An analysis of exogenous harmful substance exposure as risk factors for COPD and hypertension co-morbidity using PSM DOI Creative Commons

Qingyang Chen,

Haodong Zhou,

Jiarong Tang

et al.

Frontiers in Public Health, Journal Year: 2024, Volume and Issue: 12

Published: June 25, 2024

Background Some occupational and environmental exposures could increase the risk of chronic obstructive pulmonary disease (COPD) hypertension in various work living environments. However, effect exposure to multiple exogenous harmful substances on COPD co-morbidities remains unclear. Methods Participants were selected from eight hospitals five provinces China using a multistage cluster sampling procedure. Participants' demographic, exposure, information collected through questionnaires, spirometry, blood pressure examinations. Demographic data used as matching factors, 1:1 between exposed non-exposed groups was performed by employing propensity score (PSM) minimize influence results. A one-way chi-squared analysis multifactorial logistic regression analyze association (metals their compound dust, inorganic mineral organic chemicals, livestock by-products) co-morbidity hypertension. Results There 6,610 eligible participants final analysis, whom 2,045 (30.9%) substances. The prevalence (6.0%) group higher than total population (4.6%). After PSM, substance found be factor for [odds ratio (OR) = 1.347, 95% confidence interval (CI): 1.011–1.794], which not statistically significant before PSM (OR 1.094, CI: 0.852–1.405). Meanwhile, results different outcomes showed that 0.965, 0.846–1.101). Smoking 4.702, 3.321–6.656), history respiratory during childhood 2.830, 1.600–5.006), symptoms 1.897, 1.331–2.704) also identified factors Conclusion distribution varies population, is generally susceptible populations. Exposure key after adjusting demographic confounders.

Language: Английский

The Impact of COVID-19 on Migraine: The Patients’ Perspective DOI Creative Commons
A de Torrenté, Paolo Alonge, Roberta Baschi

et al.

Life, Journal Year: 2024, Volume and Issue: 14(11), P. 1420 - 1420

Published: Nov. 4, 2024

The COVID-19 pandemic represents a global health phenomenon that will sadly remain part of our history. It had innumerable consequences for society and people’s lives. With different mechanisms, has been pointed out as factor in the pathophysiology several secondary disorders or deterioration pre-existing conditions. Migraine is frequent disorder can be influenced by conditions, including psychologically stressful conditions infectious diseases. purpose present study to gain insight into influence on clinical characteristics patients with migraine. A self-administrable questionnaire developed, asking migraine features before after infection. One hundred two who infected at least once were included. After infection, 54 reported worsening migraine, 45 noticed no variation, 3 an improvement. 21 changed preventive therapy due loss efficacy previous one. most effective treatments this subpopulation gene-related peptide monoclonal antibodies. presented data confirm heterogeneous but new may controlling symptoms among those report disease.

Language: Английский

Citations

2
Current Understanding of Post-COVID Pulmonary Fibrosis: Where Are We? DOI Open Access
Guilherme das Posses Bridi, Suzana Érico Tanni, Bruno Guedes Baldi

et al.

Archivos de Bronconeumología, Journal Year: 2022, Volume and Issue: 59(2), P. 69 - 70

Published: Aug. 13, 2022

Language: Английский

Citations

9
Post-COVID-19 Symptoms in Adults with Asthma—Systematic Review DOI Creative Commons
Marek Kaszuba,

Natalia Madej,

Rafał Piliński

et al.

Biomedicines, Journal Year: 2023, Volume and Issue: 11(8), P. 2268 - 2268

Published: Aug. 14, 2023

Background: Research on the longer-term sequelae of COVID-19 in patients with asthma is limited. Objective: To assess frequency and severity long-term symptoms population patients. Methods: A systematic review published literature was conducted accordance recommendations PRISMA statement. EMBASE, MEDLINE/PubMed, Web Science, CINAHL, Scopus Scholar were searched for terms related to post or long COVID-19, reviews specific questions within our review, up June 2022. Results: Data from 9 references publications included extracted. total 1466 adult asthmatic infection described all mentioned above. Of reported after indicated: lower respiratory symptoms, fatigue, cognitive psychological problems, other such as skin rashes, gastrointestinal disorders, tachycardia, palpitations, ocular ageusia/hypogeusia, anosmia/hyposmia, poor sleep quality. These similar intensity observed comparison groups without a diagnosis asthma. Conclusions: The data neither confirm nor deny that are different strength diagnosis. indicate associations between severity, well more longitudinal research needed chronic phenotypes, treatment, degree control.

Language: Английский

Citations

4
ACE2: the node connecting the lung cancer and COVID-19 DOI Open Access

Liao Yan

American Journal of Cancer Research, Journal Year: 2024, Volume and Issue: 14(4), P. 1466 - 1481

Published: Jan. 1, 2024

Angiotensin-converting Enzyme 2 (ACE2) collaborates with Angiotensin (Ang) 1-7 and Mas receptors to establish the ACE2-Ang (1-7)-Mas receptor axis.ACE2 impacts lung function can cause injury due its inflammatory effects.Additionally, ACE2 contributes pulmonary vasculature dysfunction, resulting in hypertension.In addition, is a for coronavirus entry into host cells, leading infection.Lung cancer, one of most common respiratory diseases worldwide, has high rate infection.Elevated levels cancer patients, which increase risk SARS-CoV-2 infection severe disease, have been demonstrated clinical studies by molecular mechanisms.The association between closely linked ACE2.This review examines basic pathophysiological role lung, longterm effects on function, development fibrosis, chronic inflammation long-term COVID research mechanisms underlying increased susceptibility patients virus.Possible SARS-CoV-2-infected individuals potential this process are also explored review.The as therapeutic target novel summarized.This will help inform prevention treatment complications patients.

Language: Английский

Citations

1
An analysis of exogenous harmful substance exposure as risk factors for COPD and hypertension co-morbidity using PSM DOI Creative Commons

Qingyang Chen,

Haodong Zhou,

Jiarong Tang

et al.

Frontiers in Public Health, Journal Year: 2024, Volume and Issue: 12

Published: June 25, 2024

Background Some occupational and environmental exposures could increase the risk of chronic obstructive pulmonary disease (COPD) hypertension in various work living environments. However, effect exposure to multiple exogenous harmful substances on COPD co-morbidities remains unclear. Methods Participants were selected from eight hospitals five provinces China using a multistage cluster sampling procedure. Participants' demographic, exposure, information collected through questionnaires, spirometry, blood pressure examinations. Demographic data used as matching factors, 1:1 between exposed non-exposed groups was performed by employing propensity score (PSM) minimize influence results. A one-way chi-squared analysis multifactorial logistic regression analyze association (metals their compound dust, inorganic mineral organic chemicals, livestock by-products) co-morbidity hypertension. Results There 6,610 eligible participants final analysis, whom 2,045 (30.9%) substances. The prevalence (6.0%) group higher than total population (4.6%). After PSM, substance found be factor for [odds ratio (OR) = 1.347, 95% confidence interval (CI): 1.011–1.794], which not statistically significant before PSM (OR 1.094, CI: 0.852–1.405). Meanwhile, results different outcomes showed that 0.965, 0.846–1.101). Smoking 4.702, 3.321–6.656), history respiratory during childhood 2.830, 1.600–5.006), symptoms 1.897, 1.331–2.704) also identified factors Conclusion distribution varies population, is generally susceptible populations. Exposure key after adjusting demographic confounders.

Language: Английский

Citations

1