Frontiers of Environmental Science & Engineering, Journal Year: 2024, Volume and Issue: 19(1)
Published: Oct. 15, 2024
Language: Английский
Frontiers in Lab on a Chip Technologies, Journal Year: 2025, Volume and Issue: 4
Published: Jan. 28, 2025
Microfluidic systems, especially those using capillary forces, have recently attracted considerable interest due to their potential facilitate passive fluid management in portable diagnostic devices and point-of-care settings. These systems utilize forces autonomously regulate flow, eliminating the requirement for external power providing a more straightforward economical option compared active microfluidic systems. This review examines fundamental concepts of capillary-driven microfluidics, emphasizing significant progress design pumps valves, as well influence surface tension, wettability, geometrical configurations microchannels on enhancement dynamics. Furthermore, explores other configurations, such porous solid substrates, illustrate healthcare biochemical applications. Moreover, challenges related managing flow rates enhancing reproducibility are addressed, alongside recent innovations designed overcome these challenges. Capillary offer an effective reliable foundation developing miniaturized instruments, which hold across various domains, including biological research environmental monitoring.
Language: Английский
Citations
1
Micromachines, Journal Year: 2024, Volume and Issue: 15(7), P. 932 - 932
Published: July 22, 2024
Microfluidic separators play a pivotal role in the biomedical and chemical industries by enabling precise fluid manipulations. Traditional fabrication of these devices typically requires costly cleanroom facilities, which limits their broader application. This study introduces novel microfluidic device that leverages passive Zweifach–Fung principle to overcome financial barriers. Through Lagrangian computational simulations, we optimized an eleven-channel configuration achieved perfect 100% recall rate for particles following specified normal distribution. Experimental evaluations determined 2 mL/h as optimal total flow (TFR), under showcased exceptional performance enhancements precision micrometer-sized particles, achieving overall accuracy 94% ± 3%. Fabricated using cost-effective, non-cleanroom method, this approach represents significant shift from conventional practices, dramatically reducing production costs while maintaining high operational efficacy. The cost each chip is less than USD 0.90 cents manufacturing process takes only 15 min. development not makes technology more accessible but also sets new standard future advancements field.
Language: Английский
Citations
8
Micromachines, Journal Year: 2024, Volume and Issue: 15(9), P. 1137 - 1137
Published: Sept. 6, 2024
This review explores significant advancements in polymer science and fabrication processes that have enhanced the performance broadened application scope of microfluidic devices. Microfluidics, essential biotechnology, medicine, chemical engineering, relies on precise fluid manipulation micrometer-sized channels. Recent innovations materials, such as flexible, biocompatible, structurally robust polymers, been pivotal developing advanced systems. Techniques like replica molding, microcontact printing, solvent-assisted injection 3D printing are examined, highlighting their advantages recent developments. Additionally, discusses diverse applications polymer-based devices biomedical diagnostics, drug delivery, organ-on-chip models, environmental monitoring, industrial processes. paper also addresses future challenges, including enhancing resistance, achieving multifunctionality, ensuring biocompatibility, scaling up production. By overcoming these potential for widespread adoption impactful use technologies can be realized.
Language: Английский
Citations
5
Research Society and Development, Journal Year: 2025, Volume and Issue: 14(1), P. e1714147902 - e1714147902
Published: Jan. 3, 2025
A impressão 3D de alimentos é uma tecnologia inovadora com potencial para transformar a fabricação alimentos, permitindo criação produtos personalizados e sustentáveis. Este trabalho teve por objetivo fazer revisão literatura sobre aplicação da na produção abordando avanços científicos tecnológicos. Utilizando técnicas como extrusão, jato tinta sinterização seletiva laser, possível produzir partir proteínas, carboidratos lipídios. Esses nutrientes desempenham um papel crucial formulação dos impressos, influenciando propriedades textura, viscosidade estabilidade, impactando diretamente qualidade final produtos. Embora as diversas vantagens, personalização redução desperdícios, ainda há desafios significativos. Entre os principais estão complexidade técnica, o alto custo equipamentos limitada aceitação pública, devido ao desconhecimento benefícios 3D. Somado isso, questões segurança alimentar, padronização processos escalabilidade precisam ser resolvidas que seja amplamente adotada. técnica extrusão tem sido utilizada à sua flexibilidade no manuseio formulações viscoelásticas. No entanto, necessário estudar outras estereolitografia ampliar possibilidades aplicação, especialmente geometrias complexas ou nutricionais específicas. Conclui-se que, apesar das limitações atuais, revolucionar alimentícia, atendam às demandas sensoriais consumidores modernos.
Citations
0
Elsevier eBooks, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 1, 2025
Citations
0
Elsevier eBooks, Journal Year: 2025, Volume and Issue: unknown, P. 3 - 15
Published: Jan. 1, 2025
Language: Английский
Citations
0
Biosensors, Journal Year: 2025, Volume and Issue: 15(4), P. 211 - 211
Published: March 25, 2025
3D-printed microdevices have become increasingly important to the advancement of point-of-care (POC) immunoassays. Despite its great potential, using surfaces on solid support for immunorecognition has been limited due non-ideal adsorption properties many photocurable resins. In this work, we report a simple surface modification protocol that works diverse commercial resins, improving ELISAs performed directly devices. This strategy involves activation via air plasma followed by one-step incubation GLYMO-labeled streptavidin. We successfully immobilized biotinylated anti-activin A antibodies and complete ELISA surfaces. demonstrated achieved an improved performance over passive ELISAs. The present method is also compatible with resins both microwells microchannels. Finally, comparable limit detection microwells. believe simplicity broad compatibility will facilitate development POC
Language: Английский
Citations
0
MRS Communications, Journal Year: 2025, Volume and Issue: unknown
Published: May 2, 2025
Language: Английский
Citations
0
Biosensors, Journal Year: 2025, Volume and Issue: 15(5), P. 309 - 309
Published: May 12, 2025
This review highlights the latest developments in wearable electrochemical glucose sensors, focusing on their transition from invasive to non-invasive and minimally designs. We discuss underlying mechanisms, performance metrics, practical challenges of these technologies, emphasizing potential revolutionize diabetes care. Additionally, we explore motivation behind this review: provide a comprehensive analysis emerging sensing platforms, assess clinical applicability, identify key research gaps that need addressing achieve reliable, long-term monitoring. By evaluating sensors based tears, saliva, sweat, urine, interstitial fluid, work aims guide future innovations toward more accessible, accurate, user-friendly solutions for diabetic patients, ultimately improving quality life disease management outcomes.
Language: Английский
Citations
0
Journal of Drug Delivery Science and Technology, Journal Year: 2025, Volume and Issue: unknown, P. 107045 - 107045
Published: May 1, 2025
Language: Английский
Citations
0