High cycle fatigue behavior and strengthening mechanisms of laser powder bed fusion pure tantalum DOI

Rongzheng Huang,

Haiqiong Xie,

Lin Guo

et al.

International Journal of Fatigue, Journal Year: 2024, Volume and Issue: unknown, P. 108624 - 108624

Published: Sept. 1, 2024

Language: Английский

Hierarchical microstructure design of multifunctional soft collagen-incorporated 3D hard polyetherketoneketone scaffolds for augmented bone regeneration DOI
Huanhuan Liu, Xiaoyin Liu,

Taiqing Liu

et al.

Composites Part B Engineering, Journal Year: 2024, Volume and Issue: 287, P. 111833 - 111833

Published: Sept. 10, 2024

Language: Английский

Citations

4
Research progress in degradable metal‐based multifunctional scaffolds for bone tissue engineering DOI Creative Commons
Jian He, Kun Li,

Tingkui Wu

et al.

MedComm – Biomaterials and Applications, Journal Year: 2023, Volume and Issue: 2(4)

Published: Oct. 11, 2023

Abstract The increasing prevalence of orthopedic‐related diseases necessitates the development effective orthopedic implants. Conventional metal scaffolds used in devices have limitations such as poor biocompatibility and need for a second surgery to remove scaffold. Degradable metal‐based scaffolds, including multifunctional doped with elements, are rapidly developing tissue engineering strategy aimed at utilizing mechanical biological properties elements create support structure that matches complex bone regeneration environment. Repairing defects involves various tissues, incomplete repair can negatively affect function overall recovery. Therefore, combining degradable materials other active components has great potential enhancing versatility clinical applications scaffolds. Multifunctional better biocompatibility, osteoinductivity, biodegradability, matching mechanical, microenvironmental adjustment capabilities. Moreover, these metal‐doped possess advantages controlled release ions, multifunctionality, faster degradation. This review focuses on techniques constructing Furthermore, this study discussed designing biodegradable by integrating multiple strategies.

Language: Английский

Citations

10
Engineering gyroid scaffolds: an approach for bone implantation using SLM printing DOI
Vasuudhaa Sonawane, Ratnakar Ghorpade, Basavraj S. Kothavale

et al.

International journal of metallic materials., Journal Year: 2025, Volume and Issue: unknown, P. 1 - 9

Published: Jan. 13, 2025

Language: Английский

Citations

0
Incorporation of tantalum into PEEK and grafting of berbamine facilitate osteoblastogenesis for enhancing osseointegration and inhibit osteoclastogenesis for preventing aseptic loosening DOI Creative Commons
Chong‐Jing Zhang,

En Xie,

Zeyuan Zhong

et al.

Composites Part B Engineering, Journal Year: 2025, Volume and Issue: unknown, P. 112242 - 112242

Published: Feb. 1, 2025

Language: Английский

Citations

0
Innovative 3D-Printed Porous Tantalum Cage with Non-Window Design to Accelerate Spinal Fusion: A proof-of-concept study DOI Creative Commons
Hang Liang,

Jingyao Tu,

Bingjin Wang

et al.

Materials Today Bio, Journal Year: 2025, Volume and Issue: 31, P. 101576 - 101576

Published: Feb. 15, 2025

Language: Английский

Citations

0
Progress of porous tantalum surface-modified biomaterial coatings in bone tissue engineering DOI Creative Commons
Aiguo Liu, Chenxu Wang,

Ziwen Zhao

et al.

Journal of Materials Science Materials in Medicine, Journal Year: 2025, Volume and Issue: 36(1)

Published: March 5, 2025

Tantalum (Ta) metal has emerged as a prominent material within the realm of bone tissue engineering, owing to its favorable biocompatibility, commendable mechanical attributes, and notable biological properties such osteoconductivity, osteoinductivity, angiogenic potential. However, clinical applications have expanded, Ta implants unveiled spectrum limitations. Consequently, porous tantalum (PTa) garnered escalating interest, attributable unique microstructural tunable characteristics, inherent biocompatibility. Various methodologies been proposed modify surface PTa, with aim accelerating enhancing osseous integration while fostering more robust osseointegration. Strategic modifications potential augment advantages thereby offering diverse avenues for exploration effects on PTa. This review elucidates ongoing research endeavors concerning biomaterial coatings applied PTa surfaces in context engineering.

Language: Английский

Citations

0
Hydrogel composite scaffold repairs knee cartilage defects: a systematic review DOI Creative Commons

Dongxu Tang,

Hao Song, Cheng Yan

et al.

RSC Advances, Journal Year: 2025, Volume and Issue: 15(13), P. 10337 - 10364

Published: Jan. 1, 2025

Currently, the incidence of cartilage defects in knee joints owing to different causes is increasing every year, and surgery most common treatment strategy.

Language: Английский

Citations

0
New Direction in Antimicrobial Delivery System: Preparation and Applications of Hydrogel Microspheres DOI Creative Commons
Jiapeng Li,

Guo-yang Wei,

Ye Yuan

et al.

Pharmaceutics, Journal Year: 2025, Volume and Issue: 17(4), P. 529 - 529

Published: April 17, 2025

Antimicrobial delivery systems have undergone extensive development, yet conventional carriers still exhibit limitations such as low loading capacity, inadequate controlled release mechanisms, and cytotoxicity. Recent studies increasingly demonstrated the potential of Hydrogel Microspheres (HMSs) for antimicrobial delivery. These microspheres small dimensions, high drug-loading ability to achieve deep-targeted delivery, complemented by adjustable physicochemical properties biocompatibility that create favorable conditions transportation. This review systematically examines HMS preparation strategies, characteristic properties, transported antimicrobials, therapeutic applications. Particular emphasis is placed on critical parameters governing performance, especially those influencing drug dynamics. We conclude addressing current challenges proposing actionable strategies material optimization clinical translation. work aims advance HMS-based more effective infection control.

Language: Английский

Citations

0
Polymer Scaffolds for peripheral nerve injury repair DOI

Shuhang Yang,

Li Chen, Changning Bai

et al.

Progress in Materials Science, Journal Year: 2025, Volume and Issue: unknown, P. 101497 - 101497

Published: April 1, 2025

Language: Английский

Citations

0
Advances in 3D-printed scaffold technologies for bone defect repair: materials, biomechanics, and clinical prospects DOI Creative Commons
Jie Sun, Chen Cao, Bo Zhang

et al.

BioMedical Engineering OnLine, Journal Year: 2025, Volume and Issue: 24(1)

Published: April 30, 2025

The treatment of large bone defects remains a significant clinical challenge due to the limitations current grafting techniques, including donor site morbidity, restricted availability, and suboptimal integration. Recent advances in 3D bioprinting technology have enabled fabrication structurally functionally optimized scaffolds that closely mimic native tissue architecture. This review comprehensively examines latest developments 3D-printed for regeneration, focusing on three critical aspects: (1) material selection composite design encompassing metallic; (2) structural optimization with hierarchical porosity (macro/micro/nano-scale) biomechanical properties tailored; (3) biological functionalization through growth factor delivery, cell seeding strategies surface modifications. We critically analyze scaffold performance metrics from different research applications, while discussing translational barriers, vascular network establishment, mechanical stability under load-bearing conditions, manufacturing scalability. concludes forward-looking perspective innovative approaches such as 4D dynamic scaffolds, smart biomaterials stimuli-responsive properties, integration artificial intelligence patient-specific optimization. These technological advancements collectively offer unprecedented opportunities address unmet needs complex reconstruction.

Language: Английский

Citations

0