Sex differences in motivation to take sucrose following abstinence and environmental enrichment in Long-Evans rats.

Physiology & Behavior, Journal Year: 2025, Volume and Issue: 291, P. 114810 - 114810

Published: Jan. 10, 2025

Language: Английский

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Environmental enrichment with nylon gnaw sticks introduces variation in Sprague Dawley rat immune and lower gastrointestinal parameters with differences between sexes

Animal Microbiome, Journal Year: 2025, Volume and Issue: 7(1)

Published: Jan. 31, 2025

Environmental enrichment (EE) is commonly included as an important component of animal housing to promote well being laboratory animals; however, much remains be learned about the impact chewable forms EE on experimental outcomes in context nutritional and microbiome-related studies, whether differ between sexes. In present study, nylon chew bones (gnaw sticks, GS) were evaluated for their effects fermentation profiles, microbial community structure, cytokine profiles gastrointestinal systemic tissues pair-housed female male Sprague Dawley (SD) rats. Food consumption weight gain not significantly altered by access GS. Cecal short-chain fatty acid branched-chain differed sexes rats with GS, alpha diversity microbiome decreased females provided Sex-related tissue also without These findings indicate that including GS can influence microbiota immune-related parameters, a sex dependent manner. This shows environmental strategies need clearly reported publications properly evaluate compare results, especially respect use studies examining diet, immune parameters.

Language: Английский

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From memory disorders to the development of depression: a system approach

Biosystems, Journal Year: 2025, Volume and Issue: unknown, P. 105440 - 105440

Published: March 1, 2025

Language: Английский

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Effects of an Enriched Environment on Learning and Memory in the Morris Water Maze in Rats with Acute and Chronic Proinflammatory Stress

Neuroscience and Behavioral Physiology, Journal Year: 2025, Volume and Issue: unknown

Published: April 14, 2025

Language: Английский

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The systemic effects of the enriched environment on the conditioned fear reaction

Frontiers in Behavioral Neuroscience, Journal Year: 2023, Volume and Issue: 17

Published: Aug. 22, 2023

In this review, a hypothesis is proposed to explain the beneficial effect of an enriched environment (EE) on conditioned fear reaction (CFR) from perspective functional system behavioral control. According hypothesis, EE affects all act components, including processing sensory information, memory, motivational and reinforcing systems, motor activities, which weakens CFR. Animals raised in have effects that are comparable those context (CTX) CS pre-exposures at latent inhibition. An abundance stimuli constant contact with them provide formation CS-noUS CTX-noUS connections later, during CFR learning, slow down diminish fear. The also contributes faster information habituation it. As result, many lose their significance, subjects simply ignore them. And finally, brain mechanisms, induces impairment search activity, worsens memory consolidation, leads reduction

Language: Английский

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Interstitial cystitis—an imbalance of risk and protective factors?

Frontiers in Pain Research, Journal Year: 2024, Volume and Issue: 5

Published: May 9, 2024

Interstitial cystitis (IC) presents as a chronic pain condition with variable combinations of symptoms depending on the species and individual patient. It is diagnosed by presence lower urinary tract signs in combination variety comorbid health problems, history life adversities, absence other conditions that could cause signs. IC occurs naturally humans cats dimensional condition, patients presenting mild, moderate, severe symptoms. Most appear to recover without specific treatment. A number rodent models have been used study its causes treatments. Unfortunately, current therapies generally fail ameliorate long-term. The recent classification primary disorder calls for rethinking clinical research approaches it. Beginning when patient encounters clinician, precipitating, perpetuating, palliating risk factors can be addressed until or reliably effective therapy identified, identifying predisposing preventive inform epidemiological studies promotion interventions. Predisposing, perpetuating factors, including environmental, psychological, biological, increase activity central threat response system (CTRS), which plays clinically important role Studies revealed environmental enrichment (EE), bladder-directed therapies, leads amelioration symptoms, implying CTRS symptom precipitation perpetuation. Conceptually moving source brain motivational state rather than one resulting from peripheral nociceptive input offers both clinicians researchers novel opportunities improve care use more ecologically valid models. may even results an excess protective making this imbalance targetable consequence IC.

Language: Английский

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The influence of enriched environment on learning and memory in the Morris water maze in rats with acute and chronic pro-inflammatory stress

Журнал высшей нервной деятельности им И П Павлова, Journal Year: 2024, Volume and Issue: 74(5), P. 621 - 631

Published: Nov. 27, 2024

Language: Английский

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