
(SPE)
carried
out.
SPE
strategy
optimized
Design
Experiments
(DoE)
approach,
whereby
enrichment
factor
25
obtained.
Recoveries
87
%
108
achieved
all
examined
suggesting
good
potential
its
application
clinical
forensic
chemistry.
