Published: Jan. 1, 2024
Language: Английский
Ophthalmic and Physiological Optics, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 21, 2025
Language: Английский
Citations
0
Photodiagnosis and Photodynamic Therapy, Journal Year: 2025, Volume and Issue: unknown, P. 104511 - 104511
Published: Feb. 1, 2025
The choroid is a vital vascular layer of the eye, essential for maintaining ocular health. Understanding its structural variations, particularly choroidal thickness (CT), crucial early detection diseases, such as age-related macular degeneration (AMD), high myopia (HM), and diabetes mellitus (DM). Recent advancements in deep learning have significantly improved segmentation measurement layers. This study aims to investigate age- gender-related changes CT components through analysis swept-source optical coherence tomography (SS-OCT) images. A total 262 participants (136 females 126 males) were recruited from Peking University International Hospital. Exclusion criteria included pathologies systemic conditions. SS-OCT was utilized CT, Sattler layer-choriocapillaris complex (SLCCT), Haller (HLT) measurements. auto-measurement method, based on algorithms, ensured accuracy. Ethics approval informed consent obtained all participants. Significant thinning SLCCT observed after age 60, with HLT declining 30. Females exhibited marked between ages 40 50, while males began show at 60. research highlights thickness, particular emphasis gender differences. findings suggest that experience earlier thinning, potentially attributable hormonal changes. Additionally, validates efficiency algorithms measuring thereby enhancing reliability clinical practice.
Language: Английский
Citations
0
Computers in Biology and Medicine, Journal Year: 2025, Volume and Issue: 191, P. 110236 - 110236
Published: April 19, 2025
Language: Английский
Citations
0
Ophthalmic and Physiological Optics, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 24, 2025
Abstract Purpose The purpose of this study was to compare the perception and understanding information provided by ChatGPT regarding myopia among optometry students, optometrists undertaking a Master degree practicing optometrists. Methods This cross‐sectional descriptive using structured questionnaire distributed via Wooclap 225 participants (125 21 Masters students 79 optometrists). All evaluated responses generated Version 4.0 five‐point scale: very poor, acceptable, good good. Data were analysed SPSS, applying analysis chi‐squared tests assess significance differences observed between groups. Results Practicing optometrists, with an average age 39.7 ± 11.0 15.2 7.5 years professional experience, rated on complications more positively than highlighting importance clinical experience ( p < 0.001). Alternatively, may indicate difference in awareness, knowledge training, younger potentially being speculative their evaluations. perceptions about prevention groups similar = 0.28). At same time, effectiveness treatments such as contact lenses pharmaceutical agents showed differences, rating these 0.001 0.004, respectively). Conclusions interpretation depending level education. While AI plays important role education, trust extracted students.
Language: Английский
Citations
0
View, Journal Year: 2025, Volume and Issue: unknown
Published: Feb. 13, 2025
Abstract High myopia stands as the primary cause of blindness globally, with cataract emerging one most prevalent complications. However, underlying mechanism high myopic remains unknown. The lens capsule is basement membrane enclosing lens. In this study, we hypothesized tissue‐derived extracellular vesicles (Ti‐EVs) play a vital role in formation cataract. Ti‐EVs were collected from and age‐related patients during surgery, isolated by ExoDisc. Then, performed proximity barcoding assay for single‐EV analysis, which enabled us to identify alteration Ti‐EV subpopulations associated Among detected proteins, our findings revealed predominant immunity cluster within cataracts, characterized significantly higher abundance macrophage‐derived EVs strongly correlated aquaporin 1 (AQP1) cluster, suggesting potential interaction between these two components progression It was also observed that eye morphogenesis may work concert AQP1, potentially driving cataracts through pathway. These not only shed new light on mechanisms cataract, but pave way development novel therapeutic strategies prevent or treat devastating condition.
Language: Английский
Citations
0
International Ophthalmology, Journal Year: 2025, Volume and Issue: 45(1)
Published: May 5, 2025
Language: Английский
Citations
0
International Immunopharmacology, Journal Year: 2025, Volume and Issue: 157, P. 114803 - 114803
Published: May 5, 2025
Language: Английский
Citations
0
The EPMA Journal, Journal Year: 2024, Volume and Issue: 15(4), P. 573 - 585
Published: Nov. 26, 2024
Language: Английский
Citations
2
Asia-Pacific Journal of Ophthalmology, Journal Year: 2024, Volume and Issue: unknown, P. 100125 - 100125
Published: Dec. 1, 2024
Myopia has ever-rising prevalence in the past few decades globally. Its pathogenesis is still not adequately elucidated especially at signal transduction level. For environmental risk factors, there a large body of fragmented knowledge about visual inputs for accommodation, myopiagenesis and emmetropization, with latter two being essentially local processes. The red-green yellow-blue chromatic pathways, together underlying L-M S-(L+M) cone opponency, seem to be common denominator amongst them. In this review, experimental observational evidence are summarized delineate interplay This review may establish pivotal role longitudinal aberration (LCA) mechanistic approach future research myopia control. looks into processes specifically focusing on opponency vision as components. roles contrast onset development intriguing. How input pathways (specifically, blue-yellow opponency) contribute accommodation that trigger emmetropization mechanisms, thereby influencing eye growth patterns explored discussed. brief, manuscript delves physiology processing highlights foundational aspect science account "Go" or "Stop" signaling axial growth. It further proposes metric gauge myopia-inhibiting optical devices such peripheral defocus lenses, its best iteration. Future above-mentioned areas warranted.
Language: Английский
Citations
1
Frontiers in Public Health, Journal Year: 2024, Volume and Issue: 12
Published: Oct. 4, 2024
Near-sightedness, or myopia, is becoming more prevalent worldwide, but its etiopathogenesis not fully understood. This review examines the potential protective role of green spaces in reducing myopia prevalence among children and adolescents, based on recent epidemiological studies from various countries. The consistently used Normalized Difference Vegetation Index (NDVI) to quantify space exposure. analysis reveals a significant inverse relationship between exposure risk developing across multiple studies. For example, 0.1 increase NDVI within buffer zones around schools was associated with 6.3–8.7% reduction prevalence. Higher residential greenness 100-meter homes linked 38% preschool children. effect observed different age groups, preschoolers high school students. Urban planning factors, such as size, connectivity, aggregation spaces, also influenced risk. These findings suggest that increasing access urban environments may be an effective strategy for prevention, important implications public health policies.
Language: Английский
Citations
0