Ultra-processed food consumption and metabolic disease risk: an umbrella review of systematic reviews with meta-analyses of observational studies

Frontiers in Nutrition, Journal Year: 2024, Volume and Issue: 11

Published: Jan. 31, 2024

Background and aims There is an ongoing debate on whether to advocate reducing ultra-processed food (UPF) in dietary guidelines control metabolic disease (such as obesity type 2 diabetes mellitus [T2DM]). We aimed summarize the evidence from systematic reviews with meta-analyses between UPF consumption diseases risk, assess credibility, verify robustness of these associations. Methods systematically searched PubMed, Web Science, Embase, Cochrane Library databases their inception July 15, 2023, identify relevant meta-analyses. used random-effects model evaluate summary effect size, along 95% confidence interval prediction interval. also assessed heterogeneity, small-study effects excess significance bias, categorized credibility each association based quantitative umbrella review criteria. Additionally, we conducted subgroup sensitivity analyses associations continents, study design, assessment methods, definition methods UPF, population, units consumption. Results Overall, 6 13 were included. Three (23.08%) classified highly suggestive for meeting criteria that significant at p < 10 −6 , had more than 1,000 cases, presented largest 0.05. Among them, highest quantile was associated increased risk (OR = 1.55, CI: 1.36–1.77) when compared lowest quantile. The T2DM (RR 1.40, 1.23–1.59) quantile, a 10% increase (% g/d) 1.12, 1.10–1.13). Meanwhile, verified by series analyses. Conclusion may be factor several diseases. However, well-designed studies are still needed our findings future.

Language: Английский

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The association between major gastrointestinal cancers and red and processed meat and fish consumption: A systematic review and meta-analysis of the observational studies

PLoS ONE, Journal Year: 2024, Volume and Issue: 19(6), P. e0305994 - e0305994

Published: June 26, 2024

Background The association between red meat, fish, and processed meat consumption the risk of developing gastrointestinal (GI) cancers remains inconclusive despite several investigations. Therefore, we conducted a systematic review meta-analysis observational studies to update existing scientific evidence. Methods We searched PubMed, Web Science, Scopus databases until May 20, 2023. analyzed that examined associations fish GI cancers. assessed between-study heterogeneity using χ 2 τ tests, as well I statistics. explored likelihood publication bias Begg’s Egger’s tests trim-and-fill analysis. reported overall effect sizes odds ratios (ORs) with 95% confidence interval (CI) random-effects model. Results Of 21,004 identified, 95 involving 5,794,219 participants were included in meta-analysis. high levels compared low levels, was found significantly increase esophageal, pancreatic, liver, colon, rectal, colorectal Similarly, increased In contrast, reduced Conclusions This provides updated evidence on five major types

Language: Английский

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Effects of the Mediterranean Diet on metabolic indices and quality of life in cancer patients: A systematic review and meta-analysis of randomized controlled trials

Journal of Functional Foods, Journal Year: 2024, Volume and Issue: 114, P. 106074 - 106074

Published: Feb. 18, 2024

The Mediterranean diet (MD) had a protective effect on cancer prevention. However, there has not been systematic evaluation of the diet's comprehensive effects metabolic indices and quality life in patients. present meta-analysis summarizes for first time MD We conducted randomized controlled trial (RCT) search PubMed, Embase, Cochrane Library, which recruited patients receiving intervention. In this meta-analysis, nine RCTs were included. Two authors independently extracted data checked accuracy results. Compared with control group, reduced body weight (p < 0.00001), fat mass % = 0.02), waist circumference BMI 0.0001) improved scores FICT-G 0.002), Physical well-being Emotional Functional 0.0002), Fatigue 0.00001). also increased serum vitamin C level. Sensitivity analysis revealed that levels blood glucose triglyceride 0.003), total cholesterol 0.009), LDH-C 0.0002) it did affect HDL-C 0.63) A 0.97). brief, our findings indicate higher compliance can reduce patients, improve their life, alleviate fatigue. Furthermore, potentially patients' lipid metabolism enhance body's antioxidant stress capacity. Nevertheless, further high-quality trials larger sample sizes are necessary to obtain more dependable outcomes. INPLASY registration number: 202320006.

Language: Английский

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Creative Writing in Foreign Language Learning: Systemic Literature Review

International Journal of Arabic-English Studies, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 19, 2025

Creative competence as one of the transformative competencies in future education framework 2030 must begin to be realized foreign language learning, including writing skills. This study aims map position creative existing studies. The method used for tracing is NVivo a coding tool. 78 articles found are then selected by inclusion and exclusion categories produce 25 further coding. results read studied with four perspectives, namely that object study, problems achieving competence, solutions offered benefits can obtained overcome emerging learning problems. findings from this SLR indicate which most dominant English. Linguistic context discourse demotivating non-linguistics problems, while mostly focused on strategies. improvement skills, motivation, self-quality learners. research gap mapped above attention languages other than English discourse-based increased.

Language: Английский

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The trend in pancreatic cancer incidence from 2009 to 2019 and the prediction from 2020 to 2030: An analysis of provincial data in China

Public Health, Journal Year: 2025, Volume and Issue: 243, P. 105693 - 105693

Published: April 12, 2025

Language: Английский

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An umbrella review of the association between dietary factors and hepatocellular carcinoma risk

Food & Function, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Several meta-analyses have summarized the associations between dietary factors and risk of hepatocellular carcinoma (HCC).

Language: Английский

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Burden of digestive system malignancies and its impact on life expectancy in China, 2004–2021

eGastroenterology, Journal Year: 2025, Volume and Issue: 3(2), P. e100148 - e100148

Published: May 1, 2025

Language: Английский

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The association between circulating 25-hydroxyvitamin D and pancreatic cancer: a systematic review and meta-analysis of observational studies

European Journal of Nutrition, Journal Year: 2024, Volume and Issue: 63(3), P. 653 - 672

Published: Jan. 3, 2024

Language: Английский

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ABO and Rhesus blood groups and multiple health outcomes: an umbrella review of systematic reviews with meta-analyses of observational studies

BMC Medicine, Journal Year: 2024, Volume and Issue: 22(1)

Published: May 20, 2024

Numerous studies have been conducted to investigate the relationship between ABO and Rhesus (Rh) blood groups various health outcomes. However, a comprehensive evaluation of robustness these associations is still lacking.

Language: Английский

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Investigating the Dietary Links to Pancreatic Cancer: Case-Control Study on Dairy, Meat, and Egg Consumption

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 24, 2024

Data from several research showed that consumption of specific foods and nutrients are linked to the risk pancreatic cancer, but role meats diary groups in carcinogenesis is still controversial. The main objective this study investigate association between dairy products cancer. A case-control was conducted March 2015 August 2018 at four hospitals Jordan, one them an oncology center. Participants were 101 cases with incident histologically confirmed cancer frequency matched 314 controls. required information for gathered via questionnaires based on face-to-face interviews. An Arabic food-frequency questionnaire (FFQ) has been validated used gather data different food items meat groups. Multinomial logistic regression calculate odds ratios (ORs) their corresponding 95% confidence intervals (CIs), considering potential confounders. levels frequencies yogurt, white cheese, processed red meats, chicken observed increased adjusted OR indicated positively associated daily intake yogurt (OR, 2.88 (95% CI, 1.40–5.91, P value trend = 0.001)), cooked lamb 2.50 1.30–4.84, 0.002)) veal 1.72 1.11–3.77, 0.011)). Furthermore, weekly According study's findings, meat, developing

Language: Английский

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