Obstetrics and Gynecology, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 2, 2025
OBJECTIVE: To investigate whether yoga and meditation added to usual care improves treatment response in women with interstitial cystitis–bladder pain syndrome. METHODS: This randomized trial compared syndrome receiving standard alone (control group) those plus (mind–body group). Standard was defined as behavioral changes or medications recommended by the American Urological Association. Individuals control group received care, mind–body augmented a commercially available application standardized tutorial video. Both groups continued their current treatments. The primary outcome modified GRA (Global Response Assessment), comparing responders (moderately, markedly improved) nonresponders at 12 weeks. On power analysis assuming α=5% β=80%, sample size of 82 participants required find 30% difference on between groups. Weekly scores over weeks were also compared. Secondary outcomes included ICPI (Interstitial Cystitis Problem Index)/ICSI Symptom Index), pain, interference, anxiety/depression, self-efficacy escalation RESULTS: Among 97 (49 group, 48 group), did not differ characteristics symptoms baseline. had more (31/43 [72.1%] vs 10/39 [25.6%], relative risk [RR] 2.8, 95% CI, 1.6–4.6), corroborated superior weekly results beneficial change (RR 1.8, 0.5–3.1), ICSI 1.9, 0.2–3.6), 1.4, 0.4–2.5) than less (2/45 [4.4%] 14/42 [33.3%], RR 0.13, 0.03–0.55). CONCLUSION: addition associated improved fewer additional interventions alone. CLINICAL TRIAL REGISTRATION: ClinicalTrials.gov, NCT04820855.
Language: Английский