Glial and blood-brain barrier cell-derived exosomes: Implications in stroke DOI
Khiany Mathias, Richard Simon Machado,

Taise Petronilho

et al.

Microvascular Research, Journal Year: 2025, Volume and Issue: unknown, P. 104812 - 104812

Published: April 1, 2025

Language: Английский

Targeting to miR-130b-5p/TLR4: How sodium danshensu suppresses inflammatory response of microglia in cerebral ischemia-reperfusion injury DOI
Lin Guo, Miao Zeng, Guangming Zhang

et al.

International Immunopharmacology, Journal Year: 2025, Volume and Issue: 153, P. 114497 - 114497

Published: March 22, 2025

Language: Английский

Citations

0
The diagnostic value of a breast cancer diagnosis model based on serum MiRNAs and serum tumor markers DOI Creative Commons
Xiaohui Li, Feng Wang, Faquan Lin

et al.

World Journal of Surgical Oncology, Journal Year: 2025, Volume and Issue: 23(1)

Published: March 29, 2025

Abstract Background Breast cancer (BCa) is the leading cause of cancer-related death among women worldwide. MicroRNAs (miRNAs) are promising tools for diagnosis and prognosis. This study investigated role serum miRNAs tumor markers (TMs) in BCa. Methods Differentially expressed were screened from samples BCa patients healthy individuals via high-throughput sequencing. The expression hsa-miR-1911-3p, hsa-miR-4694-5p, hsa-miR-548ao-5p, hsa-miR-4804-3p 169 116 controls was detected qRT-PCR. Serum tumor-associated antigens by chemiluminescence. Logistic regression subsequently used to develop miRNA panel I, TM II, (miRNA + TM) III models. Receiver operating characteristic (ROC) curve, precision-recall (PR) curve decision analyses (DCA) performed assess accuracy three models diagnosis. Additionally, relationships between clinical characteristics with assessed. Results Four (hsa-miR-1911-3p, hsa-miR-4804-3p) newly associated I based on hsa-miR-548ao-5p showed greater diagnostic effectiveness than II antigen 125 (CA125) 153 (CA153), AUC values 0.816 0.777, respectively. had higher an value 0.870. miR-548ao-5p miR-4804-3p closely related features, such as human epidermal growth factor receptor 2 (HER2), estrogen (ER), progesterone (PR), HER2-enriched subtype, stage III/IV, lymph node-transplanted breast cancer. Conclusion MiR-548ao-5p miR-4804-3 could serve potential biomarkers

Language: Английский

Citations

0
Extracellular Vesicle-Derived miRNAs in Ischemic Stroke: Roles in Neuroprotection, Tissue Regeneration, and Biomarker Potential DOI Creative Commons
Ceren Eyileten, Pamela Czajka, Izabela Domitrz

et al.

Cellular and Molecular Neurobiology, Journal Year: 2025, Volume and Issue: 45(1)

Published: March 31, 2025

Language: Английский

Citations

0
Glial and blood-brain barrier cell-derived exosomes: Implications in stroke DOI
Khiany Mathias, Richard Simon Machado,

Taise Petronilho

et al.

Microvascular Research, Journal Year: 2025, Volume and Issue: unknown, P. 104812 - 104812

Published: April 1, 2025

Language: Английский

Citations

0