International Journal of Nanomedicine,
Journal Year:
2024,
Volume and Issue:
Volume 19, P. 5637 - 5680
Published: June 1, 2024
Abstract:
Photodynamic
therapy
(PDT)
is
a
non-invasive
that
has
made
significant
progress
in
treating
different
diseases,
including
cancer,
by
utilizing
new
nanotechnology
products
such
as
graphene
and
its
derivatives.
Graphene-based
materials
have
large
surface
area
photothermal
effects
thereby
making
them
suitable
candidates
for
PDT
or
photo-active
drug
carriers.
The
remarkable
photophysical
properties
of
derivates
facilitate
the
efficient
generation
reactive
oxygen
species
(ROS)
upon
light
irradiation,
which
destroys
cancer
cells.
Surface
functionalization
can
also
enhance
their
biocompatibility
anticancer
activity.
paper
delves
into
distinct
roles
played
graphene-based
photosensitizers
(PS)
carriers
while
at
same
time
considers
how
these
could
be
used
to
circumvent
resistance.
This
will
provide
readers
with
an
extensive
discussion
various
pathways
contributing
inefficiency.
Consequently,
this
comprehensive
review
underscores
vital
derivatives
may
play
emerging
strategies
treatment
other
medical
purposes.
With
better
comprehension
current
state
research
existing
challenges,
integration
holds
great
promise
developing
targeted,
effective,
personalized
treatments.
Keywords:
quantum
dots,
oxide,
research,
photosensitizers,
delivery
Nanotechnology Reviews,
Journal Year:
2024,
Volume and Issue:
13(1)
Published: Jan. 1, 2024
Abstract
Terahertz
metasurface
(THz-MS)
biosensor
is
a
hybrid
technology
that
combines
terahertz
time-domain
spectroscopy
and
for
the
detection
of
biomolecules
cells.
Compared
with
traditional
strategies,
it
label-free,
non-invasive,
time-saving,
easy
to
operate.
However,
three
fundamental
issues,
namely,
low
sensitivity,
specificity,
drastic
water
absorption,
hinder
development
THz-MS
biosensors
clinical
application.
Recently,
numerous
studies
have
been
performed
solve
these
problems,
results
show
great
potential
sensitive
nucleotides,
proteins,
Therefore,
important
summarize
in
biomedical
detection.
In
this
review,
we
summarized
mechanism,
manufacturing,
implementation
biosensors.
Then,
strategies
improve
selectivity,
means
reduce
absorption
are
presented.
Sensitivity
can
be
improved
by
suppressing
electromagnetic
radiation
strengthening
interaction
between
target
molecules
meta-atoms.
Antibodies
aptamers
most
effective
improving
specificity.
Microfluidics
hydrogels
two
ways
absorption.
Subsequently,
applications
nucleotide,
cells
summarized.
Finally,
prospects
future
outlined.
International Journal of Nanomedicine,
Journal Year:
2024,
Volume and Issue:
Volume 19, P. 5637 - 5680
Published: June 1, 2024
Abstract:
Photodynamic
therapy
(PDT)
is
a
non-invasive
that
has
made
significant
progress
in
treating
different
diseases,
including
cancer,
by
utilizing
new
nanotechnology
products
such
as
graphene
and
its
derivatives.
Graphene-based
materials
have
large
surface
area
photothermal
effects
thereby
making
them
suitable
candidates
for
PDT
or
photo-active
drug
carriers.
The
remarkable
photophysical
properties
of
derivates
facilitate
the
efficient
generation
reactive
oxygen
species
(ROS)
upon
light
irradiation,
which
destroys
cancer
cells.
Surface
functionalization
can
also
enhance
their
biocompatibility
anticancer
activity.
paper
delves
into
distinct
roles
played
graphene-based
photosensitizers
(PS)
carriers
while
at
same
time
considers
how
these
could
be
used
to
circumvent
resistance.
This
will
provide
readers
with
an
extensive
discussion
various
pathways
contributing
inefficiency.
Consequently,
this
comprehensive
review
underscores
vital
derivatives
may
play
emerging
strategies
treatment
other
medical
purposes.
With
better
comprehension
current
state
research
existing
challenges,
integration
holds
great
promise
developing
targeted,
effective,
personalized
treatments.
Keywords:
quantum
dots,
oxide,
research,
photosensitizers,
delivery
