Phosphorescence-Based Visualization of the Dynamic Coordination-Driven Assembly in Gelation DOI
Ying Wang, Jiazhuo Li,

Ronghui Zhou

et al.

Chemistry of Materials, Journal Year: 2024, Volume and Issue: 36(21), P. 10786 - 10794

Published: Nov. 1, 2024

Coordination-driven supramolecular hydrogels feature excellent processability and dynamic responsibility thus are appealing for applications such as biomedical photonics. Since they constructed via hierarchical assembly, the gelation processes difficult to control in a highly efficient manner, leading limited transparency. For formation of hydrogel, stepwise introduction water is essential gelation. Phosphorescence with high H2O sensitivity can be explored situ monitoring precise understanding process. Herein, hydrogel from Gd3+-adenosine monophosphate (AMP) assembly was chosen model, which formed strong Gd3+-PO3 coordination π–π stacking A bases. On basis guest inclusion phosphorescence inducing Gd3+-AMP matrix, thioflavin-T (ThT, cyan fluorescence) Pt(II) meso-tetra(4-carboxyphenyl) porphine (PtTCPP, red phosphorescence) were coencapsulated probe. Via luminescence changes, process visualized, two kinds cloudy side products (NPs sol, indistinguishable naked eye) identified. Further calorimetric investigation on above allowed improvement transparency by changing synthesis temperature. The obtained flexible transparent room-temperature (RTP) implantable optical waveguide-based oxygen sensing.

Language: Английский

Hydrogel Fibers‐Based Biointerfacing DOI

Xingmei Chen,

Yinghui Feng, Pei Zhang

et al.

Advanced Materials, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 22, 2024

Abstract The unique 1D structure of fibers offers intriguing attributes, including a high length‐to‐diameter ratio, miniatured size, light‐weight, and flexibility, making them suitable for various biomedical applications, such as health monitoring, disease treatment, minimally invasive surgeries. However, traditional fiber devices, typically composed rigid, dry, non‐living materials, are intrinsically different from the soft, wet, living essence biological tissues, thereby posing grand challenges long‐term, reliable, seamless interfacing with systems. Hydrogel have recently emerged promising candidate, in light their similarity to tissues mechanical, chemical aspects, well distinct geometry. In this review, comprehensive overview recent progress hydrogel fibers‐based biointerfacing technology is provided. It thoroughly summarizes manufacturing strategy functional design, especially optical electron conductive performance, responsiveness triggers thermal, magnetic field ultrasonic wave, etc. Such attributes enable which also examined detail. Future potential directions, biosafety, long‐term reliability, sterilization, multi‐modalities integration intelligent therapeutic systems, raised. This review will serve valuable resource further advancement implementation next‐generation technology.

Language: Английский

Citations

4
Study on Highly Sensitive Capacitive Pressure Sensor Based on Silk Fibroin-Lignin Nanoparticles Hydrogel DOI
Lei Wang, Yue Wang, Simin Peng

et al.

Biomacromolecules, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 9, 2025

Silk fibroin (SF) hydrogel has been proven to have excellent applications in the field of pressure sensors, but its sensing performance still needs improvement. A flexible prepared from natural macromolecular materials was developed, and lignin nanoparticles (LNPs) were introduced during preparation SF hydrogel. When LNPs account for 3% SF, unit SF-LNPs3% exhibits high stress sensitivity (1.32 kPa–1), fast response speed (<0.1 s), superior cycle stability (≥8000 cycles). The sensor can detect human motion information, such as finger bending, elbow pulse signals. worn at vocal cord position, it peak value characteristic signal wearer speaks. This work demonstrates that shows great potential sensors.

Language: Английский

Citations

0
Optical characterization of chitosan/poly(vinyl alcohol) hybrid hydrogels and the effect of genipin crosslinking and multiwalled carbon nanotube fillers DOI Creative Commons
Itzel Marisol Garnica-Palafox, Amado M. Velázquez-Benítez, Francisco M. Sánchez-Arévalo

et al.

Optical Materials, Journal Year: 2025, Volume and Issue: unknown, P. 116686 - 116686

Published: Jan. 1, 2025

Language: Английский

Citations

0
“Bioactive” Therapeutic Contact Lens Triggered by Biomimetic Chiral Helical Nanoarchitectonics for Rapid Corneal Repair DOI
Xiaoying Luo, Songjiao Zhao, Tao Wang

et al.

ACS Nano, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 25, 2025

Consistent corneal epithelial injury would cause chronic inflammation, neovascularization, and even scarring, resulting in vision loss. Rapid repair is crucial for treatment, within which the use of therapeutic contact lenses presents great promise. A challenge how to achieve rapid severely deficient epithelium regulation oxidative stress environment simultaneously. Herein, a "bioactive" lens, mimicking layered helical structure native cornea, designed based on assembly cellulose nanocrystals (CNCs) inside poly(hydroxyethyl methacrylate) (PHEMA) with CeOx formed CNCs' surface (CeOx/CNC@CNC-PHEMA). The obtained CeOx/CNC@CNC-PHEMA hydrogel possesses chiral that regulates microenvironment, nanoscaled (CeOx/CNC) acts as reactive oxygen species (ROS) scavenger triggers lens repair. This meets conditions including high degree transparency, excellent mechanical properties, ROS-scavenging efficacy, significant enhancement biocompatibility. Importantly, adhesion proliferation human cells hydrogels are successful. An vitro damage model vivo animal experiments were conducted, results revealed realized migration antioxidant, anti-inflammatory, antineovascular effects, achieving modulation ocular evidencing property lens. biotopological biomimetic architecture has provided rational strategy

Language: Английский

Citations

0
Harnessing Liposomal Nanocellulose Hydrogel for NIR-Light Driven On-Demand Drug Delivery DOI Creative Commons
Puja Gangurde, Zahra Gounani, Jacopo Zini

et al.

Carbohydrate Polymer Technologies and Applications, Journal Year: 2025, Volume and Issue: unknown, P. 100787 - 100787

Published: April 1, 2025

Language: Английский

Citations

0
Advanced hydrogel material for colorectal cancer treatment DOI Creative Commons
Yu Guo,

Min Wang,

Yu‐Zhong Zhang

et al.

Drug Delivery, Journal Year: 2024, Volume and Issue: 32(1)

Published: Dec. 31, 2024

Colorectal cancer is one of the most common cancers worldwide, and its incidence rates are increasing every year. Treatments for CRC include surgical resection, chemotherapy, radiotherapy, targeted therapy, immunotherapy. Although various agents have been used in treatment malignant tumors, they not as effective expected. This primarily owing to lack selectivity, poor solubility, severe side effects agents. It necessary develop more efficient drug delivery systems precise targeting tumor site therapeutic meet clinical needs. A hydrogel a three-dimensional network material composed crosslinked chains hydrophilic or hydrophobic groups polymer backbone. Hydrogels possess useful properties including high water content, adjustable physical characteristics, elasticity, flexibility, reversible swelling, multifunctionality. These render them ideal biomaterials with broad range applications biomedicine bioengineering. In this review, we introduce pathophysiology current advances summarize hydrogels different materials well smart response carriers treatment. We also analyze unique advantages challenges using therapy.

Language: Английский

Citations

2
Phosphorescence-Based Visualization of the Dynamic Coordination-Driven Assembly in Gelation DOI
Ying Wang, Jiazhuo Li,

Ronghui Zhou

et al.

Chemistry of Materials, Journal Year: 2024, Volume and Issue: 36(21), P. 10786 - 10794

Published: Nov. 1, 2024

Coordination-driven supramolecular hydrogels feature excellent processability and dynamic responsibility thus are appealing for applications such as biomedical photonics. Since they constructed via hierarchical assembly, the gelation processes difficult to control in a highly efficient manner, leading limited transparency. For formation of hydrogel, stepwise introduction water is essential gelation. Phosphorescence with high H2O sensitivity can be explored situ monitoring precise understanding process. Herein, hydrogel from Gd3+-adenosine monophosphate (AMP) assembly was chosen model, which formed strong Gd3+-PO3 coordination π–π stacking A bases. On basis guest inclusion phosphorescence inducing Gd3+-AMP matrix, thioflavin-T (ThT, cyan fluorescence) Pt(II) meso-tetra(4-carboxyphenyl) porphine (PtTCPP, red phosphorescence) were coencapsulated probe. Via luminescence changes, process visualized, two kinds cloudy side products (NPs sol, indistinguishable naked eye) identified. Further calorimetric investigation on above allowed improvement transparency by changing synthesis temperature. The obtained flexible transparent room-temperature (RTP) implantable optical waveguide-based oxygen sensing.

Language: Английский

Citations

1