Advanced Science,
Journal Year:
2024,
Volume and Issue:
11(40)
Published: Aug. 29, 2024
Abstract
The
demineralization
of
dental
hard
tissue
imposes
considerable
health
and
economic
burdens
worldwide,
but
an
optimal
method
that
can
repair
both
the
chemical
composition
complex
structures
has
not
been
developed.
continuous
development
nanotechnology
created
new
opportunities
for
regeneration
tissue.
Increasingly
studies
have
reported
nanomaterials
(NMs)
induce
regulate
biomimetic
mineralization
tissue,
few
examined
how
they
are
involved
in
different
stages,
let
alone
relevant
mechanisms
action.
Besides
their
nanoscale
dimensions
excellent
designability,
NMs
play
a
corresponding
role
function
raw
materials
mineralization,
mineralized
microenvironment,
guidance,
products.
This
review
comprehensively
summarizes
advantages
examines
specific
mechanisms.
Design
strategies
to
promote
summarized
according
application
purpose
oral
cavity,
limitations
directions
remineralization
proposed.
provide
theoretical
basis
understand
interaction
between
thereby
optimizing
design
strategy,
rational
development,
clinical
field
remineralization.
Journal of the mechanical behavior of biomedical materials/Journal of mechanical behavior of biomedical materials,
Journal Year:
2024,
Volume and Issue:
152, P. 106420 - 106420
Frontiers in Bioengineering and Biotechnology,
Journal Year:
2023,
Volume and Issue:
11
Published: Aug. 1, 2023
The
continuous
destruction
of
dental
hard
tissues
increases
the
risk
bacterial
invasion,
which
leads
to
pulp
infections.
Irrigation
is
critical
for
successful
root
canal
treatment
in
terms
infection
control.
However,
no
single
irrigant
covers
all
functions
demanded,
including
antibiofilm
and
tissue-dissolving
activities.
aim
this
study
was
investigate
antimicrobial
properties
Triton,
an
all-in-one
irrigant,
on
Enterococcus
faecalis
multispecies
oral
biofilms
dentin
canals,
as
well
its
ability
remove
smear
layer.
Dentin
blocks
(192
specimens)
were
prepared
from
single-root
human
teeth
then
assigned
48
groups
(24
each
biofilm
type).
Serial
centrifugation
used
introduction
into
dentinal
tubules.
After
3
weeks,
half
specimens
created
a
uniform
following
treatments
applied:
short
time
(separate):
6%
NaOCl,
2%
water
(all
min);
(combined):
Triton
(3
+
1
min),
NaOCl
+17%
EDTA
or
2
long
time:
(5
min).
Confocal
laser
scanning
microscopy
electron
employed
examine
activity
layer
removal,
respectively.
results
revealed
that
despite
absence
presence
layer,
min)
showed
highest
killing
both
tested
(61.53%-72.22%)
among
(p
<
0.05).
Furthermore,
removed
by
after
min,
exposing
open
canals.
These
findings
demonstrated
can
provide
dual
benefits
removal
capabilities
simultaneously,
indicating
simplified
effective
strategy
application
treatment.
Advanced Healthcare Materials,
Journal Year:
2023,
Volume and Issue:
13(8)
Published: Dec. 2, 2023
Dentin
hypersensitivity
(DH)
is
a
prevalent
dental
condition
arising
from
the
exposure
of
dentin
tubules
(DTs),
leading
to
discomfort
upon
external
stimuli.
However,
achieving
swift
and
profound
occlusion
these
exposed
DTs
for
immediate
enduring
relief
remains
challenging
due
intricate
structure
oral
environment.
Herein,
pioneering
facile
drop-by-drop
strategy
involving
an
in
situ
generated
natural
supramolecular
hydrogel
formed
by
self-assembling
silk
fibroin
(SF)
tannic
acid
(TA)
within
narrow
DT
space
proposed.
When
SF
TA
aqueous
solutions
are
applied
successively
dentin,
they
penetrate
deeply
coassemble
into
compact
gels,
robustly
adhering
walls.
This
yields
rapid
effect
with
unprecedented
depth
exceeding
250
µm,
maintaining
stable
efficacy
even
under
rigorous
vitro
vivo
erosion
friction
conditions
no
less
than
21
days.
Furthermore,
biocompatibility
effective
properties
verified
through
cell
studies
simulated
settings
rabbit
model.
study,
first
time,
demonstrates
translational
potential
hydrogel-based
desensitizers
treating
DH
prompt
action,
superior
treatment
benefits,
holding
promise
as
clinical-friendly
restorative
delicate-structured
biosystems.
Frontiers in Bioengineering and Biotechnology,
Journal Year:
2024,
Volume and Issue:
12
Published: Feb. 8, 2024
Introduction:
Dental
erosion
and
abrasion
pose
significant
clinical
challenges,
often
leading
to
exposed
dentinal
tubules
dentine
demineralization.
The
aim
of
this
study
was
analyse
the
efficacy
quercetin-encapsulated
hollow
mesoporous
silica
nanocomposites
(Q@HMSNs)
on
prevention
abrasion.
Method:
Q@HMSNs
were
synthesized,
characterized,
evaluated
for
their
biocompatibility.
A
total
130
specimens
(2
mm
×
2
mm)
prepared
randomly
distributed
into
5
treatment
groups
(n
=
26):
DW
(deionized
water,
negative
control),
NaF
(12.3
mg/mL
sodium
fluoride,
positive
Q
(300
μg/mL
quercetin),
HMSN
(5.0
HMSNs),
Q@HMSN
Q@HMSNs).
All
submitted
in
vitro
erosive
(4
cycles/d)
abrasive
challenges
7
days.
DW,
NaF,
immersed
respective
solutions
min,
while
performed
30
s
groups.
Subsequently,
subjected
additional
daily
erosion/abrasion
cycles
another
effects
materials
tubule
occlusion
demineralized
organic
matrix
(DOM)
preservation
examined
by
scanning
electron
microscopy
(SEM).
penetration
depth
rhodamine
B
fluorescein
etched
assessed
using
confocal
laser
(CLSM).
loss
(EDL)
release
type
I
collagen
telopeptide
(ICTP)
measured.
data
analysed
one-way
analysis
variance
(ANOVA)
with
post
hoc
Tukey’s
test
(
α
0.05).
Results:
successfully
synthesized
showed
minimal
toxicity
human
dental
pulp
stem
cells
(HDPSCs)
gingival
fibroblasts
(HGFs).
effectively
occluded
tubules,
resulting
a
thicker
DOM
group.
CLSM
images
more
superficial
than
quercetin,
group
exhibited
significantly
lower
EDL
reduced
ICTP
levels
compared
other
p
<
Conclusion:
hold
promise
inhibiting
promoting
preservation.
Polymers,
Journal Year:
2025,
Volume and Issue:
17(7), P. 886 - 886
Published: March 26, 2025
Three-dimensional
(3D)
printing
is
a
cutting-edge
technology
that
widely
used
in
biomedical
fields
to
construct
various
commercial
products
or
scaffolds
for
theoretical
research.
In
this
review,
3D
technologies
with
different
principles
are
briefly
introduced,
including
selective
laser
melting
(SLM),
sintering
(SLS),
fused
deposition
modeling
(FDM),
stereolithography
(SLA),
and
digital
light
processing
(DLP).
addition,
the
applications
of
dentistry,
such
as
dental
implantology,
prosthodontics,
orthodontics,
maxillofacial
surgery,
tissue
regeneration,
were
summarized.
Furthermore,
perspective
challenges
also
addressed
help
readers
obtain
clear
map
development
dentistry.
Indian Journal of Dental Sciences,
Journal Year:
2025,
Volume and Issue:
17(1), P. 2 - 7
Published: Jan. 1, 2025
Context:
This
study
compared
the
accuracy
of
computer-aided
design
and
manufacturing
(CAD/CAM)
milled
temporary
dental
crowns
using
Metrology
software.
Aims:
The
aim
this
was
to
evaluate
dimensional
CAD/CAM
by
analyzing
gap
distances
across
different
areas
interest
(AOIs).
Settings
Design:
In
vitro
laboratory
a
mandibular
molar
typodont
tooth
model
used.
Methods:
A
digital
crown
created
ExoCAD
Temporary
were
from
polymethyl
methacrylate
technology.
scanned
original
Geomagic
Control
X
metrology
Gap
measured
six
AOIs.
Statistical
Analysis
Used:
Paired
t
-tests
performed
compare
between
master
STL
file
rescanned
files
for
each
AOI.
Results:
Mean
root
mean
square
values
AOIs
ranged
0.040
mm
0.076
mm.
No
statistically
significant
differences
found
(
P
>
0.05
all
comparisons).
Conclusions:
milling
technology
can
produce
with
reliable
prosthesis.
suggests
that
may
offer
clinicians
dependable
option
interim
restorations.
