Ultra-Processed Foods: A Narrative Review of the Impact on the Human Gut Microbiome and Variations in Classification Methods

Nutrients, Journal Year: 2024, Volume and Issue: 16(11), P. 1738 - 1738

Published: June 1, 2024

Ultra-processed foods (UPFs) are that industrially processed and often pre-packaged, convenient, energy-dense, nutrient-poor. UPFs widespread in the current Western diet their proposed contribution to non-communicable diseases such as obesity cardiovascular disease is supported by numerous studies. hypothesized affect body multiple ways, including inducing changes gut microbiome. This review summarizes available research on effect of We also usage NOVA food classification system randomized controlled trials observational studies how its implementation effects UPF research. Despite some differences methodology between studies, results associate consumption with a number negative health consequences. There attempts standardize system; however, reaching implementing consensus difficult. Future focusing mechanisms which body, through microbiome metabolome, will be essential refine our understanding human health.

Language: Английский

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Ultra-processed food consumption and risk of cardiovascular events: a systematic review and dose-response meta-analysis

EClinicalMedicine, Journal Year: 2024, Volume and Issue: 69, P. 102484 - 102484

Published: Feb. 16, 2024

Ultra-processed food (UPF) consumption continues to increase worldwide. However, evidences from meta-analyses are limited regarding the effects on cardiovascular events (CVEs).

Language: Английский

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Association between higher consumption of ultra-processed foods and risk of diabetes and its complications: A systematic review & updated meta-analysis

Metabolism, Journal Year: 2025, Volume and Issue: 165, P. 156134 - 156134

Published: Jan. 21, 2025

Language: Английский

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Ultra-processed foods and risk of all-cause mortality: an updated systematic review and dose-response meta-analysis of prospective cohort studies

Systematic Reviews, Journal Year: 2025, Volume and Issue: 14(1)

Published: March 3, 2025

Ultra-processed food (UPF) consumption has been steadily increasing globally, yet the associated risk of all-cause mortality remains unclear. We aimed to assess UPFs via an updated systematic review and dose-response meta-analysis. A comprehensive literature search was conducted in PubMed, Embase, Cochrane Library for studies published until July 2, 2024, addition referred included previous review. Prospective cohort assessing association between NOVA classification-defined UPF were included. Dose-response meta-analysis a random-effect model used combine results with hazard ratio (HR) as effect measure. Overall, 18 1,148,387 participants (173,107 deaths) identified. Compared lowest, highest had 15% increased (HR = 1.15, 95% CI 1.09–1.22; I2 83.0%). Furthermore, 10% higher detected each increment 1.10, 1.04–1.16; 91.0%). analysis showed positive linear (Pdose-response < 0.001). Moreover, subgroups sensitivity analyses indicated consistent findings, while meta-regression suggested sex distributions partially explained heterogeneity, males. Our meta-analysis, incorporating greater number newly using classification largest sample size date, strengthens evidence linking risk. Strategies such dietary guidelines policies limiting worldwide should be encouraged. PROSPERO CRD42023467226.

Language: Английский

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Ultra-processed foods and cardio-kidney-metabolic syndrome: A review of recent evidence

European Journal of Internal Medicine, Journal Year: 2025, Volume and Issue: unknown

Published: March 1, 2025

Language: Английский

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Unraveling the Evolutionary Diet Mismatch and Its Contribution to the Deterioration of Body Composition

Metabolites, Journal Year: 2024, Volume and Issue: 14(7), P. 379 - 379

Published: July 7, 2024

Over the millennia, patterns of food consumption have changed; however, foods were always whole foods. Ultra-processed (UPFs) been a very recent development and become primary source for many people. The purpose this review is to propose hypothesis that, forsaking evolutionary dietary environment, its complex milieu compounds resulting in an extensive metabolome, contributes chronic disease modern humans. This metabolome may contributed success early hominins. based on following assumptions: (1) promote health, (2) essential nutrients cannot explain all benefits foods, (3) UPFs are much lower phytonutrients other compared (4) diets more diverse metabolome. Evidence will be presented support hypothesis. Nutrition matter systems biology, investigating as humans, help elucidate hidden connections between diet health. effect also shape future guidelines, define healthy

Language: Английский

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Consumption of Ultra-Processed Foods and Semen Quality in Healthy Young Men Living in Italy

Nutrients, Journal Year: 2024, Volume and Issue: 16(23), P. 4129 - 4129

Published: Nov. 29, 2024

Background/Objectives: The study aim was to evaluate the association between UPF consumption and semen quality in a sample of healthy young men Italy. Methods: A cross-sectional analysis carried out using data from 126 participants (mean age ± SD 20.0 1.2 years) enrolled FASt randomized controlled trial. Food intake assessed through European Prospective Investigation into Cancer Nutrition (EPIC) FFQ. items were categorized according Nova classification based on their purpose extent processing as follows: (1) unprocessed/minimally processed foods; (2) culinary ingredients; (3) (4) UPFs. weight ratio (%) each group (g/d) total food then calculated. For analyses, sperm volume, concentration, motility morphology measured. associations (quarters of) parameters estimated multivariable-adjusted linear regression models. Results: Participants consuming high UPFs (Q4), compared those bottom category (Q1), had lower concentration (β = −54.16 × 106 cell/mL; 95%CI: −92.91 −15.40; p for trend 0.0020 across fourths) progressive −14.17%; −28.25 −0.09; 0.036). percentage normal cells tendency decrease amongst subjects more with lowest intake. Conclusions: large dietary inversely associated reproductive-age men. These findings suggest that recommendations improving male fertility health should also recommend limiting

Language: Английский

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Degree of Food Processing is Associated with Glycemic Control in African American Adults with Type 2 Diabetes: Findings from the TX STRIDE Clinical Trial

Journal of the Academy of Nutrition and Dietetics, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 1, 2024

Language: Английский

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Kommentar zu: Stark verarbeitete Lebensmittel verringern Überleben bei Typ-2-Diabetes

Aktuelle Ernährungsmedizin, Journal Year: 2024, Volume and Issue: 49(02), P. 68 - 70

Published: April 1, 2024

Es gibt zunehmend Hinweise dafür, dass der Verzehr hochverarbeiteter Lebensmittel die Entstehung von kardiovaskulären Erkrankungen begünstigt. Kardiovaskuläre treten besonders häufig bei Personen mit Typ-2-Diabetes auf. Die Studie Bonaccio et al. sollte zeigen, ob hochverarbeiteten Lebensmitteln Personen, an erkrankt sind, Gesamtmortalität und Mortalität assoziiert ist.

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