Polymeric Composite of Magnetite Iron Oxide Nanoparticles and Their Application in Biomedicine: A Review

Polymers, Journal Year: 2022, Volume and Issue: 14(4), P. 752 - 752

Published: Feb. 15, 2022

A broad spectrum of nanomaterials has been investigated for multiple purposes in recent years. Some these studied materials are magnetics nanoparticles (MNPs). Iron oxide (IONPs) and superparamagnetic iron (SPIONs) MNPs that have received extensive attention because their physicochemical magnetic properties ease combination with organic or inorganic compounds. Furthermore, the arresting into a cross-linked matrix known as hydrogel attracted significant interest biomedical field. Commonly, act reinforcing material polymer matrix. In present review, several methods, such co-precipitation, polyol, hydrothermal, microemulsion, sol-gel reported to synthesize magnetite controllable physical chemical suit required application. Due potential magnetite-based nanocomposites, specifically hydrogels, processing including blending, situ precipitation, grafting introduced. Moreover, most common characterization techniques employed study gel discussed.

Language: Английский

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Recent progress on wastewater-based epidemiology for COVID-19 surveillance: A systematic review of analytical procedures and epidemiological modeling

The Science of The Total Environment, Journal Year: 2023, Volume and Issue: 878, P. 162953 - 162953

Published: March 21, 2023

Language: Английский

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A Review of Advanced Multifunctional Magnetic Nanostructures for Cancer Diagnosis and Therapy Integrated into an Artificial Intelligence Approach

Pharmaceutics, Journal Year: 2023, Volume and Issue: 15(3), P. 868 - 868

Published: March 7, 2023

The new era of nanomedicine offers significant opportunities for cancer diagnostics and treatment. Magnetic nanoplatforms could be highly effective tools diagnosis treatment in the future. Due to their tunable morphologies superior properties, multifunctional magnetic nanomaterials hybrid nanostructures can designed as specific carriers drugs, imaging agents, theranostics. Multifunctional are promising theranostic agents due ability diagnose combine therapies. This review provides a comprehensive overview development advanced combining optical providing photoresponsive platforms medical applications. Moreover, this discusses various innovative developments using nanostructures, including drug delivery, treatment, tumor-specific ligands that deliver chemotherapeutics or hormonal resonance imaging, tissue engineering. Additionally, artificial intelligence (AI) used optimize material properties based on predicted interactions with cell membranes, vasculature, biological fluid, immune system enhance effectiveness therapeutic agents. Furthermore, an AI approaches assess practical utility Finally, presents current knowledge perspectives systems models.

Language: Английский

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A comprehensive review on current trends in greener and sustainable synthesis of ferrite nanoparticles and their promising applications

Results in Engineering, Journal Year: 2023, Volume and Issue: 21, P. 101702 - 101702

Published: Dec. 24, 2023

Magnetic nanoparticles, particularly nanosized spinel ferrites, have emerged as promising materials in science, engineering, and medicine due to their unique intriguing properties achieved through various synthesis methods. These nanoparticles play crucial roles research, commercial products, biomedical applications. The increasing interest green methods for magnetic nanocomposites is driven by significance diverse fields, including medicine, environmental remediation. Recently, there has been a burgeoning focus on green-synthesized ferrite (MFe2O4, where M = Co, Cu, Mn, Ni, Zn, Mg) nanocomposites, which find applications chemical, biological, reactions. This review highlights the latest research conducted over last four years producing ferrites containing additional elements, focusing plant microorganism-mediated techniques. surface of nanomaterials energy, sensors, water treatment, antimicrobial activity, heavy metal removal, are discussed. facilitates comprehensive understanding incorporating findings advancements. A thorough knowledge synthesis, properties, highlighted maximizing potential nanoferrites fields.

Language: Английский

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Functionalized nanoparticles: Tailoring properties through surface energetics and coordination chemistry for advanced biomedical applications

Nanoscale, Journal Year: 2023, Volume and Issue: 15(13), P. 6075 - 6104

Published: Jan. 1, 2023

Significant advances in nanoparticle-related research have been made the past decade, and amelioration of properties is considered utmost importance for improving nanoparticle bioavailability, specificity, catalytic performance. Nanoparticle can be tuned through in-synthesis post-synthesis functionalization operations, with thermodynamic kinetic parameters playing a crucial role. In spite robust techniques based on surface chemistry, scalable technologies not explored well. The coordination enhancement via organic/inorganic/biomolecules material has attracted much attention morphology modification shape tuning, which are indispensable aspects colloidal phase during biomedical applications. It envisioned that influences anchoring nano interfaces immobilization functional groups biomolecules. this work, various nanostructure methodologies discussed, aiming to exploit their full potential precision engineering Simultaneous discussions emerging characterization strategies functionalized assemblies gain insights into chemistry. An overview current prospects nanoparticles presented, an emphasis controllable attributes such as size, shape, morphology, functionality, features, Debye Casimir interactions.

Language: Английский

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Magnetic Nanoparticles: Synthesis, Characterization, and Their Use in Biomedical Field

Applied Sciences, Journal Year: 2024, Volume and Issue: 14(4), P. 1623 - 1623

Published: Feb. 17, 2024

In recent years, the use of magnetic nanoparticles (MNPs) in biomedical applications has gained more and attention. Their unusual properties make them ideal candidates for advancement diagnosis, therapy, imaging applications. This review addresses MNPs field biomedicine encompassing their synthesis, biofunctionalization, unique physicochemical that such The synthesis involves a range techniques allow control over particle size, shape, surface modifications. most commonly used play crucial role tailoring are summarized this review. Nevertheless, main characterization can be employed after successful procedure also included together with short description As is rapidly evolving, aims to serve as valuable resource, especially young researchers medical professionals, offering basic but very useful insights into advancements future prospects highly interdisciplinary research topic.

Language: Английский

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A critical review on metal-organic frameworks (MOFs) based nanomaterials for biomedical applications: Designing, recent trends, challenges, and prospects

Heliyon, Journal Year: 2024, Volume and Issue: 10(3), P. e25521 - e25521

Published: Feb. 1, 2024

Nanomaterials (NMs) have garnered significant attention in recent decades due to their versatile applications a wide range of fields. Thanks tiny size, enhanced surface modifications, impressive volume-to-surface area ratio, magnetic properties, and customized optical dispersion. NMs experienced an incredible upsurge biomedical including diagnostics, therapeutics, drug delivery. This minireview will focus on notable examples that tackle important issues, demonstrating various aspects such as design, synthesis, morphology, classification, use cutting-edge applications. Furthermore, we classified outlined the distinctive characteristics advanced nanoscale particles hybrid NMs. Meanwhile, emphasize potential metal-organic frameworks (MOFs), highly group These MOFs gained recognition promising candidates for bio-applications, bioimaging, biosensing, antiviral therapy, anticancer nanomedicines, theranostics, immunotherapy, photodynamic photothermal gene Although shown great field, clinical is still limited by issues stability, cytotoxicity, biocompatibility, health concerns. review article provides thorough analysis offering valuable insights researchers investigating explore new development, expansion opportunities. Remarkably, ponder prospects nanocomposites conjunction with current technology.

Language: Английский

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Aptamer-Based Smart Targeting and Spatial Trigger–Response Drug-Delivery Systems for Anticancer Therapy

Biomedicines, Journal Year: 2024, Volume and Issue: 12(1), P. 187 - 187

Published: Jan. 15, 2024

In recent years, the field of drug delivery has witnessed remarkable progress, driven by quest for more effective and precise therapeutic interventions. Among myriad strategies employed, integration aptamers as targeting moieties stimuli-responsive systems emerged a promising avenue, particularly in context anticancer therapy. This review explores cutting-edge advancements targeted drug-delivery systems, focusing on platforms enhanced spatial aptamer-based we delve into versatile applications aptamers, examining their conjugation with gold, silica, carbon materials. The synergistic interplay between these materials is discussed, emphasizing potential achieving delivery. Additionally, explore an emphasis Tumor microenvironment-responsive nanoparticles are elucidated, capacity to exploit dynamic conditions within cancerous tissues controlled release detailed. External strategies, including ultrasound-mediated, photo-responsive, magnetic-guided examined role effects. integrates diverse approaches precision medicine, showcasing revolutionize

Language: Английский

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Metal-Based Nanoparticles for Cardiovascular Diseases

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(2), P. 1001 - 1001

Published: Jan. 13, 2024

Globally, cardiovascular diseases (CVDs) are the leading cause of death and disability. While there many therapeutic alternatives available for management CVDs, majority classic strategies were found to be ineffective at stopping or significantly/additionally slowing progression these diseases, they had unfavorable side effects. Numerous metal-based nanoparticles (NPs) have been created overcome limitations, demonstrating encouraging possibilities in treatment CVDs due advancements nanotechnology. Metallic nanomaterials, including gold, silver, iron, come various shapes, sizes, geometries. NPs generally smaller more specialized physical, chemical, biological properties. Metal-based may forms, such as nanoshells, nanorods, nanospheres, studied most. Massive potential applications metal nanomaterial structures include supporting molecular imaging, serving drug delivery systems, enhancing radiation-based anticancer therapy, supplying photothermal transforming effects thermal being compounds with bactericidal, fungicidal, antiviral qualities that helpful diseases. In this context, present paper aims review relevant oxide creating an up-to-date framework aids researchers developing efficient strategies.

Language: Английский

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Influence of Physicochemical Properties of Iron Oxide Nanoparticles on Their Antibacterial Activity

ACS Omega, Journal Year: 2024, Volume and Issue: 9(31), P. 33303 - 33334

Published: July 25, 2024

The increasing occurrence of infectious diseases caused by antimicrobial resistance organisms urged the necessity to develop more potent, selective, and safe agents. unique magnetic tunable properties iron oxide nanoparticles (IONPs) make them a promising candidate for different theragnostic applications, including Though IONPs act as nonspecific agent, their activities are directly or indirectly linked with synthesis methods, synthesizing precursors, size, shapes, concentration, surface modifications. Alteration these parameters could accelerate decelerate production reactive oxygen species (ROS). An increase in ROS role disrupts bacterial cell walls, membranes, alters major biomolecules (e.g., lipids, proteins, nucleic acids), affects metabolic processes Krebs cycle, fatty acid synthesis, ATP glycolysis, mitophagy). In this review, we will investigate antibacterial activity bare surface-modified influence physiochemical on activity. Additionally, report potential mechanism IONPs' action driving

Language: Английский

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