Journal of Drug Delivery Science and Technology, Journal Year: 2023, Volume and Issue: 81, P. 104252 - 104252
Published: Feb. 7, 2023
Language: Английский
Advanced Drug Delivery Reviews, Journal Year: 2021, Volume and Issue: 174, P. 53 - 86
Published: Feb. 3, 2021
Language: Английский
Citations
254
Molecular Cancer, Journal Year: 2023, Volume and Issue: 22(1)
Published: Jan. 12, 2023
Skin cancer has emerged as the fifth most commonly reported in world, causing a burden on global health and economy. The enormously rising environmental changes, industrialization, genetic modification have further exacerbated skin statistics. Current treatment modalities such surgery, radiotherapy, conventional chemotherapy, targeted therapy, immunotherapy are facing several issues related to cost, toxicity, bioavailability thereby leading declined anti-skin therapeutic efficacy poor patient compliance. In context of overcoming this limitation, nanotechnological advancements been witnessed so far. Among various nanomaterials, nanoparticles endowed exorbitant advantages by acting both agents drug carriers for remarkable cancer. small size large surface area volume ratio escalate tumor uptake through their leaky vasculature resulting enhanced efficacy. context, present review provides up date information about different types pathology cancer, followed current associated drawbacks. Furthermore, it meticulously discusses role numerous inorganic, polymer, lipid-based therapy with subsequent descriptions patents clinical trials.
Language: Английский
Citations
195
International Journal of Pharmaceutics, Journal Year: 2021, Volume and Issue: 597, P. 120311 - 120311
Published: Feb. 2, 2021
Language: Английский
Citations
165
Journal of Advanced Research, Journal Year: 2021, Volume and Issue: 36, P. 223 - 247
Published: June 16, 2021
Skin cancer has been the leading type of worldwide. Melanoma and non-melanoma skin cancers are now most common types that have reached to epidemic proportion. Based on rapid prevalence cancers, lack efficient drug delivery systems, it is essential surge possible ways prevent or cure disease.Although surgical modalities therapies made great progress in recent years, however, there still an urgent need alleviate its increased burden. Hence, understanding precise pathophysiological signaling mechanisms all other factors such insults will be beneficial for development more therapies.In this review, we explained new understandings about onset described management via polymeric micro/nano carriers-based therapies, highlighting current key bottlenecks future prospective field. In therapeutic drug/gene approaches, system promising strategy. This review discusses how polymers successfully exploited micro/nanosized systems anticancer genes drugs overcoming barriers limitations associated with available conventional therapies. addition delivery, intelligent nanocarriers platforms also established combination including photodynamic photothermal, theranostic applications. portfolio latest approaches could promote blooming growth research their clinical availability.
Language: Английский
Citations
147
Pharmaceutical Research, Journal Year: 2021, Volume and Issue: 38(6), P. 947 - 970
Published: May 25, 2021
Language: Английский
Citations
136
Advanced Functional Materials, Journal Year: 2021, Volume and Issue: 31(44)
Published: July 28, 2021
Abstract Nanoscale materials have unique properties that make them especially useful for biomedical diagnostic applications. Recent developments in nanoengineering resulted increasing use of nanostructures biosensors. Various types 0D, 1D, 2D, and 3D been used to improve biosensor sensitivity, selectivity, limit detection, time result, among other metrics. These integrated into electrochemical, optical, biosensors this purpose. Here, the most recent advances nanostructured are described. This includes a discussion nanoparticles, nanorods, nanofibers, nanopillars, nanowires, nanosheets, indented nanopatterns (nanoholes nanoslits), nanogaps, nanochannels, nanopores, nanofunctionalized surfaces, complex hierarchical structures their advantages applications Clinical these nanobiosensors also highlighted along with future directions diagnostics.
Language: Английский
Citations
134
Nature Reviews Materials, Journal Year: 2023, Volume and Issue: 8(11), P. 710 - 725
Published: Aug. 29, 2023
Language: Английский
Citations
118
Molecular Cancer, Journal Year: 2023, Volume and Issue: 22(1)
Published: Oct. 6, 2023
Abstract Skin cancer is a global threat to the healthcare system and estimated incline tremendously in next 20 years, if not diagnosed at an early stage. Even though it curable stage, novel drug identification, clinical success, resistance another major challenge. To bridge gap bring effective treatment, important understand etiology of skin carcinoma, mechanism cell proliferation, factors affecting growth, resistance. The current article focusses on understanding structural diversity cancers, treatments available till date including phytocompounds, chemotherapy, radiotherapy, photothermal therapy, surgery, combination molecular targets associated with growth metastasis, special emphasis nanotechnology-based approaches for downregulating deleterious disease. A detailed analysis respect types nanoparticles their scope overcoming multidrug as well trials has been discussed. Graphical
Language: Английский
Citations
107
Advanced Drug Delivery Reviews, Journal Year: 2024, Volume and Issue: 209, P. 115304 - 115304
Published: April 9, 2024
Language: Английский
Citations
20
European Polymer Journal, Journal Year: 2020, Volume and Issue: 142, P. 110129 - 110129
Published: Nov. 7, 2020
Language: Английский
Citations
95