Nanophotonics,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 17, 2025
Abstract
Plasmonic
biosensors
are
powerful
platforms
for
detecting
various
types
of
analytes.
Specifically,
surface-enhanced
Raman
spectroscopy
(SERS)
can
enable
label-free
and
selective
detection.
Shiga
toxin-producing
Escherichia
coli
(STEC)
represents
zoonotic
pathogens
that
cause
severe
diseases,
such
as
hemolytic
uremic
syndrome
(HUS),
the
most
important
acute
renal
failure
in
children.
To
date,
there
no
effective
therapies
STEC
infection,
available
diagnostic
methods
complex
inconclusive.
Here,
a
novel
nanopattern
fabricated
by
electron
beam
lithography
with
remarkable
plasmonic
properties
is
employed
SERS
substrate
realizing
specific
recognition
Stx1a,
Stx2a,
third
variation
latter.
A
limit
detection
(LOD)
6.8
pM
Stx1a
2
Stx2a
was
achieved.
Our
approach
supported
using
principal
component
analysis
(PCA)
appears
to
be
valid
alternative
conventional
methods,
allowing
real-time
fast
situ
analysis.
Small,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 7, 2025
Abstract
Owing
to
its
high
sensitivity,
surface‐enhanced
Raman
scattering
(SERS)
has
immense
potential
for
the
identification
of
lung
cancer
from
variation
in
volatile
biomarkers
exhaled
gas.
However,
two
prevailing
factors
limit
application
SERS:
1)
adsorption
target
molecules
into
SERS
hotspots
and
2)
detection
specificity
multiple
interference
environments.
To
improve
density
hotspots,
3D
Au@Ag‐Au
particles
are
prepared
a
porous
nanoframes
(PPFs)
based
plasmonic
structure,
which
facilitated
richer
local
electromagnetic
field
distribution
among
Au
nanocubic
(NC)
cores,
Au‐Ag
nanoframes,
nanoparticles,
thereby
promoting
probability
gaseous
aldehydes
hotspots.
L‐cysteines
(l‐Cys)‐modified
PPFs
proposed
as
benzaldehyde
(BA)
gas
carrier
accurately
detect
complex
gases
eliminate
other
components.
Unlike
conventional
use
4‐aminothiophenol
linker
molecule,
novel
L‐Cys‐modified
substrate
is
sensitive
toward
aldehyde
immune
organic
compounds
(ethanol,
cyclohexane,
toluene,
etc.).
Furthermore,
medical
mask
consisting
this
designed
realize
intelligent
BA
concentrations
assisted
by
machine
learning
algorithm.
Journal of Agricultural and Food Chemistry,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 13, 2025
Nitrite
is
an
important
chemical
intermediate
in
the
nitrogen
cycle
and
ubiquitously
present
environmental
biological
systems
as
a
metabolite
or
additive
agricultural
food
industries.
However,
nitrite
can
also
be
toxic
excessive
concentrations.
As
such,
development
of
quick,
sensitive,
portable
assays
for
its
measurement
desirable.
In
this
review,
we
summarize
working
principles
applications
surface-enhanced
Raman
spectroscopy
(SERS)
rapid,
portable,
ultrasensitive
method
detection
showcase
applicability
various
water,
food,
samples.
The
challenges
opportunities
future
developments
are
discussed.
International Journal of Molecular Sciences,
Journal Year:
2025,
Volume and Issue:
26(2), P. 709 - 709
Published: Jan. 15, 2025
Nanozymes,
a
kind
of
nanoparticles
with
enzyme-mimicking
activities,
have
attracted
considerable
attention
due
to
their
robust
catalytic
properties,
ease
preparation,
and
resistance
harsh
conditions.
By
combining
nanozymes
surface-enhanced
Raman
spectroscopy
(SERS)
technology,
highly
sensitive
selective
sensors
been
developed.
These
are
capable
detecting
wide
range
analytes,
such
as
foodborne
toxins,
environmental
pollutants,
biomedical
markers.
This
review
provides
an
overview
recent
advancements
in
the
synthesis
surface
modification
nanozymes,
highlighting
ability
mimic
multiple
enzymes
enhance
performance.
In
addition,
we
explore
development
applications
nanozyme-based
SERS
food
contaminants,
The
concludes
perspectives
challenges
facing
field,
involving
need
for
deeper
understanding
nanozyme
principles
mechanisms,
standardized
systems
characterization,
engineering
tailored
properties
specific
applications.
Finally,
discuss
potential
integrating
various
techniques
create
multi-modal
detection
platforms,
paving
way
next
generation
analytical
tools
fields
safety,
monitoring,
diagnostics.
