Harmonizing the inner orchestra: the impact of urbanization and evolution of stress, inflammation, diet, and lifestyles in depression DOI
Kuan‐Pin Su

Current Opinion in Psychiatry, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 27, 2024

This review explores the intersection of urbanization, stress, inflammation, diet, lifestyle changes, and digital evolution as key factors influencing depression, emphasizing necessity for integrative evolutionary perspectives in mental health intervention. Epidemiological studies reveal a dramatic increase common disorders, particularly alongside parallel increases suicide, unemployment, divorce rates. Evolutionary suggest that mechanisms once advantageous survival, such stress responses inflammatory processes, may contribute to challenges modern urban environments. Moreover, crisis among generation Z underscores impact evolution, where shift from play-based phone-based childhood contributes significantly rising depression Recent research highlights significant role omega-3 fatty acids, circadian rhythm regulation, mindfulness, anti-inflammatory interventions mitigating depressive symptoms. The interplay between our heritage rapid societal changes has created "symphony" contributing depression. Understanding these mismatches responses, dietary shifts, disruptions, digitalization provides new insights into etiology holistic approach, conceptualized "harmonizing inner orchestra," offers promising avenues prevention treatment strategies address multifaceted nature world.

Language: Английский

Composition of plant-based diets and the incidence and prognosis of inflammatory bowel disease: a multinational retrospective cohort study DOI
Jie Chen, Yuhao Sun, Lintao Dan

et al.

The Lancet Regional Health - Europe, Journal Year: 2025, Volume and Issue: 52, P. 101264 - 101264

Published: March 14, 2025

Language: Английский

Citations

0

A microbial symphony: a literature review of the factors that orchestrate the colonization dynamics of the human colonic microbiome during infancy and implications for future health DOI Open Access
Edward Horwell,

Philip Bearn,

Simon M. Cutting

et al.

Microbiome Research Reports, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 13, 2024

Since the advent of new sequencing and bioinformatic technologies, our understanding human microbiome has expanded rapidly over recent years. Numerous studies have indicated causal links between alterations to a range pathological conditions. Furthermore, large body epidemiological data is starting suggest that exposure, or lack thereof, specific microbial species during first five years life key implications for long-term health outcomes. These include chronic inflammatory metabolic conditions such as diabetes, asthma, bowel disease (IBD), obesity, with effects lasting into adulthood. Human colonisation these highly dynamic process, multiple environmental exposures recently being characterised influence before stabilises resembles an adult at 3-5 This short period time, known window opportunity, appears “prime” immunoregulation later life. Understanding appreciating this aspect physiology therefore crucial clinicians, scientists, public officials. review outlines most evidence pre- post-natal environments order development microbiome, how influences immunoregulatory pathways, their associated It also discusses limitations current knowledge base, describes potential microbiome-mediated interventions measures may therapeutic in future.

Language: Английский

Citations

1

Harmonizing the inner orchestra: the impact of urbanization and evolution of stress, inflammation, diet, and lifestyles in depression DOI
Kuan‐Pin Su

Current Opinion in Psychiatry, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 27, 2024

This review explores the intersection of urbanization, stress, inflammation, diet, lifestyle changes, and digital evolution as key factors influencing depression, emphasizing necessity for integrative evolutionary perspectives in mental health intervention. Epidemiological studies reveal a dramatic increase common disorders, particularly alongside parallel increases suicide, unemployment, divorce rates. Evolutionary suggest that mechanisms once advantageous survival, such stress responses inflammatory processes, may contribute to challenges modern urban environments. Moreover, crisis among generation Z underscores impact evolution, where shift from play-based phone-based childhood contributes significantly rising depression Recent research highlights significant role omega-3 fatty acids, circadian rhythm regulation, mindfulness, anti-inflammatory interventions mitigating depressive symptoms. The interplay between our heritage rapid societal changes has created "symphony" contributing depression. Understanding these mismatches responses, dietary shifts, disruptions, digitalization provides new insights into etiology holistic approach, conceptualized "harmonizing inner orchestra," offers promising avenues prevention treatment strategies address multifaceted nature world.

Language: Английский

Citations

0