Graphene oxide and carbon dots as broad-spectrum antimicrobial agents – a minireview

Nanoscale Horizons, Journal Year: 2018, Volume and Issue: 4(1), P. 117 - 137

Published: Sept. 5, 2018

Complex antibacterial mechanisms of graphene oxide and carbon dots.

Language: Английский

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Advanced Functional Nanostructures based on Magnetic Iron Oxide Nanomaterials for Water Remediation: A Review

Water Research, Journal Year: 2020, Volume and Issue: 190, P. 116693 - 116693

Published: Nov. 30, 2020

Language: Английский

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Iron oxide nanoparticles in biological systems: Antibacterial and toxicology perspective

JCIS Open, Journal Year: 2021, Volume and Issue: 4, P. 100027 - 100027

Published: Oct. 20, 2021

There has been an increasing number of studies in magnetic nanoparticles with auspicious applications medicine. Among the oxides nanoparticles, iron oxide emerged as indispensable tool nanotechnology, particularly bio-nanotechnology. This is attributed to its exceptional properties such size, shape, magnetism, and biocompatibility. In this review, were exploited different model organisms ranging from prokaryotes eukaryotes, elucidating their cellular functions relative antibacterial activity, drug delivery, toxicity.

Language: Английский

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Cytotoxicity of Metal‐Based Nanoparticles: From Mechanisms and Methods of Evaluation to Pathological Manifestations

Advanced Science, Journal Year: 2022, Volume and Issue: 9(16)

Published: March 27, 2022

Metal-based nanoparticles (NPs) are particularly important tools in tissue engineering-, drug carrier-, interventional therapy-, and biobased technologies. However, their complex varied migration transformation pathways, as well continuous accumulation closed biological systems, cause various unpredictable toxic effects that threaten human ecosystem health. Considerable experimental theoretical efforts have been made toward understanding these cytotoxic effects, though more research on metal-based NPs integrated with clinical medicine is required. This review summarizes the mechanisms evaluation methods of cytotoxicity provides an in-depth analysis typical generated nervous, immune, reproductive, genetic systems. In addition, challenges opportunities discussed to enhance future investigations safer for practical commercial adoption.

Language: Английский

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Emerging micropollutants in aquatic ecosystems and nanotechnology-based removal alternatives: A review

Chemosphere, Journal Year: 2023, Volume and Issue: 341, P. 139945 - 139945

Published: Aug. 28, 2023

Language: Английский

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Zebrafish as a Model to Evaluate Nanoparticle Toxicity

Nanomaterials, Journal Year: 2018, Volume and Issue: 8(7), P. 561 - 561

Published: July 23, 2018

Nanoparticles are increasingly being developed for in vivo use, from targeted drug delivery to diagnostics, where they have enormous potential, while also used a variety of applications that can result environmental exposure humans. Understanding how specific nanoparticles interact with cells and cell systems is essential gauge their safety respect either clinical or exposure. Zebrafish employed as model evaluate nanoparticle biocompatibility. This review describes this it be assess toxicity at multiple levels, including mortality, teratogenicity, immunotoxicity, genotoxicity, well alterations reproduction, behavior range other physiological readouts. provides an overview studies using the metal, metal oxide carbon-based nanoparticles. It anticipated information will inform research aimed developing biocompatible uses.

Language: Английский

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Toxicological study of metal and metal oxide nanoparticles in zebrafish

Journal of Applied Toxicology, Journal Year: 2019, Volume and Issue: 40(1), P. 37 - 63

Published: Dec. 29, 2019

Abstract Metal and metal oxide nanoparticles have been widely used in catalytic, electronic biomedical fields. It is necessary to investigate their toxicity potential hazards human aquatic ecosystems. Zebrafish ( Danio rerio ), as a promising animal model, has increasingly utilized assess the of nanoparticles. numerous characteristics for evaluation, such short life cycle high fecundity. This review describes advantages using zebrafish assessment Then we focus on toxic effects, particularly acute chronic ones, induced by zebrafish. Target organ toxicities are also mentioned, including immunotoxicity, developmental toxicity, neurotoxicity, reproductive cardiovascular hepatotoxicity. The effects selected nanoparticles, Au, Ag, Cu, TiO 2 , Al O 3 CuO, NiO ZnO, well underlying mechanisms causing these highlighted described detail. Furthermore, introduce general factors that affect nanoparticle‐induced drawbacks model nanotoxicity studies argued. Finally, suggest application joint other pollutants could be hot topics nanotoxicology.

Language: Английский

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Transcriptomics in aquaculture: current status and applications

Reviews in Aquaculture, Journal Year: 2018, Volume and Issue: 11(4), P. 1379 - 1397

Published: Oct. 12, 2018

Abstract Transcriptomics is the analysis of total RNA transcript in a cell, which gives broad idea cellular processes that are active and dormant. Recent advancement next‐generation sequencing technologies like high‐throughput mRNA ( ‐seq) facilitates deciphering functional complexity whole transcriptome an organism. In recent past, profiling has been widely used aquaculture for effective identification expression candidate genes involved growth, reproduction, development, immunity, disease, stress toxicology. On paucity comprehensive genome sequence, transcriptomics enables detection molecular markers such as simple sequence repeats single‐nucleotide polymorphism associated with trait interest. This review summarizes process current state related to diseases reproduction growth nutrition, toxicology stress. Further, this highlights application transcriptomics, including generation genetic resources, differential gene expression, pathways development markers.

Language: Английский

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Synthesis of iron-based magnetic nanocomposites and applications in adsorption processes for water treatment: a review

Environmental Chemistry Letters, Journal Year: 2020, Volume and Issue: 19(2), P. 1229 - 1274

Published: Nov. 17, 2020

Language: Английский

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Use of Superparamagnetic Iron Oxide Nanoparticles (SPIONs) via Multiple Imaging Modalities and Modifications to Reduce Cytotoxicity: An Educational Review

Journal of Nanotheranostics, Journal Year: 2020, Volume and Issue: 1(1), P. 105 - 135

Published: Dec. 9, 2020

The aim of the present educational review on superparamagnetic iron oxide nanoparticles (SPIONs) is to inform and guide young scientists students about potential use challenges associated with SPIONs. discusses basic concepts magnetic resonance imaging (MRI), construct SPIONs, cytotoxic shape sizes site-specific accumulation various methodologies applied reduce cytotoxicity including coatings materials, application SPIONs in targeted delivery chemotherapeutics (Doxorubicin), biotherapeutics (DNA, siRNA), positron emission tomography (PET) applications.

Language: Английский

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