Current Opinion in Clinical Nutrition & Metabolic Care,
Journal Year:
2023,
Volume and Issue:
27(1), P. 17 - 23
Published: July 31, 2023
Purpose
of
review
This
study
aims
to
recent
evidence
(2022–2023)
on
the
role
diet
in
promoting
healthy
aging
older
adults.
Recent
findings
Current
and
is
limited
epidemiological
studies.
A
beneficial
for
individual
domains
intrinsic
capacity,
that
is,
cognition,
locomotion,
vitality,
psychological,
and/or
sensory
functions,
with
sex-specific
differences
reported.
Only
a
few
studies
used
multidimensional
concept
capacity
as
an
outcome.
supports
adults
consists
plenty
plant-based
foods,
adequate
protein-rich
fats.
Next
quantity,
improving
quality
variety
within
food
groups
play
optimizing
health.
Data
associations
between
adherence
national
food-based
dietary
guidelines
are
scarce.
Summary
diet,
centered
foods
fats,
potentially
promotes
aging.
Future
may
evaluate
association
patterns
(particularly
guidelines)
consideration
differences.
Clinical
trials
warranted
inform
causal
effects
outcomes
related
capacity.
Nutrients,
Journal Year:
2023,
Volume and Issue:
15(14), P. 3204 - 3204
Published: July 19, 2023
Alzheimer's
disease
(AD)
is
a
growing
concern
for
the
aging
population
worldwide.
With
no
current
cure
or
reliable
treatments
available
AD,
prevention
an
important
and
area
of
research.
A
range
lifestyle
dietary
patterns
have
been
studied
to
identify
most
effective
preventive
changes
against
AD
related
dementia
(ADRD)
pathology.
Of
these,
are
Mediterranean,
DASH,
MIND,
ketogenic,
modified
Mediterranean-ketogenic
diets.
However,
there
discrepancies
in
reported
benefits
among
studies
examining
these
patterns.
We
herein
compile
narrative/literature
review
existing
clinical
evidence
on
association
with
ADRD
symptomology
contemplate
their
preventive/ameliorative
effects
neuropathology
various
milieus.
By
large,
plant-based
found
be
relatively
consistently
positively
correlated
preventing
reducing
odds
ADRD.
These
impacts
stem
not
only
from
direct
impact
specific
components
within
brain
but
also
indirect
through
decreasing
deleterious
risk
factors,
such
as
diabetes,
obesity,
cardiovascular
diseases.
Importantly,
other
psychosocial
factors
influence
intake,
social
connection,
which
may
directly
diet
lifestyle,
thereby
impacting
risk.
To
this
end,
prospective
research
should
include
holistic
approach,
including
considerations.
Advances in Nutrition,
Journal Year:
2024,
Volume and Issue:
15(3), P. 100184 - 100184
Published: Feb. 3, 2024
The
Mediterranean-Dietary
Approaches
to
Stop
Hypertension
Intervention
for
Neurodegenerative
Delay
(MIND)
diet
seems
a
promising
approach
preserve
brain
function
during
aging.
Previous
systematic
reviews
have
demonstrated
benefits
of
the
MIND
cognition
and
dementia,
though
an
update
is
needed.
Additionally,
other
outcomes
relevant
aging
not
been
summarized.
Therefore,
this
review
aims
give
up-to-date
complete
overview
on
human
studies
that
examined
in
relation
adults
aged
≥40
y.
Ovid
Medline,
Web
Science
core
collection,
Scopus
were
searched
up
July
25,
2023.
Study
quality
was
assessed
using
Newcastle-Ottawa
Scale
Cochrane
Risk-of-Bias
tool.
We
included
40
articles,
which
32
unique
cohorts.
Higher
adherence
protective
dementia
7
10
positive
associations
3
4
cohorts
global
6
episodic
memory.
effects
cognitive
decline
are
less
apparent,
with
only
2
longitudinal
demonstrating
1
memory
decline.
For
(domain-specific
cognition,
impairments,
Parkinson's
disease,
volume,
pathology),
results
mixed
or
few
had
performed.
Many
North
American
origin,
raising
question
if
most
favorable
healthy
population-dependent.
In
conclusion,
provides
observational
evidence
between
risk,
but
remains
and/or
limited.
may
be
preferred
populations,
populations
conclusive.
This
registered
at
PROSPERO
as
CRD42022254625.
British Journal Of Nutrition,
Journal Year:
2024,
Volume and Issue:
132(7), P. 898 - 918
Published: Oct. 14, 2024
Abstract
An
anti-inflammatory
diet
is
characterised
by
incorporating
foods
with
potential
properties,
including
fruits,
vegetables,
whole
grains,
nuts,
legumes,
spices,
herbs
and
plant-based
protein.
Concurrently,
pro-inflammatory
red
processed
meat,
refined
carbohydrates
saturated
fats
are
limited.
This
article
explores
the
effects
of
an
on
non-communicable
diseases
(NCD),
concentrating
underlying
mechanisms
that
connect
systemic
chronic
inflammation,
dietary
choices
disease
outcomes.
Chronic
inflammation
a
pivotal
contributor
to
initiation
progression
NCD.
review
provides
overview
intricate
pathways
through
which
influences
pathogenesis
conditions
obesity,
type
II
diabetes
mellitus,
CVD,
autoinflammatory
diseases,
cancer
cognitive
disorders.
Through
comprehensive
synthesis
existing
research,
we
aim
identify
some
bioactive
compounds
present
in
deemed
anti-inflammatory,
explore
their
capacity
modulate
inflammatory
and,
consequently,
prevent
or
manage
The
findings
demonstrated
herein
contribute
understanding
interplay
between
nutrition,
paving
way
for
future
recommendations
research
regarding
preventive
therapeutic
strategies.
Diabetes Metabolic Syndrome and Obesity,
Journal Year:
2023,
Volume and Issue:
Volume 16, P. 3353 - 3371
Published: Oct. 1, 2023
Purpose:
Recent
studies
have
expanded
the
scope
of
research
on
Mediterranean-DASH
Intervention
for
Neurodegenerative
Delay
(MIND)
diet
beyond
its
impact
cognitive
performance.
These
investigations
specifically
explored
potential
to
provide
protection
against
cardiometabolic
diseases
and
associated
risk
factors,
including
obesity
dyslipidemia.
Methods:
We
systematically
summarized
evaluated
all
existing
observational
trial
evidence
MIND
in
relation
their
factors
adults.
PubMed,
Embase,
CINAHL
Cochrane
Library
databases
were
searched
extract
original
humans
published
until
September
2023,
without
date
restrictions.
A
total
491
initially
retrieved,
out
which
23
met
eligibility
criteria
included
final
review.
Duplicated
irrelevant
screened
by
five
independent
reviewers
using
Rayyan
platform.
Quality
assessment
was
ascertained
Newcastle-Ottawa
scale
risk-of-bias
tool
(RoB
2)
randomized
trials.
Results:
Across
different
study
designs,
generally
with
an
improvement
anthropometric
measures
other
outcomes,
such
as
blood
pressure,
glycemic
control,
lipid
profile,
inflammation
stroke.
The
effects
eating
pattern
some
cardiovascular
are
less
conclusive.
Conclusion:
findings
this
systematic
review
support
recommendation
a
strategy
reduce
Further
well-designed
long-term
warranted.
Keywords:
diet,
dietary
patterns,
diseases,
The journal of nutrition health & aging,
Journal Year:
2024,
Volume and Issue:
28(6), P. 100223 - 100223
Published: April 9, 2024
Previous
studies
suggested
protective
associations
of
vegetables
and
fruits
(VF)
intake
with
cognitive
function,
but
evidence
on
specific
types
VF
was
insufficient.
The
current
study
included
4066
participants
from
1997
to
2006
in
the
China
Health
Nutrition
Survey
(CHNS)
6170
2013
2020
Retirement
Study
(HRS).
Dietary
(using
3-day
24-h
dietary
recalls
CHNS
food
frequency
questionnaire
HRS)
function
Telephone
Interview
for
Cognitive
Status-Modified,
TICS-m)
were
measured.
Linear
mixed-effects
models
used
estimate
beta
coefficients
(β)
95%
confidence
intervals
(CI)
evaluate
association
(z-score)
its
decline.
Highest
total
associated
better
slower
Differences
z-score
between
highest
lowest
tertiles
consumption
0.039
(95%
CI:
0.002,
0.076)
0.063
0.026,
0.100)
HRS.
corresponding
differences
annual
decline
0.011
0.021)
0.012
0.003,
0.020)
units
respectively.
Vegetables
showed
independent
In
subgroups,
when
comparing
tertile
intake,
cruciferous
(β
=
0.058,
0.017,
0.100
β
0.067,
0.032,
0.101
green
leafy
0.036,
−0.001,
0.073
0.082,
0.046,
0.117
both
cohorts.
Similarly,
higher
dark-colored
0.019,
0.008,
0.030
red/yellow
0.004,
0.001,
0.007
subsequent
years.
Moreover,
rigorous
sensitivity
analyses
confirmed
stability
results.
Our
findings
support
potential
beneficial
roles
VF,
especially
vegetables,
maintaining
slowing
middle-aged
older
adults.
Neurology,
Journal Year:
2024,
Volume and Issue:
103(8)
Published: Sept. 18, 2024
Diet
may
influence
the
development
of
cognitive
impairment
and
affect
decline,
but
whether
this
relationship
varies
between
Black
American
White
people
is
unclear.
This
study
examined
association
Mediterranean-Dietary
Approaches
to
Stop
Hypertension
Intervention
for
Neurodegenerative
Delay
(MIND)
incident
trajectories
in
a
biracial
prospective
cohort
study.
Journal of Alzheimer s Disease Reports,
Journal Year:
2025,
Volume and Issue:
9
Published: Jan. 1, 2025
Background
In
contrast
to
existing
evidence
focusing
on
high-income
countries,
this
study
offers
novel
insights
into
the
demographic
and
geographical
context
that
have
yet
be
explored
in
literature.
Comparatively,
Pakistan,
cognitive
impairment
is
one
of
neglected
disorders
can
develop
dementia
Alzheimer's
disease.
As
no
treatment
available,
lifestyle
modifications
are
a
valid
intervention
for
health.
Objective
This
aimed
assess
relationship
between
physical
functionality,
adherence
Mediterranean-DASH
diet
Intervention
Neurological
Delay
(MIND),
among
elderly
individuals
Pakistan.
Methods
From
January
June
2023,
cross-sectional
recruited
462
participants
aged
65
above.
We
used
proven
tools
gerontological
research,
such
as
MIND
quiz
Quick
Physical
Activity
Rating
scale
(QPAR),
evaluate
activity
levels.
Cognitive
function
was
assessed
using
Mini-Mental
State
Examination.
Results
Our
analysis
revealed
26.40%
had
mild
impairment,
whereas
48.50%
demonstrated
low
diet.
The
mean
QPAR
score
20.51
±
18.77.
A
significant
association
found
lower
levels
increased
(adjusted
odds
ratio
9.94,
confidence
interval
(CI):
6.07–16.27).
Additionally,
higher
correlated
with
reduced
(odds
0.29,
CI:
0.18–0.46).
Conclusions
These
findings
highlight
critical
role
health
population.
emphasizes
need
targeted
public
interventions
further
longitudinal
research
explore
long-term
effects
these
factors
The Journal of Prevention of Alzheimer s Disease,
Journal Year:
2025,
Volume and Issue:
unknown, P. 100100 - 100100
Published: March 1, 2025
Dietary
factors
play
a
major
role
in
cognitive
aging,
but
few
studies
have
assessed
and
compared
the
associations
between
specific
dietary
patterns
Alzheimer's
disease
(AD)
mortality.
We
included
27,773
U.S.
participants
(mean
age
=
59.8
years,
51.4
%
female)
from
National
Health
Nutrition
Examination
Survey
(NHANES)
1998
2016,
with
follow-up
for
AD
mortality
until
December
2019.
Five
pattern
scores
were
calculated
utilizing
one
(1999-2002)
or
two
repeated
(2003-2016)
24hr
recalls,
including
Healthy
Eating
Index
(HEI-2015),
healthful
plant-based
diet
index
(hPDI),
alternate
Mediterranean
(aMED),
Approach
to
Stop
Hypertension
(DASH),
Mediterranean-DASH
Intervention
Neurodegeneration
Delay
(MIND)
scores.
utilized
Cox
proportional
hazard
models
evaluate
of
these
A
total
260
deaths
occurred
during
median
9.8
years.
Higher
aMED
score
was
associated
lower
risk
(HRT3vs
T1:
0.72,
95
CI,
0.52-1.00,
p-trend
0.041).
In
sub-sample
2,713
NHANES
2011-2014,
432
individuals
had
prevalent
psychometric
mild
impairment
(p-MCI).
aMED,
MIND,
HEI-2015,
hPDI
odds
p-MCI.
The
potential
contributors
higher
intake
levels
vegetables
nuts,
moderate
alcohol
consumption,
level
sweets.
more
favorable
outcomes
among
middle-aged
older
adults,
underscoring
importance
healthy
long-term
benefits
brain
health.
ABSTRACT
Backgrounds
Dementia
can
impose
a
heavy
economic
burden
on
both
society
and
families.
Alzheimer's
disease
(AD),
the
most
prevalent
form
of
dementia,
is
complex
neurodegenerative
characterized
by
abnormal
deposition
extracellular
amyloid
β‐protein
(Aβ)
aggregation
intracellular
Tau
protein
to
neurofibrillary
tangles
(NFTs).
Given
limited
efficacy
pharmacological
treatment,
scientists
have
already
paid
more
attention
non‐pharmacological
strategies,
including
dietary
restriction
(DR).
DR
refers
nutritional
paradigm
aimed
at
promoting
overall
health
modifying
balance
between
energy
consumption
expenditure.
Studies
demonstrated
that
effectively
extends
healthy
lifespan,
delays
aging
process,
achieves
promising
results
in
prevention
treatment
AD
preclinical
studies.
Methods
In
this
review
we
collected
related
studies
viewpoints
searching
PubMed
database
using
keywords.
Most
citations
were
published
2015
2025.
A
few
older
literatures
also
included
due
their
relevance
significance
field.
Results
We
first
provide
concise
overview
current
therapeutic
preventive
strategies
for
AD.
Then,
introduce
several
specific
protocols
favorable
effects
Furthermore,
potential
mechanisms
underlying
benefits
are
discussed.
Finally,
briefly
highlight
role
maintaining
brain
health.
Conclusion
This
may
offer
valuable
insights
into
development
innovative
treatment.