Microneedle-based nanodrugs for tumor immunotherapy DOI

Tianye Wang,

Hongyu Liu, Meng Li

et al.

Journal of Controlled Release, Journal Year: 2025, Volume and Issue: 380, P. 539 - 562

Published: Feb. 13, 2025

Language: Английский

Nanocarrier-Integrated Microneedles: Divulging the Potential of Novel Frontiers for Fostering the Management of Skin Ailments DOI

Pooja Khairnar,

Vivek Phatale,

Shalini Shukla

et al.

Molecular Pharmaceutics, Journal Year: 2024, Volume and Issue: 21(5), P. 2118 - 2147

Published: April 25, 2024

The various kinds of nanocarriers (NCs) have been explored for the delivery therapeutics designed management skin manifestations. NCs are considered as one promising approaches attributable to sustained release and enhanced penetration. Despite extensive applications NCs, challenges in their via barrier (majorly stratum corneum) persisted. To overcome all associated with microneedle (MN) technology has emerged a beacon hope. Programmable drug release, being painless, its minimally invasive nature make it an intriguing strategy circumvent multiple systems. integration positive traits MNs boosts therapeutic effectiveness by evading corneum, facilitating through enhancing targeted delivery. This review discusses function skin, importance MNs, types superiority NC-loaded MNs. We highlighted NC-integrated ailments, combinational delivery, active targeting, vivo imaging, theranostics. clinical trials, patent portfolio, marketed products drug/NC-integrated covered. Finally, regulatory hurdles toward benchtop-to-bedside translation, along prospects needed scale up MN technology, deliberated. current is anticipated deliver thoughtful visions researchers, clinicians, formulation scientists successful development MN-technology-based product carefully optimizing variables.

Language: Английский

Citations

5
Microneedle transdermal drug delivery as a candidate for the treatment of gouty arthritis: Material structure, design strategies and prospects DOI
Yi Hong, Haojie Yu, Li Wang

et al.

Acta Biomaterialia, Journal Year: 2024, Volume and Issue: 187, P. 20 - 50

Published: Sept. 3, 2024

Language: Английский

Citations

5
Carbohydrate-based polymer nanocarriers for environmentally friendly applications DOI
Jagoda Chudzińska, Agata Wawrzyńczak, Agnieszka Feliczak‐Guzik

et al.

Advances in Colloid and Interface Science, Journal Year: 2025, Volume and Issue: unknown, P. 103415 - 103415

Published: Jan. 1, 2025

Language: Английский

Citations

0
Silk fibroin microneedles loaded with melatonin for circadian rhythm regulation DOI
Xiaoyue Li,

Yanai Chen,

Huiyan Shao

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: 301, P. 140500 - 140500

Published: Jan. 30, 2025

Language: Английский

Citations

0
Microneedle-based nanodrugs for tumor immunotherapy DOI

Tianye Wang,

Hongyu Liu, Meng Li

et al.

Journal of Controlled Release, Journal Year: 2025, Volume and Issue: 380, P. 539 - 562

Published: Feb. 13, 2025

Language: Английский

Citations

0