The Effect of Anthocyanins on Cognition: A Systematic Review and Meta-analysis of Randomized Clinical Trial Studies in Cognitively Impaired and Healthy Adults

Current Nutrition Reports, Journal Year: 2025, Volume and Issue: 14(1)

Published: Jan. 29, 2025

Abstract Purpose of the Review Clinical trials suggest that dietary anthocyanins may enhance cognitive function. This systematic literature review and meta-analysis aimed to identify effect anthocyanin on cognition mood in adults. Recent Findings Using a random-effects model, Hedge’s g scores were calculated estimate size. Across 30 randomized controlled trials, fourteen ( n = 733 participants) met criteria for following PRISMA guidelines (Registration number: CRD42021279470). Qualitative synthesis showed improvements multiple domains after intake: short-term memory, verbal learning working executive function, visual-spatial psychomotor skills, attention semantic memory. Four 15 studies reported significant improvements, including anti-fatigue reduced anxiety depression scores. However, there no effects memory (Hedges’s -0.183, 95% CI -0.407 0.041, P 0.110), 0.054, -0.215 0.324, 0.69), immediate 0.196, -0.242 0.633, 0.38) delayed -0.188, -0.629 -0.252, 0.402) according meta-analysis. Summary suggests potential benefits intake mood. 14 eligible studies, working, immediate, not significant, likely due study heterogeneity. Recommendations future designs are discussed.

Language: Английский

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Exploring the acute and chronic effects of a multi-strain probiotic supplement on cognitive function and mood in healthy older adults: A randomised controlled trial

American Journal of Clinical Nutrition, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

Ageing, is associated with a decline in cognitive function and vulnerability to depression. Probiotic supplements have shown beneficial effects on cognition mood clinical populations, but the potential benefit for healthy older adults experiencing age-related remains unclear. The primary aim of present work was explore effect chronic (long-term) multi-species probiotic intervention ageing adults. Secondary aims included exploring outcomes gut microbiota community, as well novel investigation into acute supplementation mood. study employed randomised, placebo-controlled, cross-over trial 30 (1 day) (8 weeks) supplement domains memory executive function, alongside measures stress, anxiety, depression, reactivity sad 16s rRNA sequencing stool samples also performed pre- post- assess microbiota. Acute faster reaction times cognitively demanding trials during task [-64.91ms, CI -115.70, -14.15]. Chronic improvement biases such hopelessness [-0.97, -1.72, -0.23], rumination [-1.58, -2.86, -0.29] aggression [-1.57, -2.63, -0.51] that contribute therefore may improve under higher demand [0.43%, -0.53%, 1.38%]. current provides evidence an probiotics which should be replicated future work. Additionally, this replicates previous findings improved following supplementation, indicating reduce risk developing depression population. This registered at https://clinicaltrials.gov/study/NCT04951687.

Language: Английский

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Impact of Fruit Consumption on Gut Microbiota: Benefits, Contaminants, and Implications for Human Health

Trends in Food Science & Technology, Journal Year: 2024, Volume and Issue: 154, P. 104785 - 104785

Published: Nov. 12, 2024

Language: Английский

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Another piece in the complex puzzle of biological responses to (poly)phenols

American Journal of Clinical Nutrition, Journal Year: 2024, Volume and Issue: 119(3), P. 595 - 596

Published: Feb. 6, 2024

Language: Английский

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Evaluation of phenolic content, antimicrobial susceptibility, and cytotoxic effects of Vaccinium corymbosum L. fruit extracts at different ripening stages

Toxicology and Environmental Health Sciences, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 20, 2024

Language: Английский

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